scholarly journals Clinical Observation of Hyperbaric Oxygen Therapy in Patients with Craniocerebral Trauma

2014 ◽  
Vol 3 ◽  
pp. 14
Author(s):  
Shiqiang Wang
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Craniocerebral Trauma ◽  
The Body ◽  
Duration Of Treatment ◽  
The Difference ◽  
Gcs Score ◽  
Symptoms And Signs ◽  
Better Than

<p><strong>Objective: </strong>To review and analyze the clinical effect of hyperbaric oxygen therapy in the treatment of craniocerebral trauma, and to provide reference for the treatment of craniocerebral trauma. <strong>Method: </strong>From January 2009 to April 2014, we treated 287 cases of patients with craniocerebral trauma, on the basis of conventional treatment, the use of hyperbaric oxygen therapy and assessment for therapeutic effect. <strong>Results</strong><strong>: </strong>After hyperbaric oxygen therapy, patients with GCS score and GOS levels were significantly improved, compared with before treatment, the difference was statistically significant (<em>p</em> &lt; 0.05); effect of the treatment of patients with 2−3 courses of treatment was better than patients receive more than 3 courses of treatment (<em>p</em> &lt; 0.05). <strong>Conclusion: </strong>Hyperbaric oxygen in the treatment of craniocerebral trauma can effectively improve patient’s symptoms and signs, there are helpful in the recovery of the body function of patients. Hyperbaric oxygen treatment should be carry out as soon as possible with appropriate extending the duration of treatment, as well as reduce the severe disability, death and sequela.</p>

scholarly journals Adjunctive Hyperbaric Oxygen Therapy in Refractory Crohn’s Disease: An Observational Study

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Marley R. Feitosa ◽  
Rogério S. Parra ◽  
Vanessa F. Machado ◽  
Gustavo N. Vilar ◽  
Jussara C. Aquino ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Optimal Number ◽  
Complete Healing ◽  
Duration Of Treatment ◽  
Treatment Regimens ◽  
Incomplete Healing

Background and Aims. Patients may experience complications of Crohn’s disease (CD) even when treated with optimal medical therapy strategies. Previous data have shown the efficacy of hyperbaric oxygen therapy (HBOT) in the management of complicated CD. However, there is no consensus regarding the optimal number of sessions or duration of treatment regimens. The aim of the present study was to investigate the efficacy of HBOT in CD patients who were refractory to conventional medical management. Methods. This study included patients who underwent HBOT for the treatment of the following complications: perianal fistulizing Crohn’s disease (pCD), enterocutaneous fistulas (ECF), or pyoderma gangrenosum (PG). Complete healing was defined as the closure of external orifice and the absence of active draining (in pCD), complete wound healing (in PG), and granulation or complete wound epithelialization with no enteric draining (in ECF). The persistence of draining and the absence of wound granulation were defined as incomplete healing. Results. Forty patients were included. The mean CD duration was 10.6 ± 5.8 years. pCD comprised most of the included patients (25/62.5%), followed by ECF ( n = 13 / 32.5 % ) and PG ( n = 6 / 15 % ). In two patients (5%), a combination of ECF and PG was diagnosed, and in one patient (2.5%), all three complications were observed. A total of 32 patients (82.5%) had complete healing. Patients with PG had the highest healing rates (100%), followed by those with ECF (84.6%) and pCD (80%). Conclusions. Adjunctive HBO was associated with significant healing rates for CD-associated complications such as pCD, ECF, and PG.

scholarly journals The Effect of Hyperbaric Oxygen Therapy to the Amount of Lymphocytes in Oral Candidiasis Immunosuppressed Model

DENTA ◽  
2019 ◽  
Vol 12 (2) ◽  
pp. 36
Author(s):  
Agni Febrina Pargaputri ◽  
Dwi Andriani
Keyword(s):  
Immune System ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Wistar Rats ◽  
Oxygen Therapy ◽  
Oral Candidiasis ◽  
Control Group ◽  
Control Group Design ◽  
Significant Difference ◽  
The Difference

<p><strong><em> </em></strong></p><p><strong><em>Background: </em></strong><em>Oral candidiasis generally caused by Candida albicans with prevalence of 30-50%. C. Albicans proliferation in the oral cavity was canducted by decreasing immune system of the host. Lymphocytes activation in immune system happened when there is a contact between host cell with cell wall of C. albicans as a result of C. albicans antigen. One of therapy to suppress the Candida infection sistemically is by giving hyperbaric oxygen therapy. <strong>Purpose: </strong>To determine the effects of giving hyperbaric oxygen therapy to the amount of lymphocytes in oral candidiasis immunosuppressed models. <strong>Methods:</strong> This research was post test only control group design. We used 12 wistar rats which were divided into 3 groups(n=4/3): K-(normal/ healthy wistar rats), K+(oral candidiasis immunosuppressed wistar rats), P1(oral candidiasis immunosuppressed wistar rats which were given hyperbaric oxygen therapy 5 days). K+ and P1 groups were immunosuppressed by giving dexamethasone 0,5mg/day/rat orally for 14 days, added with tetrasiklin 1 mg/day/rat. On the 3rd day immunosuppression, the rats were inducted with C.albicans smeared in the dorsum linguae once every two days for 12 days. <strong>Results:</strong> The data were analyzed with one way Anova test and showed significant difference among groups (p&lt;0,05). To show the difference between each groups we used LSD test and showed significant difference (p&lt;0,05) between K+ compared with P1, and K+ compared with K-. <strong>Conclusion:</strong> Hyperbaric oxygen therapy gives effect to the amount of lymphocytes in oral candidiasis immunosuppressed models.</em></p><p><em> </em><strong><em>Keywords:</em></strong><em> Oral candidiasis, immunosuppressed, hyperbaric oxygen therapy, lymphocytes</em></p><p> <strong><em>Correspondence</em></strong><strong><em>: </em></strong><em>Agni Febrina Pargaputri</em><em>, Departmen</em><em>t of</em><em> Oral </em><em>Biology </em><em>F</em><em>aculty of</em><em> </em><em>Dentistry</em><em>, Jl. Arif Rahman Hakim 150, Surabaya, Indonesia. </em><em>Phone:</em><em> 031-5945864, fax: 031-5912191, Email: </em><em><span style="text-decoration: underline;">agni.febrina</span></em><em><span style="text-decoration: underline;">@hangtuah.ac.id</span></em></p><p> </p>

Hyperbaric Oxygen Therapy and Its Suitability as an Adjuvant for Treatment of Covid-19 Patients: A Review

2021 ◽  
Vol 12 (4) ◽  
pp. 2548-2556
Author(s):  
Sameera Dawar ◽  
Meena Jain
Keyword(s):  
Mechanical Ventilation ◽  
Oxygen Saturation ◽  
Hyperbaric Oxygen ◽  
Basic Principle ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Delivery ◽  
Atmospheric Pressure ◽  
Oxygen Therapy ◽  
Tissue Oxygenation ◽  
The Body

The outbreak of the SARS CoV2 ' pandemic' is believed to have originated in Wuhan in 2019 as a spread from bats to humans. It is a highly communicable infection-causing rapid human to human transmission of the virus by virtue of its infectious and nature. The virus has affected millions of people worldwide, with numbers still rising with each passing day. Depleting oxygen saturation levels is amongst the prime concerns in the majority of infected patients. Nasal prongs, face masks, mechanical ventilation and membrane (ECMO) are the commonly used modes of oxygen delivery in such patients. These methods though mostly successful, at times fail to restore the depleting oxygen levels to normal. oxygen therapy (HBOT) involves the administration of 100% O2 in a special chamber whose pressure is maintained at a level greater than 1 ATP. The main purpose for raising the pressure within the chamber is that as the atmospheric pressure increases, the saturation levels of oxygen in the blood also increase, which eventually result in increased overall tissue oxygenation. This article provides a systematic and wholesome review on the basic principle of oxygen therapy, its effects on the body at a microscopic and macroscopic level, its various uses and its suitability as an for the treatment of select COVID-19 infected patients.

scholarly journals Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia

2021 ◽  
Vol 2 ◽  
Author(s):  
Priya Balasubramanian ◽  
Jordan Delfavero ◽  
Adam Nyul-Toth ◽  
Amber Tarantini ◽  
Rafal Gulej ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Vascular Cognitive Impairment ◽  
The Body ◽  
World Population ◽  
Age Related

Growing life expectancy will contribute to the on-going shift towards a world population increasingly comprised of elderly individuals. This demographic shift is associated with a rising prevalence of age-related diseases, among all age-related pathologies it has become crucial to understand the age-associated cognitive changes that remain a major risk factor for the development of vascular cognitive impairment and dementia (VCID). Furthermore, age-related Alzheimer’s disease and other neurogenerative diseases with vascular etiology are the most prominent contributing factors for the loss of cognitive function observed in aging. Hyperbaric Oxygen Therapy (HBOT) achieves physiologic effects by increasing oxygen tension (PO2), raising oxygen tissue levels, decreasing intracranial pressure and relieving cerebral edema. Many of the beneficial effects of HBOT exert their protective effects at the level of the microcirculation. Furthermore, the microcirculation’s exquisite pervasive presence across every tissue in the body, renders it uniquely able to influence the local environment of most tissues and organs, including the brain. As such, treatments aimed at restoring aging-induced functional and structural alterations of the cerebral microcirculation may potentially contribute to the amelioration of a range of age-related pathologies including vascular cognitive impairment, Alzheimer’s disease, and vascular dementias. Despite the presented evidence, the efficacy and safety of HBOT for the treatment of age-related vascular cognitive impairment and dementia remains understudied. The present review aims to examine the existing evidence indicative of a potential therapeutic role for HBOT-induced hyperoxia against age-related cerebromicrovascular pathologies contributing to cognitive impairment, dementia and decreased healthspan in the elderly.

scholarly journals Parameters of the oxidative-reduction system of the homeostasis in female transplant patients with tumors of the reproductive system treated with hyperbaric oxygen therapy

2019 ◽  
Vol 11 (4) ◽  
pp. 290-300
Author(s):  
A. V. Babkina ◽  
M. Sh. Khubutiya ◽  
O. A. Levina ◽  
A. K. Evseev ◽  
A. K. Shabanov ◽  
...  
Keyword(s):  
Hyperbaric Oxygen ◽  
Postoperative Period ◽  
Reproductive System ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
The Body ◽  
Antioxidant Systems ◽  
Complex Treatment ◽  
Transplant Patients

Introduction. Studies on the effects of hyperbaric oxygenation have often been represented as animal model experiments. Currently, the number of studies on the use of hyperbaric oxygen therapy in the post-transplant period in humans is growing. The need in investigating the efficacy of hyperbaric oxygen therapy in the postoperative period in female transplant patient with tumors of the reproductive system is dictated by time.The aim of the study was to evaluate the efficacy of hyperbaric oxygen therapy in the complex treatment of transplant patients at an early stage of the postoperative period.Material and methods. We have studied the course of an early postoperative period in 8 female transplant patients with reproductive system tumors treated in N.V. Sklifosovsky Research Institute for Emergency Medicine, using hyperbaric oxygenation. The hyperbaric oxygen therapy sessions were provided in a single-patient hyperbaric chamber at 1.2–1.6 ATA for 40 minutes. The status of the redox homeostasis system was assessed based on the data of the platinum electrode open circuit potential measured in blood plasma by using the potentiometric method; and the blood plasma antioxidant activity was assessed by cyclic voltammetry.Results. The analysis of the results showed that there was a direct relationship indicating the positive effect of hyperbaric oxygen therapy on the balance status of the pro- and antioxidant systems of the body, and on the improvement of blood counts.Conclusion. The early inclusion of hyperbaric oxygen therapy in the complex treatment of transplant patients with tumors of the reproductive system contributes to a more rapid recovery of pro- and antioxidant systems of the body, blood counts.

scholarly journals Experiences of patients with pelvic radiation injuries after cancer treatment undergoing hyperbaric oxygen therapy: A phenomenological-hermeneutical study

2021 ◽  
pp. 205715852199440
Author(s):  
Grete K. Velure ◽  
Bernd Müller ◽  
May Aa. Hauken
Keyword(s):  
Cancer Survivors ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Relevant Information ◽  
Pelvic Cancer ◽  
After Cancer ◽  
Treatment Alternatives ◽  
Depth Interviews ◽  
Better Than

Radiotherapy of pelvic cancers may cause severe tissue injuries, and hyperbaric oxygen therapy (HBOT) is one of few treatment alternatives. As part of a longitudinal, mixed-methods study, this study’s aim was to explore pelvic cancer survivors’ experiences of undergoing such treatment. Using a phenomenological-hermeneutical design, in-depth interviews of 20 cancer survivors were conducted and analysed using systematic text condensation. This study is reported in accordance with COREQ. The informants’ experiences were identified as: Approaching an unknown world, From feeling worried to becoming familiar, A long-lasting treatment course, and The treatment course went better than expected. Despite information prior to the treatment, informants were worried about HBOT but were still motivated to try it. A combination of relevant information, clear routines, person-centred care, peer support, and limited side effects seem to be important factors for patients’ experiences of safety from this treatment.

Effect of hyperbaric oxygen therapy on the duration of treatment of spinal tuberculosis

2009 ◽  
Vol 16 (12) ◽  
pp. 1572-1577 ◽  
Author(s):  
Kıvanç Topuz ◽  
Ahmet Murat Kutlay ◽  
Hakan Şimşek ◽  
Ahmet Çolak ◽  
Serdar Kaya ◽  
...  
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Spinal Tuberculosis ◽  
Duration Of Treatment

scholarly journals Oxigenoterapia hiperbárica como tratamento adjuvante para feridas: estudo de prevalência

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Camila Lopes Liandro ◽  
Marcia Santos ◽  
Mônica De Almeida Carreiro ◽  
Karinne Cristinne da Silva Cunha ◽  
Danielle Galdino De Paula
Keyword(s):  
Diabetes Mellitus ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Medical Records ◽  
Oxygen Therapy ◽  
Statistical Significance ◽  
Care Plan ◽  
Linear Modeling ◽  
Duration Of Treatment ◽  
Cross Sectional

Objetivo: descrever a prevalência dos tipos de feridas com indicação para oxigenoterapia hiperbárica. Método: estudo transversal, quantitativo e retrospectivo. Foram analisados prontuários de pacientes atendidos no setor de medicina hiperbárica referentes ao período de janeiro a dezembro de 2015. Empregou-se estatística descritiva e analítica. Resultados: Nos 60 prontuários analisados foram prevalentes: idade entre 19-49 anos e 61-72 anos (ambas com 27,1%), sexo masculino (68,3%), Diabetes Mellitus (44,1%) e deiscência cirúrgica (20,3%). Pessoas com idade de 61-72 anos tiveram maior tempo de sessões (mediana = 40 sessões). A regressão por modelagem linear utilizando como preditor a variável tempo de tratamento pela doença, demonstrou significância estatística do tabagismo e doença hematológica.  Discussão: Os achados corroboram com estudos sobre a ocorrência de feridas. Conclusão: O estudo de prevalência poderá contribuir para a elaboração de um plano de cuidados de enfermagem individualizado ao portador de feridas que realizam tratamento no setor de oxigenoterapia hiperbárica.Descritores: Oxigenação hiperbárica; Ferimento e Lesões; Cicatrização; Prevalência; Enfermagem. Objective: Describe the prevalence of types of wounds indicated for hyperbaric oxygen therapy. Method: cross-sectional, quantitative and retrospective study. Were analyzed medical records of patients seen in the hyperbaric medicine sector for the period from January to December 2015. Descriptive and analytical statistics were used. Results: In the 60 medical records analyzed, the following were prevalent: age between 19-49 years and 61-72 years (both with 27,1%), male (68,3%), Diabetes Mellitus (44,1%) and surgical dehiscence (20,3%). People aged 61-72 years had longer sessions (median = 40 sessions). Regression by linear modeling using the variable duration of treatment for the disease as a predictor, demonstrated statistical significance of smoking and hematological disease. The findings corroborate with studies on the occurrence of wounds. Conclusion: The prevalence study may contribute to the development of an individualized nursing care plan for patients with wounds undergoing treatment in the hyperbaric oxygen therapy sector.Descriptors: Hyperbaric oxygenation; Wounds and Injuries;  Healing; Prevalence; Nursing. Objetivo: describir la prevalencia de los tipos de heridas indicadas para la oxigenoterapia hiperbárica. Método: estudio transversal, cuantitativo y retrospectivo. Se analizaron los registros médicos de pacientes atendidos en el sector de la medicina hiperbárica para el período de enero a diciembre de 2015. Se utilizaron estadísticas descriptivas y analíticas. Resultados: en los 60 registros médicos analizados, prevalecieron los siguientes: edad entre 19-49 años y 61-72 años (ambos con 27.1%), hombres (68.3%), diabetes mellitus (44.1%) y dehiscencia quirúrgica ( 20,3%). Las personas de 61 a 72 años tuvieron sesiones más largas (mediana = 40 sesiones). La regresión por modelado lineal utilizando la duración variable del tratamiento de la enfermedad como predictor, demostró la importancia estadística del tabaquismo y la enfermedad hematológica. Los hallazgos corroboran con los estudios sobre la aparición de heridas. Conclusión: El estudio de prevalencia puede contribuir al desarrollo de un plan de atención de enfermería individualizado para pacientes con heridas que reciben tratamiento en el sector de oxigenoterapia hiperbárica.Descriptores: Oxigenación hiperbárica; Heridas y Lesiones; Cicatrización; Prevalencia; Enfermería. 

scholarly journals To compare the effects of multiple sessions of Hyperbaric Oxygen Therapy in neurological improvement in head injury patients: A prospective randomized trial

2015 ◽  
Vol 02 (02) ◽  
pp. 110-113 ◽  
Author(s):  
Amlendu Yadav ◽  
Mridula Pawar ◽  
Rakesh Garg ◽  
Neerja Banerjee
Keyword(s):  
Head Injury ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Global Rating Scale ◽  
Global Rating ◽  
Head Injured ◽  
Maximum Improvement ◽  
Gcs Score ◽  
Injured Patients

Abstract Introduction: Hyperbaric oxygen therapy (HBOT) is used to improve functional outcome following brain injuries. Different number of sessions of HBOT have been reported but the frequency of HBOT sessions in head injured patients has not been standardized. We planned this prospective randomized study with an aim to compare the neurological effects of 10, 20 and 30 sessions of HBOT in the head injured patients. Materials and Methods: After review board approval, this study was conducted in 60 head injury patients with Glasgow Coma Scale (GCS) score ≤ 9. All patients were resuscitated, stabilized and received neurological care according to institutional protocol. Patients were randomly allotted to–Group H10 (n-20)–which received 10 sittings of HBOT, Group H20 (n-20)–which received 20 sittings of HBOT, Group H30 (n-30)–which received 30 sittings of HBOT. GCS score was recorded after every 10 sittings and at 30 days from initiation of HBOT. Improvement Global rating and Glasgow outcome scale (GOS) were recorded after 30 days. Results: The maximum improvement in GCS scores was seen in group H30. The difference in the average improvement global rating scale was significant between group H10 and group H20, between group H10 and group H30 but was comparable between groups H20 and H30. The GOS was better after 30 sessions as compared to 10 sessions. Patients of all groups showed improvement in spasticity but group H30 showed a maximum improvement. Conclusion: A minimum of 30 HBOT sessions should be considered in head injury patients to show improvement with HBOT. Progressive improvement in GCS scores, GOS, spasticity, mood swings was better seen with increased number of HBOT sessions.

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