Relationship Between Borderline Personality Disorder and Axis I Diagnosis in Severity of Depression and Anxiety

1999 ◽  
Vol 60 (11) ◽  
pp. 752-758 ◽  
Author(s):  
Katherine Anne Comtois ◽  
Deborah S. Cowley ◽  
David L. Dunner ◽  
Peter P. Roy-Byrne
2006 ◽  
Vol 67 (10) ◽  
pp. 1583-1590 ◽  
Author(s):  
Vedat Sar ◽  
Gamze Akyuz ◽  
Nesim Kugu ◽  
Erdinc Ozturk ◽  
Hayriye Ertem-Vehid

2009 ◽  
Vol 23 (4) ◽  
pp. 357-369 ◽  
Author(s):  
Mary C. Zanarini ◽  
Leah K. Barison ◽  
Frances R. Frankenburg ◽  
D. Bradford Reich ◽  
James I. Hudson

2008 ◽  
Vol 7 (S1) ◽  
Author(s):  
Ioannis Pantoularis ◽  
George Garyfallos ◽  
Martha Lobtzianidou ◽  
Aristidis Livanos ◽  
Ioannis Dasoukis ◽  
...  

2016 ◽  
Vol 31 ◽  
pp. 29-36 ◽  
Author(s):  
G.K. O’Malley ◽  
L. McHugh ◽  
N. Mac Giollabhui ◽  
J. Bramham

AbstractObjectiveTo characterize adults with comorbid attention-deficit/hyperactivity-disorder (ADHD) and borderline personality disorder (BPD) with regard to ADHD symptoms, psychopathology, cognitive functioning and psychosocial factors.MethodA between-group design compared a group of individuals diagnosed with ADHD (n = 40) with a group diagnosed with BPD and who also met the criteria for ADHD (ADHD + BPD) (n = 20).ResultsSignificant differences were observed for both childhood and current impulsivity symptoms, whereby ADHD + BPD exhibited increased impulsivity; no differences on self-report and cognitive measures of impulsivity were reported. The ADHD + BPD group scored significantly higher on measures of depression, anxiety and numerous other axis I and II conditions. The ADHD + BPD group scored significantly lower on most measures of intellectual functioning and attention, however largely not on those relating to response inhibition. Furthermore, group differences were observed for psychosocial factors, including education, substance use and criminal record.ConclusionComorbid ADHD and BPD is characterized by more symptoms of impulsivity, additional psychopathology, comparatively lower intellectual and attentional functioning and increased psychosocial difficulties.


2011 ◽  
Vol 26 (S2) ◽  
pp. 816-816
Author(s):  
H. Silva Ibarra ◽  
J. Villarroel Garrido ◽  
P. Iturra Constant ◽  
S. Jerez Concha ◽  
M.L. Bustamante Calderon ◽  
...  

Neuroticism is characterized by emotional instability and the tendency to experience negative emotions such as anger, anxiety and depressed mood. Subjects with borderline personality disorder (BPD) present this personality dimension as a temperamental core trait. There has been proposed that neuroticism can appropriately describe the most important characteristics of BPD. The polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) has been implicated in depression, anxiety and suicide. It is estimated that 5-HTTLPR polymorphism account to 7 to 9% of inherited variance of neuroticism in personality. The aim of this study is to evaluate the association between neuroticism and 5-HTTLPR polymorphism in BPD. We evaluate personality with NEO PI R inventory in 104 BPD subjects (76 female/28 male) that did not meet criteria for axis I diagnoses and other personality disorders. The genetic analysis of 5-HTTLPR were performed determining the presence of long and short alleles, subjects were grouped in long/long (LL) and S-carriers (LS+SS). Statistical analysis were tested with parametric and correlation method with Stata10. We found significant difference in neuroticism between the genotype groups (F = 8.57, p = 0.0004) and lower levels of neuroticism in LL than S-carriers. Female have higher neuroticism than male. 5-HTTLPR polymorphism explains 18.02% of inherited variance in neuroticism. The S-carriers had 11.9 times higher risk of presenting elevated neuroticism compared with LL. We conclude that there are relation between 5-HTTLPR polymorphism and neuroticism in BPD. These results should contribute to the genetic study of BPD.


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