scholarly journals Subaortic membrane with rupture of sinus of Valsalva presented with infective endocarditis and its thromboembolic complications

2012 ◽  
Vol 3 (1) ◽  
pp. 43-45
Author(s):  
Nirdesh Jain ◽  
Manish Gutch ◽  
Rahul Arora ◽  
Roopali Khanna
Keyword(s):  
Infective Endocarditis ◽  
Thromboembolic Complications ◽  
Sinus Of Valsalva ◽  
Subaortic Membrane

Early and Long-Term Results of a Valve-Sparing Operation for Marfan Syndrome

Circulation ◽  
1999 ◽  
Vol 100 (suppl_2) ◽  
Author(s):  
Emma J. Birks ◽  
Carole Webb ◽  
Anne Child ◽  
Rosemary Radley-Smith ◽  
Magdi H. Yacoub
Keyword(s):  
Infective Endocarditis ◽  
Marfan Syndrome ◽  
Ascending Aorta ◽  
Long Term Results ◽  
Thromboembolic Complications ◽  
Actuarial Survival ◽  
Acute Dissection ◽  
Valve Sparing

Background —We have previously described the experience, rationale, and development of a valve preserving technique, but its role in patients with Marfan syndrome has not previously been defined. Here, we attempt to determine the early and long-term results, timing, and determinants of outcome of this operation in patients with Marfan syndrome. Methods and Results —Since 1979, 82 patients (73.2% of all patients with Marfan syndrome undergoing resection of aneurysm of the ascending aorta) were operated on using this technique. Ages ranged from 2 to 69 years (mean, 33.9 years). In all, there were 4 early deaths (4.9%), 2 with acute dissection and 2 with chronic aneurysm operated on as emergencies. There were no early deaths in 67 patients operated on electively. Actuarial survival for patients operated for chronic aneurysm was 94.2%, 94.2%, and 94.2% at 1, 5, and 10 years, respectively; that for acute dissection was 72.7%, 63.6%, and 63.6%; and that for chronic dissection was 100%, 85.7%, and 75.0%. The probability of needing reoperation was 5.7%, 17.3%, and 17.3% at 1, 5, and 10 years. There were no instances of infective endocarditis or thromboembolic complications except in 2 patients operated on early in the series who had cusp extension. At the end of the follow-up, trivial or no aortic regurgitation was demonstrated in 33.3%, mild in 45.6%, moderate in 21.1%, and severe in 0. Conclusions —Valve-sparing operations are feasible in most patients with Marfan syndrome; they are applicable to patients with both dissection and chronic aneurysm. The early and long-term results are encouraging. Results are better in the absence of dissection, and prophylactic operation is warranted in some cases.

Infective Endocarditis at the Turn of the Century: Literature Review

10.12737/5947 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Кузьмина ◽  
Natalya Kuzmina ◽  
Добрынина ◽  
Irina Dobrynina ◽  
Нелидова ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Heart Valves ◽  
Clinical Medicine ◽  
Turn Of The Century ◽  
Infectious Endocarditis ◽  
Thromboembolic Complications ◽  
Scientific Review ◽  
Current Characteristics ◽  
The Right ◽  
Tremendous Impact

In recent decades there have been significant changes in the clinic of infectious endocarditis. In the presented scientific review detailed analysis of the current characteristics of the clinic and diagnosis is carried out. There is a growing incidence worldwide. Persons of elderly and senile age began to hurt more. According to the latest data, both in Western countries and in Russia to first place in the etiologic structure of infective endocarditis is Staphylococcus aureus. Modern disease is characterized by further increase in the frequency of primary infective endocarditis caused by unmodified heart valves. The septic forms of the disease began to meet less frequently, im-mune pathological manifestations of the disease are observed more often. The classic clinical picture is revealed not always, atypical forms of the disease, the cases of myocardium failure in the patients with infectious endocarditis are detected often. Thromboembolic complications still are among the most frequent and severe complications of infective endocarditis and its have a tremendous impact on his forecast. Recently come to the forefront of cerebral thromboembolic complications. Relapsing course of the disease is more common. The frequency of infective endo-carditis with damage to the valves of the right heart increases. Thus, timely diagnosis of infective endocarditis re-mains a topical problem of modern clinical medicine. The authors conclude that it is necessary to carry out further research in this direction.

Silent rupture of sinus of Valsalva aneurysm: a refutation of the Okham's razor principle

2011 ◽  
Vol 21 (6) ◽  
pp. 713-715 ◽  
Author(s):  
Joseph Dayan ◽  
Suvro Sett ◽  
Usha Krishnan
Keyword(s):  
Infective Endocarditis ◽  
Cardiac Failure ◽  
Adverse Outcomes ◽  
Unusual Presentation ◽  
Sinus Of Valsalva ◽  
Sinus Of Valsalva Aneurysm ◽  
Unruptured Aneurysms ◽  
Congenital Lesion ◽  
History Of ◽  
Physical Examinations

AbstractAneurysm of the sinus of Valsalva is an uncommon congenital lesion rarely reported in children. Unruptured aneurysms commonly go undiagnosed until a rupture has occurred. Usually, ruptured sinus of Valsalva presents with cardiac failure. There may be a history of trauma or infective endocarditis preceding the rupture. Asymptomatic paediatric presentation of ruptured sinus of Valsalva is rare. We discuss the cases of two children who presented with a murmur and were diagnosed with ruptured sinus of Valsalva. This unusual presentation in children highlights the importance of careful routine physical examinations and the evaluation of new murmurs. The Okham's razor principle states that “when you hear hoofbeats – think horses not zebras”. Sometimes, it is important to think beyond the usual in medicine, to avoid missing lesions that, if left untreated, could lead to adverse outcomes.

scholarly journals Predictive value of thromboembolic complications in infective endocarditis, the possibility of prevention.

2018 ◽  
Vol 96 (2) ◽  
pp. 129-136
Author(s):  
M. V. Taranova ◽  
T. V. Androsova ◽  
L. V. Kozlovskaya ◽  
L. A. Strizhakov ◽  
M. V. Lebedeva ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Ischemic Stroke ◽  
Surgical Treatment ◽  
Infective Endocarditis ◽  
Heart Attack ◽  
Thromboembolic Complication ◽  
Thromboembolic Complications ◽  
Intracranial Hemorrhages ◽  
Treatment And Prevention ◽  
The Brain

Thromboembolic syndrome is a formidable complication of infectious endocarditis (IE), which significantly worsens the prognosis. Data of literature and own results of studying of this problem are given. Among 64 patients of IE, who were under the supervision of the authors, thromboembolic syndrome was observed in 23 (36%; according to the literature - in 33-50%), including recurrent in 6. The main causative agent of the disease in this group was Staphylococcus aureus (42%), which is consistent with the data of the majority of authors, in the presence of large mobile vegetation with localization on the mitral valve, among patients without embolic events - Streptococcus viridans (47%) in the presence of smaller vegetation mainly on the aortic valve. The most dangerous thromboembolic complication was ischemic stroke in 8 (12.5%) patients, but embolic heart attack of the brain and myocardium is not always diagnosed in patients due to atypical course. The basis for the treatment and prevention of complications of IE, including thromboembolism, is early initiated adequate antibiotic therapy; at the same time, the principles of antithrombotic therapy in IE developed less. Given the high risk of intracranial hemorrhages, the decision to conduct thrombolytic therapy should be made individually by the so-called endocarditis team. The article discusses the indications for urgent surgical treatment to prevent thromboembolism.

scholarly journals Sinus of Valsalva Pseudoaneurysm as a Sequela to Infective Endocarditis

2016 ◽  
Vol 43 (1) ◽  
pp. 46-48 ◽  
Author(s):  
Chin C. Lee ◽  
Robert J. Siegel
Keyword(s):  
Infective Endocarditis ◽  
Antibiotic Therapy ◽  
Recurrent Infection ◽  
Sinus Of Valsalva ◽  
Intravenous Antibiotic ◽  
Severe Aortic Regurgitation ◽  
Coronary Cusp ◽  
Vestibular Toxicity ◽  
Group B

Pseudoaneurysm is an uncommon sequela of infective endocarditis. We treated a 44-year-old man who had an active case of group B streptococcal infective endocarditis of the aortic valve despite no evidence of valvular dysfunction or vegetation on his initial transesophageal echocardiogram. After completing 6 weeks of intravenous antibiotic therapy, the patient developed a sinus of Valsalva pseudoaneurysm and severe aortic regurgitation caused by partial detachment of the left coronary cusp. We used a pericardial patch to close the pseudoaneurysm and repair the coronary cusp. This case shows the importance of routine clinical follow-up evaluation in infective endocarditis, even after completion of antibiotic therapy. Late sequelae associated with infective endocarditis or its therapy include recurrent infection, heart failure caused by valvular dysfunction (albeit delayed), and antibiotic toxicity such as aminoglycoside-induced nephropathy and vestibular toxicity.

scholarly journals Infective endocarditis of an aorto-right atrial fistula caused by asymptomatic rupture of a sinus of Valsalva aneurysm: a case report

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Akihiko Ikeda ◽  
Tomomi Nakajima ◽  
Taisuke Konishi ◽  
Kanji Matsuzaki ◽  
Akinori Sugano ◽  
...  
Keyword(s):  
Case Report ◽  
Infective Endocarditis ◽  
Right Atrial ◽  
Sinus Of Valsalva ◽  
Sinus Of Valsalva Aneurysm

scholarly journals Trifoliate sinus of Valsalva pseudoaneurysms with aortocavitary fistula: a critical complication of infective endocarditis

2019 ◽  
Vol 12 (6) ◽  
pp. e230759
Author(s):  
Manish Shaw ◽  
Niraj Nirmal Pandey ◽  
Arun Sharma ◽  
Sanjeev Kumar
Keyword(s):  
Infective Endocarditis ◽  
Sinus Of Valsalva

Echocardiography to Diagnose an Evolving Sinus of Valsalva Fistula From Infective Endocarditis

2021 ◽  
Author(s):  
Jon Lucaj ◽  
Peter Paik ◽  
Nazia Siddiqui ◽  
Ashley Miller ◽  
Kinjal Patel ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Sinus Of Valsalva

scholarly journals Sinus of Valsalva Aneurysm and Infective Endocarditis Involving a Bicuspid Aortic Valve in an Infant With Trisomy 21

2018 ◽  
Vol 8 (3) ◽  
pp. 763-768
Author(s):  
Nicole A. Croom ◽  
Nicole Therrien ◽  
Michael Chambliss ◽  
Philip C. Ursell
Keyword(s):  
Infective Endocarditis ◽  
Aortic Valve ◽  
Bicuspid Aortic Valve ◽  
Trisomy 21 ◽  
Aortic Wall ◽  
Febrile Illness ◽  
Valve Leaflet ◽  
Sinus Of Valsalva ◽  
Sinus Of Valsalva Aneurysm

A 19-month-old girl with trisomy 21 and a congenitally bicuspid aortic valve died following a short febrile illness. Autopsy disclosed pericarditis, epimyocardial abscess, infective endocarditis, and a sinus of Valsalva aneurysm. Microscopy demonstrated continuity between the aortic wall and valve leaflet, consistent with an acquired aneurysm. Abnormal hemodynamics associated with the valve malformation likely facilitated endocarditis.

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