scholarly journals Analysis of inorganic ions in gingival crevicular fluid as indicators of periodontal disease activity: A clinico-biochemical study

2011 ◽  
Vol 2 (4) ◽  
pp. 278 ◽  
Author(s):  
AratiC Koregol ◽  
ShobhaP More ◽  
Sangamesh Nainegali ◽  
Nagaraj Kalburgi ◽  
Siddharth Verma
Keyword(s):  
Periodontal Disease ◽  
Disease Activity ◽  
Gingival Crevicular Fluid ◽  
Biochemical Study ◽  
Inorganic Ions ◽  
Crevicular Fluid

scholarly journals Comparative analysis of gingival crevicular fluid neopterin levels in health and periodontal disease: A biochemical study

2013 ◽  
Vol 24 (5) ◽  
pp. 582 ◽  
Author(s):  
Radhika Arjunkumar ◽  
Uma Sudhakar ◽  
Puthur Jayakumar ◽  
Lalitha Arunachalam ◽  
Snophia Suresh ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Periodontal Disease ◽  
Gingival Crevicular Fluid ◽  
Biochemical Study ◽  
Crevicular Fluid

scholarly journals Phospholipase A2Activity in Gingival Crevicular Fluid from Patients with Periodontal Disease: A possible Marker of Disease Activity

1994 ◽  
Vol 3 (1) ◽  
pp. 17-21 ◽  
Author(s):  
H. Ishida ◽  
H. Shinohara ◽  
T. Nagata ◽  
S. Nishikawa ◽  
Y. Wakano
Keyword(s):  
Enzyme Activity ◽  
Periodontal Disease ◽  
Disease Activity ◽  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Phospholipase A ◽  
Bleeding On Probing ◽  
Before And After ◽  
Crevicular Fluid

The activity of phospholipase A2in human gingival crevicular fluid (GCF) associated with periodontal disease was demonstrated. Based upon the presence or absence of bleeding on probing (BOP), which is a marker for the disease activity, there were higher levels of the enzyme activity in BOP positive, than in negative sites. When the BOP positive sites became negative after periodontal therapy, the enzyme activity decreased dramatically to almost undetectable levels. There were no significant differences between the activity before and after treatment when the BOP positive sites remained unchanged. These results suggest that the activity in GCF reflects periodontal disease conditions and that it can be used as a marker for disease activity.

Salivary Diagnosis - Clinical Uses in Assessing Oral Inflammation

2017 ◽  
Vol 68 (6) ◽  
pp. 1201-1204 ◽  
Author(s):  
Iulia Ioana Stanescu ◽  
Alexandra Totan ◽  
Florentina Rus ◽  
Daniela Miricescu ◽  
Brandusa Mocanu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Periodontal Disease ◽  
Gingival Crevicular Fluid ◽  
Oxidative Stress Marker ◽  
Clinical Settings ◽  
Tissue Destruction ◽  
Whole Saliva ◽  
Oral Inflammation ◽  
Positive Correlations ◽  
Crevicular Fluid

The past decades demonstrated that saliva and its components represent a remarkable diagnosis fluid with valuable clinical uses for both oral and systemic diseases. At the same time it is well established that oxidative stress is involved in a wide number of pathologies, including periodontitis. The specific aim of the present study which included 50 subjects is to determine if saliva can be used in clinical settings to correlate oxidative stress and tissue destruction markers with the severity of periodontal disease. An important oxidative stress marker - 8-hydroxydesoxyguanosine (8-OHdG) and a collagen degradation marker - beta-crosslaps (b-CTX) were quantified in both saliva and gingival crevicular fluid (GCF) using ELISA kits and were found to be significantly increased in the chronic periodontitis group when compared to respective controls (p[0.05). At the same time positive correlations were observed between whole saliva and gingival crevicular fluid (p[0.05). Significant correlations were also determined between GCF and salivary markers and clinical parameters of periodontal disease. Present results demonstrate that saliva and its components can successfully be used in clinical settings and represents a reliable tool for assessing periodontal disease severity.

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