scholarly journals Immunohistochemical analysis of angiogenesis by CD34 and mast cells by toluidine blue in different grades of oral squamous cell carcinoma

2016 ◽  
Vol 20 (3) ◽  
pp. 467 ◽  
Author(s):  
PramodSangamesh Ingaleshwar ◽  
Siddharth Pandit ◽  
Dinkar Desai ◽  
CPramod Redder ◽  
AkhilS Shetty ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Mast Cells ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Toluidine Blue ◽  
Immunohistochemical Analysis

scholarly journals A comparative analysis of toluidine blue with frozen section in oral squamous cell carcinoma

2012 ◽  
Vol 10 (1) ◽  
Author(s):  
Montasir Junaid ◽  
Moaz M Choudhary ◽  
Zain A Sobani ◽  
Ghulam Murtaza ◽  
Sadaf Qadeer ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Comparative Analysis ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Toluidine Blue ◽  
Frozen Section

scholarly journals The Role of Mast Cells on Angiogenesis in Oral Squamous Cell Carcinoma

2012 ◽  
pp. e190-e196 ◽  
Author(s):  
M. Kalra ◽  
N. Rao ◽  
K. Nanda ◽  
F. Rehman ◽  
KL. Girish ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Mast Cells ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell

scholarly journals Stathmin! An immunohistochemical analysis of the novel marker in Oral Squamous Cell Carcinoma and Oral Leukoplakia.

2020 ◽  
Vol 21 (11) ◽  
pp. 3317-3323
Author(s):  
Purnima Vadla ◽  
Sivaranjani Yeluri ◽  
G Deepthi ◽  
Venkateswara Rao Guttikonda ◽  
Sravya Taneeru ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Immunohistochemical Analysis ◽  
Oral Leukoplakia ◽  
The Novel

scholarly journals Immunohistochemical Analysis of the Beclin-1 Expression Predicts the Progression of Oral Squamous Cell Carcinoma

2021 ◽  
Vol 18 (21) ◽  
pp. 11125
Author(s):  
Ida Barca ◽  
Chiara Mignogna ◽  
Daniela Novembre ◽  
Francesco Ferragina ◽  
Maria Giulia Cristofaro
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Index ◽  
Immunohistochemical Analysis ◽  
Tumour Cells ◽  
Beclin 1 ◽  
Immunohistochemical Techniques

Background: Autophagy is a cellular process responsible for maintaining homeostasis; a dysregulation of this process is involved in the development and progression of neoplasms. Beclin-1 is one of the major proteins linked to autophagy. However, the data regarding the association between the role of Beclin-1 and the progression of Oral Squamous Cell Carcinoma (OSCC) are rather low. For this reason, the objective of this study is to evaluate, through immunohistochemical techniques, the prognostic role of the expression of Beclin-1 autophagy marker in patients with OSCC. Methods: This is a single-centre retrospective study that includes patients with OSCC admitted to the Maxillofacial Unit of “Magna Graecia” University between January 2019 and September 2020. All the samples obtained from surgery were treated with anti Beclin-1 antibodies and subjected to immunohistochemical methods. Results: A total of 26 samples were analysed and the following variables were evaluated for each: percentage of positive Beclin-1 expression by tumour cells, signal strength of tumour cells, and total score. The variables considered were first normalised according to the D’Agostino and Pearson test, then analysed using the Pearson linear correlation coefficient: a statistically significant correlation was found between the parameters infiltration-intensity (p = 0.0088), infiltration-percent (p = 0.0123), intensity-total score (p = 0.0060). Conclusions: The immunohistochemical evaluation of Beclin-1 revealed a statistically significant correlation between the intensity of the molecule’s expression and a greater degree of infiltration of the neoplasm. Beclin-1 can, therefore, be considered a valid prognostic index of disease.

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