scholarly journals To compare the effects of multiple sessions of Hyperbaric Oxygen Therapy in neurological improvement in head injury patients: A prospective randomized trial

2015 ◽  
Vol 02 (02) ◽  
pp. 110-113 ◽  
Author(s):  
Amlendu Yadav ◽  
Mridula Pawar ◽  
Rakesh Garg ◽  
Neerja Banerjee

Abstract Introduction: Hyperbaric oxygen therapy (HBOT) is used to improve functional outcome following brain injuries. Different number of sessions of HBOT have been reported but the frequency of HBOT sessions in head injured patients has not been standardized. We planned this prospective randomized study with an aim to compare the neurological effects of 10, 20 and 30 sessions of HBOT in the head injured patients. Materials and Methods: After review board approval, this study was conducted in 60 head injury patients with Glasgow Coma Scale (GCS) score ≤ 9. All patients were resuscitated, stabilized and received neurological care according to institutional protocol. Patients were randomly allotted to–Group H10 (n-20)–which received 10 sittings of HBOT, Group H20 (n-20)–which received 20 sittings of HBOT, Group H30 (n-30)–which received 30 sittings of HBOT. GCS score was recorded after every 10 sittings and at 30 days from initiation of HBOT. Improvement Global rating and Glasgow outcome scale (GOS) were recorded after 30 days. Results: The maximum improvement in GCS scores was seen in group H30. The difference in the average improvement global rating scale was significant between group H10 and group H20, between group H10 and group H30 but was comparable between groups H20 and H30. The GOS was better after 30 sessions as compared to 10 sessions. Patients of all groups showed improvement in spasticity but group H30 showed a maximum improvement. Conclusion: A minimum of 30 HBOT sessions should be considered in head injury patients to show improvement with HBOT. Progressive improvement in GCS scores, GOS, spasticity, mood swings was better seen with increased number of HBOT sessions.

1997 ◽  
Vol 87 (2) ◽  
pp. 234-238 ◽  
Author(s):  
John N. K. Hsiang ◽  
Theresa Yeung ◽  
Ashley L. M. Yu ◽  
Wai S. Poon

✓ The generally accepted definition of mild head injury includes Glasgow Coma Scale (GCS) scores of 13 to 15. However, many studies have shown that there is a heterogeneous pathophysiology among patients with GCS scores in this range. The current definition of mild head injury is misleading because patients classified in this category can have severe sequelae. Therefore, a prospective study of 1360 head-injured patients with GCS scores ranging from 13 to 15 who were admitted to the neurosurgery service during 1994 and 1995 was undertaken to modify the current definition of mild head injury. Data regarding patients' age, sex, GCS score, radiographic findings, neurosurgical intervention, and 6-month outcome were collected and analyzed. The results of this study showed that patients with lower GCS scores tended to have suffered more serious injury. There was a statistically significant trend across GCS scores for percentage of patients with positive acute radiographic findings, percentage receiving neurosurgical interventions, and percentage with poor outcome. The presence of postinjury vomiting did not correlate with findings of acute radiographic abnormalities. Based on the results of this study, the authors divided all head-injured patients with GCS scores ranging from 13 to 15 into mild head injury and high-risk mild head injury groups. Mild head injury is defined as a GCS score of 15 without acute radiographic abnormalities, whereas high-risk mild head injury is defined as GCS scores of 13 or 14, or a GCS score of 15 with acute radiographic abnormalities. This more precise definition of mild head injury is simple to use and may help avoid the confusion caused by the current classification.


2012 ◽  
Vol 7 (1) ◽  
pp. 4 ◽  
Author(s):  
Advait Prakash ◽  
SandeshV Parelkar ◽  
SanjayN Oak ◽  
RahulK Gupta ◽  
BeejalV Sanghvi ◽  
...  

2014 ◽  
Vol 3 ◽  
pp. 14
Author(s):  
Shiqiang Wang

<p><strong>Objective: </strong>To review and analyze the clinical effect of hyperbaric oxygen therapy in the treatment of craniocerebral trauma, and to provide reference for the treatment of craniocerebral trauma. <strong>Method: </strong>From January 2009 to April 2014, we treated 287 cases of patients with craniocerebral trauma, on the basis of conventional treatment, the use of hyperbaric oxygen therapy and assessment for therapeutic effect. <strong>Results</strong><strong>: </strong>After hyperbaric oxygen therapy, patients with GCS score and GOS levels were significantly improved, compared with before treatment, the difference was statistically significant (<em>p</em> &lt; 0.05); effect of the treatment of patients with 2−3 courses of treatment was better than patients receive more than 3 courses of treatment (<em>p</em> &lt; 0.05). <strong>Conclusion: </strong>Hyperbaric oxygen in the treatment of craniocerebral trauma can effectively improve patient’s symptoms and signs, there are helpful in the recovery of the body function of patients. Hyperbaric oxygen treatment should be carry out as soon as possible with appropriate extending the duration of treatment, as well as reduce the severe disability, death and sequela.</p>


2004 ◽  
Vol 21 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Eilam Palzur ◽  
Eugene Vlodavsky ◽  
Hani Mulla ◽  
Ran Arieli ◽  
Moshe Feinsod ◽  
...  

Biomeditsina ◽  
2020 ◽  
pp. 39-46
Author(s):  
A. S. Samoilov ◽  
Yu. D. Udalov ◽  
M. V. Sheyanov ◽  
A. V. Gholinsky ◽  
A. B. Litvinenko

This communication presents the experience of using mobile pressure chambers in patients with the confi rmed novel coronavirus infection in hospital settings. The obtained preliminary results indicate positive antihypoxic effects of hyperbaric oxygen therapy (HBO) applied in the form of increased saturation. After a session of HBO, patients demonstrated an increase in the oxygen saturation of capillary blood hemoglobin at the average level of 3.71 points. Differences between SatO2 levels prior to and following HBO treatment were signifi cant in the CT2, CT3 and CT4 groups (p0.05). As expected, the effi cacy of HBO in terms of the oxygen saturation of capillary blood hemoglobin was the greatest in the patient groups showing pronounced clinical and radiological changes in the lungs.


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