The role of single- and multi-walled carbon nanotube in breast cancer treatment

2020 ◽  
Vol 11 (10) ◽  
pp. 653-672 ◽  
Author(s):  
Babak Faraji Dizaji ◽  
Amirnezam Farboudi ◽  
Alireza Rahbar ◽  
Mohammadreza Hasani Azarbaijan ◽  
Mohammad Reza Asgary
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Carbon Nanomaterials ◽  
Breast Cancer Diagnosis ◽  
Breast Cancer Treatment ◽  
Wide Range ◽  
Multi Walled Carbon Nanotubes ◽  
Swcnts And Mwcnts ◽  
Walled Carbon Nanotubes

Numerous studies have been conducted to design new strategies for breast cancer treatment. Past studies have shown a wide range of carbon-nanomaterials properties, such as single- and multi-walled carbon nanotubes (SWCNTs and MWCNTs) in breast cancer diagnosis and treatment. In this regard, the current study aims to review the role of both SWCNTs and MWCNTs in breast cancer treatment and diagnosis. For reaching this goal, we reviewed the literature by using various searching engines such as Scopus, PubMed, Google Scholar, Web of Science and MEDLINE. This comprehensive review showed that CNTs could dramatically improve breast cancer treatment and could be used as a novel modality to increase diagnostic accuracy; however, no clinical studies have been conducted based on CNTs. In addition, the literature review demonstrates a lack of enough studies to evaluate the side effects of using CNTs.

Immunotherapy: New insights in breast cancer treatment

2021 ◽  
pp. 1-10
Author(s):  
Bader Alshehri
Keyword(s):  
Breast Cancer ◽  
Immune Response ◽  
Immune System ◽  
Cancer Treatment ◽  
Immune Evasion ◽  
Breast Tumor ◽  
Parp Inhibitor ◽  
Breast Cancer Treatment ◽  
New Treatment

Breast cancer being the most malignant and lethal disease persistent among women globally. Immunotherapy as a new treatment modality has emerged in understanding the loopholes in the treatment of breast cancer which is mainly attributed to the potential of tumor cells to evade and survive the immune response by developing various strategies. Therefore, improved understanding of the immune evasion by cancer cells and the monoclonal antibodies against PD- and PD-L1 can help us in the diagnosis of this malignancy. Here in this article, I have highlighted that in addition to focusing on other strategies for breast cancer treatment, the involvement of immune system in breast cancer is vital for the understanding of this malignancy. Further, the complete involvement of immune system in the relapse or recurrence of the breast tumor and have also highlighted the role of vaccines, PD-1 and CTLA-4 with the recent advances in the field. Moreover, in addition to the application of immunotherapy as a sole therapy, combinations of immunotherapy with various strategies like targeting it with MEK inhibitors, Vaccines, chemotherapy and PARP inhibitor has shown to have significant benefits is also discussed in this article.

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