scholarly journals Subthreshold continuous wave autofluorescence-controlled laser treatment of chronic central serous chorioretinopathy

2018 ◽  
Vol 13 (3) ◽  
pp. 236 ◽  
Author(s):  
MohammadReza Khalili ◽  
Hossein Ashraf ◽  
Mansooreh Jamshidian ◽  
Mousa Zare ◽  
Anis Shamsi
2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Dominik Odrobina ◽  
Iwona Laudańska-Olszewska ◽  
Piotr Gozdek ◽  
Mariusz Maroszyński ◽  
Michael Amon

Purpose. To analyze microstructural changes in the external limiting membrane (ELM) and photoreceptor layer before and after early and late conventional laser treatment in central serous chorioretinopathy (CSC) in 12 months follow-up study.Methods. A retrospective observational study included Group A: 19 patients (19 eyes) with symptomatic acute CSC and Group B: 16 patients (16 eyes) with symptomatic chronic CSC. Retinal microstructural changes were analyzed with SD-OCT paying a particular role in examining the photoreceptor layer and ELM.Results. The length of the photoreceptors, prior to treatment, was approximately 84 μm in Group A and 82,5 μm in Group B. Twelve months after laser treatment, photoreceptor length was approximately 49 μm in Group A and 43 μm (range 20–55 μm) in Group B. No patients in Group A had noticeable photoreceptor defects nor ELM defects, but in 15 eyes in Group B photoreceptor and ELM defects were detected ().Conclusions. When analyzing the photoreceptor layer and ELM during active CSC, it is not possible to evaluate any irreversible changes which have already occurred in this layer. Damage to the photoreceptor layer and ELM in patients with chronic CSC was only found after laser treatment and the absorption of subretinal fluid.


2020 ◽  
Vol 2020 ◽  
pp. 1-5 ◽  
Author(s):  
Katarzyna Piasecka ◽  
Piotr Gozdek ◽  
Mariusz Maroszyński ◽  
Dominik Odrobina

The aim of this study was to analyze the efficacy of micropulse laser treatment (MLT) compared with the continuous-wave laser (CL) in treating eyes with chronic central serous chorioretinopathy (CSC) in a 12-month follow-up study. Methods: A retrospective observational study included 51 eyes with chronic CSC; 35 eyes were treated with MLT (Group A), and 16 eyes were treated with CL (Group B). We analyzed the best corrected visual acuity (BCVA) and retinal microstructural changes in spectral optical coherence tomography before the treatment, one and twelve months after the laser procedure. Results: The final mean BCVA was 0.89 ± 0.13 in Group A and 0.71 ± 0.17 in Group B. Photoreceptor length decreased significantly in both groups and amounted 61.2 μm in Group A and 42.9 μm in Group B one year after the treatment. Complete absorption of subretinal fluid twelve months after the laser procedure was noted in 74.3% eyes in Group A and in 87.5% eyes in group B. Hyper-reflective subretinal deposits were observed in 10/35 eyes in Group A but in 15/16 eyes in Group B on the final follow-up visit. Conclusion. MLT-treated patients showed better functional and microstructural results than patients treated with CL.


Author(s):  
Benedikt Schworm ◽  
Jakob Siedlecki ◽  
Leonie F. Keidel ◽  
Tina R. Herold ◽  
Nikolaus Luft ◽  
...  

Abstract Purpose There is an ongoing controversial debate about the effectiveness of laser treatments in chronic central serous chorioretinopathy (cCSC). We performed a prospective non-randomized interventional study to learn about the effects of a subthreshold laser treatment (Topcon Endpoint Management™, Topcon Healthcare Inc., Tokyo, Japan) in patients with cCSC. Methods Patients with cCSC and a minimum symptom duration of 4 months were included and treated with a standardized laser pattern covering the macular area. Retreatment was performed every 3 months if persistent subretinal fluid was observed. The primary endpoint was resolution of subretinal fluid at 6 months. Further outcome parameters included best corrected visual acuity, microperimetry, central macular and subfoveal choroidal thickness. Results A total of 42 eyes of 39 patients were included. Mean patient age was 48 ± 10.6 years (range 25–67). Mean symptomatic time before inclusion into the study was 134 ± 133.4 weeks (16–518). Before inclusion, 78.6% of the patients had failed to resolve subretinal fluid under mineralocorticoid receptor antagonists and 14.3% had a recurrence after half-dose photodynamic therapy. Complete resolution of subretinal fluid was observed in 42.9% at 6 months and in 53.8% at 12 months after baseline. Central retinal thickness decreased from 398 ± 135 µm to 291 ± 68 µm (p < 0.001), subfoveal choroidal thickness changed slightly (430 ± 116 µm to 419 ± 113 µm, p = 0.026), microperimetry-derived macular function improved by 19.1 ± 4.7 dB to 21.3 ± 4.8 dB (p = 0.008) and mean BCVA improved by 4.9 ± 8.6 ETDRS letters (p < 0.001). Conclusion The results show that the investigated laser treatment is effective in reducing subretinal fluid and leads to an improvement of functional parameters.


2019 ◽  
Vol 15 (4) ◽  
pp. 394-404
Author(s):  
P. L. Volodin ◽  
A. V. Doga ◽  
E. V. Ivanova ◽  
V. A. Pismenskaya ◽  
Iu. I. Kukharskaya ◽  
...  

The Purpose— to develop the technology and to evaluate the clinical results of personalized laser treatment of patients with chronic central serous chorioretinopathy (CSC) in a micropulse mode with individual selection of energy parameters on the navigation system Navilas 577s.Patients and Methods. 19 patients (22 eyes) with CSC after micropulse laser treatment were analyzed. The initial best corrected visual acuity (BCVA) was 0.4 to 1.0. According to OCT, the height of the  detachment of the neurosensory retina varied from 83 to 259 microns. Retinal sensitivity of the central zone was from 20.2 to 29.7 dB. Before laser treatment were individually selected the optimal energy parameters for each patient. The treatment was performed on a Navilas 577s laser system. The follow-up were 1 and 3 months.Results. 1 month after treatment the positive dynamics of functional and anatomical results in all patients was observed. Mean BCVA increased in the group to 0.81 ± 0.04. The central retinal sensitivity raised on average in the group up to 25.7 ± 0.6 dB. After 3 months, mean BCVA was 0.96 ± 0.02. Mean central retinal sensitivity increased to 26.4 ± 0.57 dB. The study revealed a high correlation between visual acuity and the central retinal thickness (0.72) and medium correlation between foveal retinal sensitivity and central retinal thickness in fovea (0.60), respectively. The correlation among visual acuity, retinal sensitivity and the symptom’s duration of the disease is negative medium (-0.63) and significant (-0.72), respectively.Conclusions. The developed personalized technology of laser treatment of chronic central serous chorioretinopathy with a micropulse mode with an individual selection of energy parameters on the Navilas 577s navigation system showed high clinical efficiency and safety. It has been established that in the course of the longstanding duration of the disease irreversible changes in the chorioretinal complex structure occured, thinning of the foveal photoreceptors layer leading to a decrease in the central retinal sensitivity and visual acuity, which substantiate the necessity for early and maximally functional-saving treatment.


2019 ◽  
Vol 100 (4) ◽  
pp. 601-605
Author(s):  
A N Samoylov ◽  
A N Korobitsin

Aim. Develop a methodology and evaluate the clinical results of laser treatment of patients with chronic central serous chorioretinopathy in the presence of a leakage point in the foveola zone. Methods. The results of patients (32 eyes) with central serous chorioretinopathy after laser exposure in the avascular area were analyzed. The best-corrected visual acuity in these patients before treatment was 0.7 to 1.0 (average 0.78±0.15) with a height of neuroepithelial detachment of 162 to 328 μm according to optical coherence tomography. No signs of choroidal neovascularization was detected in angio mode on optical coherence tomography. The treatment was performed with an Ellex Integre Pro Scan 561 nm. The follow-up examination was performed in 1 and 6 months. Results. In 1 month, positive dynamics of both functional and anatomical parameters was noted in all eyes. According to the optical coherence tomography, a complete attachment of the neuroepithelium in the central zone of the retina occurred, detachment of the neuroepithelium was absent. Best-corrected visual acuity in 1 month after treatment increased to 0.89±0.08, in 6 months to 0.92±0.04. The study revealed a correlation between visual acuity and the central thickness of the retina in the fovea, there were no complaints about the appearance of scotomas after laser treatment in the foveola zone. Conclusion. The developed techniqe of laser exposure on the foveola zone in case of chronic central serous chorioretinopathy with a 561 nm laser demonstrated high clinical efficacy and safety and can be recommended to all patients with central serous chorioretinopathy.


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