scholarly journals The role of interferon-gamma and interferon-gamma receptor in tuberculosis and nontuberculous mycobacterial infections

2021 ◽  
Vol 10 (4) ◽  
pp. 349
Author(s):  
Poopak Farnia ◽  
Jalaledin Ghanavi ◽  
Parissa Farnia ◽  
AliAkbar Velayati
Keyword(s):  
Interferon Gamma ◽  
Mycobacterial Infections ◽  
Gamma Receptor

scholarly journals A case of recurrent herpes simplex 2 encephalitis, VZV reactivations, and dominant partial interferon-gamma-receptor-1 deficiency supports relevance of IFNgamma for antiviral defense in humans

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Julia Körholz ◽  
Nicole Richter ◽  
Jochen Schäfer ◽  
Catharina Schuetz ◽  
Joachim Roesler
Keyword(s):  
Herpes Simplex ◽  
Interferon Gamma ◽  
Viral Infections ◽  
Viral Disease ◽  
Antiviral Defense ◽  
Case Presentation ◽  
Gamma Receptor ◽  
Recurrent Herpes ◽  
Increased Susceptibility

Abstract Background Unlike infections with mycobacteria, reports of unusual viral infections in interferon-gamma-receptor (IFNγR) deficient patients are scarce. Therefore, discussion about increased susceptibility to viral infections in these patients is ongoing. Case presentation We describe a 51-year-old male with dominant partial interferon-gamma-receptor-1 (IFNγR1)-deficiency and recurrent Herpes simplex 2 meningoencephalitis as well as other viral reactivations since childhood. Conclusions This case further confirms an enhanced risk for viral disease in IFNγR-deficient patients and a role of interferon gamma for human antiviral defense.

Role of the macrophage-inducible C-type lectin Mincle in the lung host defense against mycobacterial infections in mice

Pneumologie ◽  
2011 ◽  
Vol 65 (12) ◽  
Author(s):  
F Behler ◽  
K Steinwede ◽  
R Maus ◽  
J Bohling ◽  
UA Maus
Keyword(s):  
Host Defense ◽  
Mycobacterial Infections

scholarly journals Importance of the loop connecting A and B helices of human interferon-gamma in recognition by interferon-gamma receptor.

1994 ◽  
Vol 269 (23) ◽  
pp. 16159-16162 ◽  
Author(s):  
D. Lundell ◽  
C.A. Lunn ◽  
M.M. Senior ◽  
P.J. Zavodny ◽  
S.K. Narula
Keyword(s):  
Interferon Gamma ◽  
Human Interferon ◽  
Gamma Receptor
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