A REPEAT MATING DESIGN IN A SELECTION EXPERIMENT

1980 ◽  
Vol 60 (4) ◽  
pp. 833-841
Author(s):  
R. J. PARKER ◽  
T. K. CHEUNG ◽  
K. M. WITTENBERG ◽  
C. G. HICKMAN
Keyword(s):  
Selection Response ◽  
Mass Selection ◽  
Response To Selection ◽  
Genetic Response ◽  
Mating Design ◽  
Litter Weight ◽  
The Third ◽  
Mating Population ◽  
Selection For ◽  
Selection Intensities

The separation of genetic and environmental trends in a repeat mating design and the effectiveness of such a design in producing genetic response to selection were observed during eight cycles of directional selection for high 12-day litter weight in mice. A random-bred control was used to monitor the repeat mating design in estimating environmental trend. Two mass selection populations (M1 and M2) under different selection intensities were used to assess the success of the repeat mating design in achieving selection response. From the third to the eighth cycle, the estimated genetic gain in 12-day litter weight for the repeat mating population was 0.89 ± 0.25 g per cycle. The selection response from the repeat design was lower than from one mass selection population (M2) but higher than from the other (M1). The environmental trend estimate of −0.79 ± 0.78 g per cycle was in fair agreement with the estimate of −0.88 ± 0.55 g per cycle from the random bred control.

scholarly journals RESPONSE TO SELECTION FOR BODY WEIGHT IN THE THIRD GENERATION OF MASS SELECTION OF THE AFRICAN CATFISH (Clarias gariepinus) AT RESEARCH INSTITUTE FOR FISH BREEDING SUKAMANDI

2016 ◽  
Vol 11 (1) ◽  
pp. 15
Author(s):  
Bambang Iswanto ◽  
Imron Imron ◽  
Huria Marnis ◽  
Rommy Suprapto
Keyword(s):  
Body Weight ◽  
Second Generation ◽  
Clarias Gariepinus ◽  
Mass Selection ◽  
African Catfish ◽  
Larval Rearing ◽  
Third Generation ◽  
Response To Selection ◽  
The Third ◽  
Selection For

Genetic improvement of the African catfish (Clarias gariepinus) in Indonesia for increasing growth performance has been conducted by Research Institute for Fish Breeding at Sukamandi through mass selection. Collection and characterizations of the founder populations, building the synthetic base population, first generation and second generation through mass selection were conducted during 2010-2013. Later, in 2014 it was followed by building the third generation. The present study aimed to find out the genetic gain in the third generation in term of response to selection for body weight. Fifty-two pairs of the selected (fast growing) individuals from the second generation were mated to produce the third generation. As a comparison, five pairs of average-sized individuals were mated to produce the control population, as a second generation representative. Larval rearing, nursery and grow-out phases were respectively held for 25 days in the aquaria, 30 days in the concrete ponds and 60 days in the concrete ponds. At the end of each phase, individual samplings of body weight were undertaken. The results showed that mean body weight of the third generation was higher than that of control population at the end of larval rearing phase (0.21 ± 0.26 g versus 0.20 ± 0.15 g), nursery phase (6.12 ± 2.93 g versus 5.80 ± 3.50 g) and grow-out phase (198.67 ± 82.82 g versus 165.22 ± 71.09 g). Those results revealed that response to selection for body weight of the third generation was positive, i.e. about 20.24% (33.45 g).

scholarly journals EFFECTS OF POPULATION SIZE AND SELECTION INTENSITY ON SHORT-TERM RESPONSE TO SELECTION FOR POSTWEANING GAIN IN MICE

Genetics ◽  
1973 ◽  
Vol 73 (3) ◽  
pp. 513-530
Author(s):  
J P Hanrahan ◽  
E J Eisen ◽  
J E Legates
Keyword(s):  
Population Size ◽  
Selection Response ◽  
Selection Intensity ◽  
Realized Heritability ◽  
Family Selection ◽  
Effective Population ◽  
Population Sizes ◽  
Selection For ◽  
Selection Intensities ◽  
Term Response

ABSTRACT The effects of population size and selection intensity on the mean response was examined after 14 generations of within full-sib family selection for postweaning gain in mice. Population sizes of 1, 2, 4, 8 and 16 pair matings were each evaluated at selection intensities of 100% (control), 50% and 25% in a replicated experiment. Selection response per generation increased as selection intensity increased. Selection response and realized heritability tended to increase with increasing population size. Replicate variability in realized heritability was large at population sizes of 1, 2 and 4 pairs. Genetic drift was implicated as the primary factor causing the reduced response and lowered repeatability at the smaller population sizes. Lines with intended effective population sizes of 62 yielded larger selection responses per unit selection differential than lines with effective population sizes of 30 or less.

scholarly journals A SIMULATION STUDY OF TRUNCATION SELECTION FOR A QUANTITATIVE TRAIT OPPOSED BY NATURAL SELECTION

Genetics ◽  
1980 ◽  
Vol 94 (4) ◽  
pp. 989-1000
Author(s):  
Francis Minvielle
Keyword(s):  
Natural Selection ◽  
Artificial Selection ◽  
Random Mating ◽  
Selection Response ◽  
Quantitative Character ◽  
Mass Selection ◽  
Frequency Selection ◽  
Selection Experiments ◽  
Selection For ◽  
Selective Process

ABSTRACT A quantitative character controlled at one locus with two alleles was submitted to artificial (mass) selection and to three modes of opposing natural selection (directional selection, overdominance and underdominance) in a large random-mating population. The selection response and the limits of the selective process were studied by deterministic simulation. The lifetime of the process was generally between 20 and 100 generations and did not appear to depend on the mode of natural selection. However, depending on the values of the parameters (initial gene frequency, selection intensity, ratio of the effect of the gene to the environmental standard deviation, fitness values) the following outcomes of selection were observed: fixation of the allele favored by artificial selection, stable nontrivial equilibrium, unstable equilibrium and loss of the allele favored by artificial selection. Finally, the results of the simulation were compared to the results of selection experiments.

RESPONSE TO SELECTION FOR BODY WEIGHT OR FEED EFFICIENCY IN MICE TESTED ON CORN, RYE AND WHEAT DIETS

1986 ◽  
Vol 66 (2) ◽  
pp. 389-397
Author(s):  
R. I. McKAY ◽  
R. J. PARKER ◽  
W. GUENTER
Keyword(s):  
Body Weight ◽  
Feed Efficiency ◽  
Mass Selection ◽  
Response To Selection ◽  
Initial Weight ◽  
Commercial Diet ◽  
Final Weight ◽  
Dc Line ◽  
Selection For ◽  
Seven Generations

Mass selection for adjusted feed efficiency (AFE, g gain/g feed) and adjusted body weight (ABW, g) of male mice was practiced for seven generations on each of three diets: corn, rye and wheat. The three experimental diets, fed between 21 and 35 d, were isocaloric (approximately 16.5 MJ GE kg−1) and isonitrogenous (CP approximately 13%). A common commerical diet (PC) was fed at all other times. With each diet two control lines, randomly mated, were tested on either the experimental diets (DC) or a commercial diet (PC). Selection was based upon linear adjustment to a common initial weight (10 g) for either final weight (ABW) or feed efficiency (AFE) measured between 21 and 35 d of age. Response was determined as a deviation from the appropriate DC line. All animals were placed in specially designed individual cages during the test period. Half-sib estimates of heritability in the PC line were 0.13(± 0.11) for ABW and 0.19(± 0.10) for AFE. Half-sib estimates pooled across lines and diets were 0.16(± 0.07) for ABW and 0.28(± 0.07) for AFE. Realized heritabilities for ABW were 0.24(± 0.06), 0.06(± 0.07) and 0.14(± 0.06) for the corn, rye and wheat diets, respectively. Response to selection for AFE was poor with the highest heritability obtained on the wheat diet (h2 = 0.13 ± 0.02). Key words: Selection, mice, body weight, feed efficiency, diets

INHERITANCE OF WEIGHTS OF LAMBS REARED ARTIFICIALLY OR WITH THEIR DAMS

1983 ◽  
Vol 63 (2) ◽  
pp. 263-268 ◽  
Author(s):  
J. N. B. SHRESTHA ◽  
H. F. PETERS ◽  
D. P. HEANEY
Keyword(s):  
Genetic Correlation ◽  
Direct Selection ◽  
Milk Replacer ◽  
Response To Selection ◽  
Genetic Response ◽  
Artificial Rearing ◽  
Solid Diet ◽  
Selection For ◽  
Heritability Estimates ◽  
Age Estimates

This study involved 250 lambs reared artificially with milk replacer and solid diet from 2 to 70 days and 316 lambs creep-fed solid diet and reared with their dams from birth to 70 days. Thereafter, all lambs were retained on solid diet to 140 days of age. Heritability estimates for weights of lambs reared artificially tended to be larger than the corresponding estimates for lambs reared with their dams (P > 0.05). Phenotypic variances of lambs reared with their dams were larger at birth and at 35 days, whereas lambs reared artificially had larger phenotypic variances at 70 and 140 days of age. Estimates of genetic correlation between half-sib family means of lambs reared artificially with corresponding half-sibs reared with their dams ranged from 0.15 to 0.91, suggesting the absence of sire × rearing system interaction. We conclude that greater genetic response to selection for lamb weights at various ages could be achieved from direct selection among lambs reared artificially compared to those reared with their dams. However, in the absence of artificial rearing, prospective breeding stock reared with their dams should be tested for postweaning performance to permit full expression of transmitted sire differences. Key words: Sheep, lamb rearing, heritability estimates, genetic correlation

scholarly journals Response to selection for increased pupa weight in Tribolium castaneum as related to population structure

1977 ◽  
Vol 30 (3) ◽  
pp. 237-246 ◽  
Author(s):  
Alan J. Katz ◽  
Franklin D. Enfield
Keyword(s):  
Random Mating ◽  
Selection Response ◽  
Response To Selection ◽  
Short Term ◽  
Selection Systems ◽  
Line Selection ◽  
Selection For ◽  
Seven Generations ◽  
Generation Period ◽  
Term Response

SUMMARYThe effectiveness of selection for increased pupa weight in Tribolium was compared for three different selection systems. In all three systems the same number of breeding individuals was used each generation. Population L was a large random mating population with 24 males and 48 females selected each generation. The C4 and C8 populations were each divided into 6 subpopulations (lines) consisting of 4 males and 8 fem ales. Each of the three populations was replicated. In C4, selection for pupa weight was within lines for three generations, followed by a generation of among-line selection when the best two out of six lines were selected. These lines were then crossed to produce 6 new subpopulations, and the cycle was repeated. The C8 population was handled in exactly the same manner except that seven generations of selection within lines were practised before each generation of among-line selection. Selection response for the 42-generation period was significantly greater in the L population than in either subdivided population. No consistent differences among the selection systems were apparent when evaluating short-term response for the first 12 generations of the experiment. The results were interpreted as indicating that the influence of multiple-peak epistasis was not of major importance for this trait in determining ultimate response to selection when starting from a base population of previously unselected lines and utilizing a within- and among-line selection regime.

scholarly journals SELECTION FOR HIGH ADULT BODY WEIGHT IN DROSOPHILA POPULATIONS WITH DIFFERENT STRUCTURES

Genetics ◽  
1975 ◽  
Vol 81 (1) ◽  
pp. 163-175
Author(s):  
A J Katz ◽  
S S Y Young
Keyword(s):  
Body Weight ◽  
Random Mating ◽  
Large Mass ◽  
Mass Selection ◽  
Adult Body ◽  
Large Populations ◽  
Subdivided Populations ◽  
Adult Body Weight ◽  
Selection For ◽  
Selection Intensities

ABSTRACT Selection for high adult body weight in Drosophila melanogaster was practiced for 18 generations in three selection lines. These lines were genetically similar and of equal size but different in population structure. One line represented a large mass-selected, random-mating population, while the other two lines simulated large populations that had been subdivided into partial isolates or demes. Mass selection and random mating occurred within each deme. These two subdivided lines were different only in the rate of effective migration among the demes (5% and 10%). Selection intensities of approximately 20% were applied to these populations. A fourth line served as a random mating control. Heritability of adult body weight in the base population was estimated to be 0.58± 0.22. The results indicate that significantly greater responses were achieved in the subdivided lines than in the large mass-selected line, in spite of the fact that larger selection differentials were applied to the latter. No significant differences in response were observed between the two subdivided lines. Wright (1930, 1931) postulated that selection would be most efficient in subdivided populations with limited interdeme migration. The present findings appear to support this theory.

scholarly journals Two-way within-family and mass selection for 8-week body weight in different mouse populations

1984 ◽  
Vol 43 (2) ◽  
pp. 191-200 ◽  
Author(s):  
Ines von Butler ◽  
Henning Willeke ◽  
Franz Pirchner
Keyword(s):  
Body Weight ◽  
Inbred Strains ◽  
Selection Response ◽  
Mass Selection ◽  
Individual Selection ◽  
Family Selection ◽  
Body Weights ◽  
Selection For ◽  
Size At Birth ◽  
Better Than

SUMMARYTwo mouse populations, randombred albino mice and a cross of four inbred strains, were divergently selected for high (H8) and low (L8) 8-week body weight over 18 generations using within-family and individual selection. The crossbreds showed asymmetry of selection response and realized heritabilities (H8 0·29 ± 0·01; L8 0·17 ± 0·01). In the randombred population realized heritabilities were symmetrical (H8 0·23 ± 0·01; L8 0·22 ± 0·02). Over the first nine generations individual selection was nearly 40 per cent better than within-family selection, as was expected from the full sib correlation in both populations. As selection progressed, within-family selection reached 82% and 61% of the responses obtained with individual selection in the crossbreds and randombred respectively. Correlated responses for 3-week (weaning) and 5-week body weights agreed with observations made on direct responses, but selection for L8 did not reduce weaning weight. Selection for L8 decreased and selection for H8 increased first litter size at birth. However, mass-selected L8-pairs had a higher life-reproduction and life-span than H8-pairs.

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