EFFECT OF pH, CALCIUM CONCENTRATION AND TEMPERATURE ON THE HYDROLYSIS OF DICALCIUM PHOSPHATE DIHYDRATE

1989 ◽  
Vol 69 (3) ◽  
pp. 689-693 ◽  
Author(s):  
G. W. MORDEN ◽  
G. J. RACZ
Keyword(s):  
Key Words ◽  
Calcium Concentration ◽  
Dicalcium Phosphate ◽  
Dicalcium Phosphate Dihydrate ◽  
Effect Of Ph ◽  
Ph Values ◽  
Phosphate Dihydrate ◽  
Rate Of Hydrolysis ◽  
Hydrolysis Of

The rate of hydrolysis of DCPD to OCP in solutions of different pH values, calcium concentrations and temperatures was studied. Rates of hydrolysis were very slow at pH 6.0, relatively rapid and similar at pH 7.0 and 8.0, much slower at 10 °C than at 20 or 30 °C, and only slightly increased by increasing calcium concentration. Key words: Dicalcium phosphate dihydrate, hydrolysis, pH, temperature, calcium concentration

Structural changes during the hydrolysis of dicalcium phosphate dihydrate to octacalcium phosphate and hydroxyapatite

2015 ◽  
Vol 51 (4) ◽  
pp. 355-361 ◽  
Author(s):  
V. F. Shamrai ◽  
A. E. Karpikhin ◽  
A. Yu. Fedotov ◽  
V. P. Sirotinkin ◽  
S. M. Barinov ◽  
...  
Keyword(s):  
Structural Changes ◽  
Octacalcium Phosphate ◽  
Dicalcium Phosphate ◽  
Dicalcium Phosphate Dihydrate ◽  
Phosphate Dihydrate ◽  
Hydrolysis Of

Hydrolysis of dicalcium phosphate dihydrate in a sodium acetate solution

2012 ◽  
Vol 447 (2) ◽  
pp. 303-305 ◽  
Author(s):  
I. V. Fadeeva ◽  
S. M. Barinov ◽  
D. Ferro ◽  
V. S. Komlev ◽  
L. I. Shvorneva
Keyword(s):  
Sodium Acetate ◽  
Dicalcium Phosphate ◽  
Sodium Acetate Solution ◽  
Acetate Solution ◽  
Dicalcium Phosphate Dihydrate ◽  
Phosphate Dihydrate ◽  
Hydrolysis Of

Decoupling the Eeffects of Esurface Chemistry and Humidity on Solid-State Hydrolysis of Aspirin in the Presence of Dicalcium Phosphate Dihydrate

2012 ◽  
Vol 101 (4) ◽  
pp. 1496-1507 ◽  
Author(s):  
Andrew M. Cassidy ◽  
Catherine E. Gardner ◽  
Tony Auffret ◽  
Barry Aldous ◽  
William Jones
Keyword(s):  
Solid State ◽  
Dicalcium Phosphate ◽  
Dicalcium Phosphate Dihydrate ◽  
Phosphate Dihydrate ◽  
Hydrolysis Of

scholarly journals Phosphatase synthesis in Klebsiella (Aerobacter) aerogenes growing in continuous culture

1972 ◽  
Vol 127 (1) ◽  
pp. 87-96 ◽  
Author(s):  
P. G. Bolton ◽  
A. C. R. Dean
Keyword(s):  
Alkaline Phosphatase ◽  
Acid Phosphatase ◽  
Continuous Culture ◽  
Activity Profile ◽  
Glucose Effect ◽  
Ph Values ◽  
Nitrophenyl Phosphate ◽  
Wide Range ◽  
Rate Of Hydrolysis ◽  
Hydrolysis Of

1. Phosphatase synthesis was studied in Klebsiella aerogenes grown in a wide range of continuous-culture systems. 2. Maximum acid phosphatase synthesis was associated with nutrient-limited, particularly carbohydrate-limited, growth at a relatively low rate, glucose-limited cells exhibiting the highest activity. Compared with glucose as the carbon-limiting growth material, other sugars not only altered the activity but also changed the pH–activity profile of the enzyme(s). 3. The affinity of the acid phosphatase in glucose-limited cells towards p-nitrophenyl phosphate (Km 0.25–0.43mm) was similar to that of staphylococcal acid phosphatase but was ten times greater than that of the Escherichia coli enzyme. 4. PO43−-limitation derepressed alkaline phosphatase synthesis but the amounts of activity were largely independent of the carbon source used for growth. 5. The enzymes were further differentiated by the effect of adding inhibitors (F−, PO43−) and sugars to the reaction mixture during the assays. In particular, it was shown that adding glucose, but not other sugars, stimulated the rate of hydrolysis of p-nitrophenyl phosphate by the acid phosphatase in carbohydrate-limited cells at low pH values (<4.6) but inhibited it at high pH values (>4.6). Alkaline phosphatase activity was unaffected. 6. The function of phosphatases in general is discussed and possible mechanisms for the glucose effect are outlined.

Behavior of Osteoclast Cells Response on Dicalcium Phosphate Dihydrate Layer-Coated β-Tricalcium Phosphate Granular

2020 ◽  
Vol 1010 ◽  
pp. 549-554
Author(s):  
Khairul Anuar Shariff ◽  
Mohamad Hafizi Abu Bakar ◽  
Arief Cahyanto
Keyword(s):  
Bone Formation ◽  
Dicalcium Phosphate ◽  
Phosphate Solution ◽  
Dicalcium Phosphate Dihydrate ◽  
New Bone Formation ◽  
Osteoblast Cells ◽  
Calvarial Bone ◽  
Phosphate Dihydrate ◽  
Trap Staining ◽  
Block Section

The aim of this study is to investigate the behavior of osteoclast cells response on dicalcium phosphate dihydrate (DCPD) layer-coated β-TCP granules. β-TCP granules with 300-600 μm were exposed to acidic calcium phosphate solution for 30 mins in order to get 10 mol% DCPD layer-coated β-TCP granular. DCPD free-coated β-TCP granular had used as control specimen. Both specimens were implant in 9 mm of rat calvarial bone defect for 4 weeks. After 4 weeks, the block section of rat calvarial containing specimen were removed for Tatrate-Resistance Acid Phosphatase (TRAP) analysis. Results of TRAP staining reveal that the number of osteoclast cells attached on 10 mol% layer-coated β-TCP granular is higher than DCPD free-coated β-TCP granular. Since remodeling of new bone formation involved simultaneous osteoclast and osteoblast cells response, therefore, the results obtained in this study indicated that the presence of DCPD layer-coated on β-TCP granular helps to improve osteoclast cells response that contribute in stimulating new bone formation.

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