scholarly journals Expression of calretinin and cytokeratin 19 in radicular cyst, dentigerous cyst, odontogenickerato cyst, and ameloblastoma

2016 ◽  
Vol 5 (2) ◽  
pp. 118 ◽  
Author(s):  
Aesha Imran ◽  
Kannan Ranganathan ◽  
Uma DeviK Rao ◽  
Elzibeth Joshua ◽  
Rooban Thavarajah
2018 ◽  
Vol 61 (1) ◽  
pp. 17-21
Author(s):  
Zohreh Jaafari-Ashkavandi ◽  
Ahmad Alipour Tuyeh ◽  
Sepideh Assar

CDC7 is a serine/threonine kinase which has an essential role in initiation of DNA proliferation and S phase. It increases the invasion and proliferation in many pathologic lesions. This study aimed to evaluate the expression of CDC7 in the most common odontogenic cysts. We evaluated 17 dentigerous cysts, 18 odontogenic keratocysts (OKC) and 13 radicular cysts immunohistochemically. The mean expression of CDC7 was analyzed using ANOVA and Post-HOC methods. All specimens revealed CDC7 expression. Higher expression of CDC7 in OKC and radicular cyst was shown in comparison to dentigerous cyst (P < 0.001), while radicular cyst and OKC groups showed no difference in CDC7 expression (P = 0.738). The high expression of CDC7 in OKC suggests that this protein could be related to the higher proliferation rate and invasiveness of OKC. On the other hand, the higher CDC7 expression in radicular cyst may simply be related to inflammation as this cyst is neither aggressive nor invasive.


2021 ◽  
Vol 12 (5) ◽  
pp. 270-274
Author(s):  
Yuvraj Parmar ◽  
Naman Patel ◽  
Vivek Tarsariya ◽  
Neelkunvar Maharaja ◽  
Vidhi Parmar

Author(s):  
Premkumar ◽  
Maya Ramesh ◽  
Mathew Jacob ◽  
B Sekar ◽  
K. Indrapridharshini ◽  
...  

Author(s):  
Yadira V. Boza Oreamuno DDS, MSc ◽  
Andrea López Soto DDS, MSc

Bone lesions of the jaws have their origin from odontogenic and non-odontogenic structures. They can be benign or malignant, asymptomatic, they can be located around the root of the tooth, around the crown and in the interradicular area or they may not be related to the teeth. OBJECTIVE: to determine the frequency of the different bone lesions and the concordance between the clinical and histopathological diagnosis, in the clinical internship of the Faculty of Dentistry of the University of Costa Rica (UCR). METHODOLOGY: retrospective study of bone lesions recovered from the biopsy archive of the Faculty of Dentistry of the UCR from 2008 to 2015. Information on sex, age, location of the lesion, clinical diagnosis and diagnosis were evaluated and described. The agreement between the clinical and histopathological diagnosis was verified by the Kappa test. RESULTS: The 77 cases of oral bone lesions preferentially affected men 53.8% (n=41), the average age was 34.7 years (s.d.±19.6) and with lesions predominantly located in the posterior jaw 36.4% (n=28) and anterior maxilla 35.1% (n=27). Odontogenic cysts (OC) 42.9% (n=33), non-specific or unclassified diagnosis 28.6% (n=22) and inflammatory lesions of pulp and periapical origin 14.2% (n=11). TOs accounted for 7.8% (n=6) of the lesions. The four most predominant lesions were the radicular cyst, nonspecific diagnosis, dentigerous cyst and periapical granuloma. Concordance with the first diagnostic hypothesis was presented in 24 (31.2%) cases, the value of Kappa was 0.274 (discrete concordance) and 20.8% without clinical diagnosis only a description of the lesion. CONCLUSIONS: The OC were the predominant; being individually the radicular cyst the most frequent lesion. The clinical and histopathological concordance was discrete.


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