scholarly journals Use of a design challenge to develop postural support devices for intermediate wheelchair users

2017 ◽  
Vol 6 ◽  
Author(s):  
Brenda N. Onguti ◽  
Deepti Tanuku ◽  
Elizabeth J. Himelfarb Hurwitz ◽  
Nathaniel C. Moller ◽  
Youseph Yazdi ◽  
...  

The provision of an appropriate wheelchair, one that provides proper fit and postural support, promotes wheelchair users’ physical health and quality of life. Many wheelchair users have postural difficulties, requiring supplemental postural support devices for added trunk support. However, in many low- and middle-income settings, postural support devices are inaccessible, inappropriate or unaffordable. This article describes the use of the design challenge model, informed by a design thinking approach, to catalyse the development of an affordable, simple and robust postural support device for low- and middle-income countries. The article also illustrates how not-for-profit organisations can utilise design thinking and, in particular, the design challenge model to successfully support the development of innovative solutions to product or process challenges.

Author(s):  
Leila H Abdullahi ◽  
Gregory D Hussey ◽  
Hassan Mahomed ◽  
Charles Shey Wiysonge

2018 ◽  
Vol 18 (5) ◽  
pp. 369-381 ◽  
Author(s):  
Carolina L. Bellera ◽  
Maria L. Sbaraglini ◽  
Alan Talevi

Neglected diseases comprise a number of infectious diseases historically endemic to low- and middle-income countries, though recently they have spread to high-income countries due to human migrations. In the past, pharmaceutical companies have shown hesitant to invest in these health conditions, due to the limited return on investment. As a result, the role of the academic sector and not-for-profit organizations in the discovery of new drugs for neglected diseases has been particularly relevant. Here, we review recent applications of modern drug discovery technologies in the field of neglected diseases, including high-throughput screening, in silico screening and computer-aided drug design. The suitability and perspectives of each approach are discussed depending on the context, along with the technology and translational gaps influencing them.


2012 ◽  
Author(s):  
Joop de Jong ◽  
Mark Jordans ◽  
Ivan Komproe ◽  
Robert Macy ◽  
Aline & Herman Ndayisaba ◽  
...  

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