A comparative study of cilostazol and pentoxifylline in intermittent claudication in peripheral arterial disease

Author(s):  
Chandrashekhar Mahakalkar ◽  
Kshitij Gupta ◽  
Meghali Kaple ◽  
Swati Deshpande ◽  
Prateek Ladhha ◽  
...  
Author(s):  
Susan Matthews ◽  
Martin Fox ◽  
Sarah Coy ◽  
Jane Whittaker ◽  
Gail Brough ◽  
...  

Background/Aims Peripheral arterial disease is common among those aged 60 years or above and can cause debilitating intermittent claudication. This impacts quality of life and is a marker for increased morbidity and mortality, mainly from cardiovascular disease. Access to recommended exercise programmes for people with symptomatic peripheral arterial disease is poor in most areas of the UK. This study aimed to evaluate the benefits of expanding an established cardiac rehabilitation service to accommodate supervised exercise for people with peripheral arterial disease Methods The study evaluated 11 participants peripheral arterial disease and intermittent claudication who were referred by the Manchester leg circulation service. Participants underwent the programme involving eight weekly 1.5 hour sessions of supervised exercise and cardiovascular education with support, reassurance and motivation. The participants' blood pressure, walking impairment, quality of life, anxiety and depression were monitored and reviewed. Results Overall, the participants' walking distance, intermittent claudication, quality of life and blood pressure had improved. The participants' overall satisfaction with the programme was excellent. The programme also demonstrated clinical and cost-effectiveness. Conclusions A structured, supervised exercise programme can have considerable benefits for people with peripheral arterial disease, improving their symptoms and quality of life. It may also help to reduce the morbidity and mortality risks associated with inactivity in this patient group.


2021 ◽  
Vol 322 ◽  
pp. 227-232
Author(s):  
Željko Reiner ◽  
Johan De Sutter ◽  
Lars Ryden ◽  
Erkin Mirrakhimov ◽  
Nana Pogosova ◽  
...  

JAMA ◽  
2009 ◽  
Vol 301 (2) ◽  
pp. 165 ◽  
Author(s):  
Mary M. McDermott ◽  
Philip Ades ◽  
Jack M. Guralnik ◽  
Alan Dyer ◽  
Luigi Ferrucci ◽  
...  

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