Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix receptor interactions

VivekK Gupta; Mehdi Mirzaei; Liting Deng; PaulA Haynes; Yunqi Wu; Ardeshir Amirkhani; KarthikShantharam Kamath; JemmaX Wu; Kanishka Pushpitha; Veer Gupta; Stuart Graham

doi:10.4103/1673-5374.282261

Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix receptor interactions

Neural Regeneration Research ◽

10.4103/1673-5374.282261 ◽

2020 ◽

Vol 15 (11) ◽

pp. 2131

Author(s):

VivekK Gupta ◽

Mehdi Mirzaei ◽

Liting Deng ◽

PaulA Haynes ◽

Yunqi Wu ◽

...

Keyword(s):

Extracellular Matrix ◽

Growth Factor ◽

Amyloid Beta ◽

Neuronal Cells ◽

Amyloid Beta Peptide ◽

Insulin Like Growth Factor ◽

Beta Peptide ◽

Receptor Interactions ◽

Human Neuronal Cells

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The extracellular matrix enriched with membrane metalloendopeptidase and insulin‐degrading enzyme suppresses the deposition of amyloid‐beta peptide in Alzheimer's disease cell models

Journal of Tissue Engineering and Regenerative Medicine ◽

10.1002/term.2906 ◽

2019 ◽

Vol 13 (10) ◽

pp. 1759-1769 ◽

Cited By ~ 1

Author(s):

Shumang Zhang ◽

Tongqian Xiao ◽

Yanzhen Yu ◽

Yong Qiao ◽

Zhongjuan Xu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Extracellular Matrix ◽

Amyloid Beta ◽

Amyloid Beta Peptide ◽

Cell Models ◽

Insulin Degrading Enzyme ◽

Degrading Enzyme ◽

Beta Peptide ◽

Disease Cell

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Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type-1 insulin-like growth factor receptors in neuronal cells

Aging Cell ◽

10.1111/acel.12684 ◽

2017 ◽

Vol 17 (1) ◽

pp. e12684 ◽

Cited By ~ 13

Author(s):

Stefania Zimbone ◽

Irene Monaco ◽

Fiorenza Gianì ◽

Giuseppe Pandini ◽

Agata G. Copani ◽

...

Keyword(s):

Growth Factor ◽

Amyloid Beta ◽

Neuronal Cells ◽

Cyclic Adenosine Monophosphate ◽

Adenosine Monophosphate ◽

Insulin Like Growth Factor ◽

Response Element ◽

Protein Functions ◽

Element Binding Protein

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Pro-apoptotic signaling in neuronal cells following iron and amyloid beta peptide neurotoxicity

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2003.01831.x ◽

2004 ◽

Vol 86 (1) ◽

pp. 114-125 ◽

Cited By ~ 34

Author(s):

Faina Kuperstein ◽

Ephraim Yavin

Keyword(s):

Amyloid Beta ◽

Neuronal Cells ◽

Amyloid Beta Peptide ◽

Apoptotic Signaling ◽

Beta Peptide

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Effects Amyloid Beta Peptide on the Inflammatory Response in Neuronal Cells

KSBB Journal ◽

10.7841/ksbbj.2013.28.4.230 ◽

2013 ◽

Vol 28 (4) ◽

pp. 230-237

Author(s):

Seon-A Jang ◽

Hyun Jung Koo ◽

Se Chan Kang ◽

Eun-Hwa Sohn ◽

Seung Namkoong

Keyword(s):

Inflammatory Response ◽

Amyloid Beta ◽

Neuronal Cells ◽

Amyloid Beta Peptide ◽

Beta Peptide

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Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2008.01.033 ◽

2008 ◽

Vol 40 (9) ◽

pp. 1901-1917 ◽

Cited By ~ 19

Author(s):

Katherine A. Price ◽

Gulay Filiz ◽

Aphrodite Caragounis ◽

Tai Du ◽

Katrina M. Laughton ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Amyloid Beta ◽

Growth Factor Receptor ◽

Amyloid Beta Peptide ◽

Beta Peptide ◽

Epidermal Growth ◽

Metal Ligand

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Faculty Opinions recommendation of Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108064.564046 ◽

2008 ◽

Author(s):

Volker Haucke

Keyword(s):

Amyloid Beta ◽

Amyloid Beta Peptide ◽

Beta Peptide

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Faculty Opinions recommendation of Stabilization of a beta-hairpin in monomeric Alzheimer's amyloid-beta peptide inhibits amyloid formation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108040.572412 ◽

2008 ◽

Author(s):

Mitsuhiko Ikura

Keyword(s):

Amyloid Beta ◽

Amyloid Beta Peptide ◽

Amyloid Formation ◽

Beta Peptide ◽

Beta Hairpin

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Faculty Opinions recommendation of The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1148227.620383 ◽

2009 ◽

Author(s):

Joël Bockaert

Keyword(s):

G Protein ◽

Amyloid Beta ◽

Amyloid Beta Peptide ◽

G Protein Coupled Receptor ◽

Beta Peptide ◽

G Protein Coupled

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Faculty Opinions recommendation of T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-beta peptide.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1160908.622339 ◽

2009 ◽

Author(s):

Jerry Buccafusco ◽

Scott Webster

Keyword(s):

Spatial Memory ◽

Amyloid Beta ◽

Adult Neurogenesis ◽

Amyloid Beta Peptide ◽

Beta Peptide

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Faculty Opinions recommendation of Multiple mechanisms of iron-induced amyloid beta-peptide accumulation in SHSY5Y cells: protective action of negletein.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726187705.793515192 ◽

2016 ◽

Author(s):

Michael Aschner

Keyword(s):

Amyloid Beta ◽

Protective Action ◽

Amyloid Beta Peptide ◽

Beta Peptide

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