scholarly journals Sequential organ failure assessment score as prognostic marker in critically ill patients in a tertiary care intensive care unit

2013 ◽  
Vol 3 (3) ◽  
pp. 155 ◽  
Author(s):  
ZubinD Sharma ◽  
Charan Bale ◽  
ArjunL Kakrani ◽  
VarshaS Dabadghao
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Sequential Organ Failure Assessment ◽  
Organ Failure ◽  
Critically Ill ◽  
Prognostic Marker ◽  
Critically Ill Patients ◽  
Tertiary Care ◽  
Assessment Score ◽  
Failure Assessment

Evaluation of qSOFA as a Predictor of Mortality Among ICU Patients With Positive Clinical Cultures—A Retrospective Cohort Study

2019 ◽  
Vol 35 (11) ◽  
pp. 1278-1284
Author(s):  
Barry Kelly ◽  
Johann Patlak ◽  
Shahzad Shaefi ◽  
Dustin Boone ◽  
Ariel Mueller ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Hospital Mortality ◽  
Sequential Organ Failure Assessment ◽  
Organ Failure ◽  
Retrospective Cohort ◽  
Primary Outcome ◽  
Assessment Score ◽  
Failure Assessment ◽  
Discriminative Value

Objective: To compare the discriminative value of the quick-sequential organ failure assessment score (qSOFA) to SOFA in a critically ill population, in which a microbial pathogen was isolated within 48 hours of admission to intensive care. Design: Retrospective cohort study. Setting: Academic tertiary referral center from July 2008 to June 2017. Patients: Hospitalized patients admitted to intensive care unit. Interventions: None. Measurements and Main Results: The primary outcome was in-hospital mortality for all patients with confirmed positive microbiological cultures within 48 hours of admission to intensive care unit (ICU). Subgroup analysis was performed on patients with pathogenic bacteremia or positive cultures in cerebrospinal fluid. Of the 11 415 patients analyzed with positive microbiology specimens within 48 hours of admission, 2933 (25.7%) had a qSOFA ≥2. Of these, 16.6% reached the primary outcome of in-hospital mortality. Unsurprisingly, the discriminative value of qSOFA on admission was significantly worse than that of SOFA (0.73 vs 0.76; P = .0004), despite observing a significant association between qSOFA category and in-hospital mortality ( P < .0001). In secondary analyses, similar observations were found using qSOFA within 6 and 24 hours of ICU admission. When analysis was focused on patients with pathogenic bacteremia or positive cerebrospinal fluid (CSF) cultures (n = 1646), there was no significant difference between the discriminative value of qSOFA and SOFA (0.75 vs 0.78; P = .17). Conclusions: Quick-sequential organ failure assessment score at admission was not superior to SOFA in predicting in-hospital mortality in patients with positive clinical cultures within 48 hours of admission to ICU. Quick-sequential organ failure assessment score at admission to the ICU was associated with mortality and showed reasonable calibration and discrimination. When the analysis was focused on patients with pathogenic bacteremia or positive CSF cultures, qSOFA performed similarly to SOFA in discriminatory those who will die from sepsis.

SERIAL EVALUATION OF THE SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE TO PREDICT OUTCOME IN CRITICALLY ILL PATIENTS.

2006 ◽  
Vol 34 ◽  
pp. A142
Author(s):  
Margarida Câmara ◽  
Ofélia Afonso ◽  
António Táboas ◽  
J L Brandão ◽  
Álvaro Silva ◽  
...  
Keyword(s):  
Sequential Organ Failure Assessment ◽  
Organ Failure ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Assessment Score ◽  
Failure Assessment ◽  
Serial Evaluation

scholarly journals The correlation of the Sequential Organ Failure Assessment score with intensive care unit outcome

Critical Care ◽  
2007 ◽  
Vol 11 (Suppl 2) ◽  
pp. P462
Author(s):  
I Ketchley ◽  
A Theodoraki ◽  
T Reynolds ◽  
A Tillyard ◽  
R Lawson ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Sequential Organ Failure Assessment ◽  
Organ Failure ◽  
Assessment Score ◽  
Failure Assessment

scholarly journals The Comparison between Sepsis 1.0 and Sepsis 3.0 in Database of Severe Infection in Critical Illness: A Retrospective Study

2019 ◽  
Author(s):  
Wei Zhang ◽  
Yan Zheng ◽  
Juan Gu ◽  
Yan Kang
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Hospital Mortality ◽  
Sequential Organ Failure Assessment ◽  
Critically Ill ◽  
Predictive Validity ◽  
Critically Ill Patients ◽  
Severe Infection ◽  
Suspected Infection ◽  
Failure Assessment

Abstract Objective To compared the Sepsis 1.0 criterial with the Sepsis 3.0 criteria predict the efficacy of all-caused mortality of in-hospital in critically ill patients with severe infection. Design This is a retrospective and cohort study based on the database of severe infection. Setting A 48-bed general intensive care unit in affiliated hospital of University. Patients Critically ill patients with suspected infection based on the electronic health records from 1 January to 31 December, 2015. Interventions None. Measurements The variables of exposures included: quick sequential organ failure assessment (qSOFA), systemic inflammatory response syndrome (SIRS) score and sequential organ failure assessment (SOFA). Main outcomes and measures: for predictive validity, we found that the discrimination for hospital mortality was more common with sepsis than with uncomplicated infections. Results are reported as the area under the receiver operating characteristic curve (AUROC).Main Results In the primary cohort, 873 patients had suspected infection cohort (n=634), of whom 188 (29.7%) died; and with the non-infection cohort (n=239), 26 patients died (10.9%). Among intensive care unit (ICU) cases in the infection cohort, the predictive validity for hospital mortality was higher for Sepsis 3.0 (SOFA) criteria (AUROC=0.702; 95%CI, 0.665 −0.737; p≤0.01 for both) than for Sepsis 1.0 (SIRS) criteria (AUROC=0.533; 95% confidence interval [95%CI], 0.493−0.572). Conclusions In our study, we found the Sepsis 3.0 criteria is able to accurately predict the prognosis in critically ill patients with severe infection, and its predictive efficacy is superior to Sepsis 1.0 criteria.

Prognostic performance of pancreatic stone protein in critically ill patients with sepsis

2019 ◽  
Vol 13 (17) ◽  
pp. 1469-1480
Author(s):  
Luis García de Guadiana-Romualdo ◽  
María Dolores Albaladejo-Otón ◽  
Mario Berger ◽  
Enrique Jiménez-Santos ◽  
Roberto Jiménez-Sánchez ◽  
...  
Keyword(s):  
Sequential Organ Failure Assessment ◽  
Organ Failure ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Operating Characteristic ◽  
Pancreatic Stone ◽  
Assessment Score ◽  
Unit Management ◽  
Failure Assessment ◽  
Intensive Care Unit Management

Aim: To assess the prognostic value for 28-day mortality of PSP in critically ill patients with sepsis. Material & methods: 122 consecutive patients with sepsis were enrolled in this study. Blood samples were collected on admission and day 2. Results: On admission, the combination of PSP and lactate achieved an area under the receiver operating characteristic (AUC-ROC) of 0.796, similar to sequential organ failure assessment score alone (AUC-ROC: 0.826). On day 2, PSP was the biomarker with the highest performance (AUC-ROC: 0.844), although lower (p = 0.041) than sequential organ failure assessment score (AUC-ROC: 0.923). Conclusion: The combination of PSP and lactate and PSP alone, on day 2, have a good performance for prognosis of 28-day mortality and could help to identify patients who may benefit most from tailored intensive care unit management.

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