scholarly journals kin-19/casein kinase Iαhas dual functions in regulating asymmetric division and terminal differentiation inC. elegansepidermal stem cells

Cell Cycle ◽  
2010 ◽  
Vol 9 (23) ◽  
pp. 4748-4765 ◽  
Author(s):  
Diya Banerjee ◽  
Xin Chen ◽  
Shin Yi Lin ◽  
Frank J. Slack
Keyword(s):  
Stem Cells ◽  
Terminal Differentiation ◽  
Asymmetric Division ◽  
Casein Kinase ◽  
Dual Functions

Gene mutation and aneuploidy might cooperate to carcinogenesis by dysregulation of asymmetric division of adult stem cells

2006 ◽  
Vol 67 (4) ◽  
pp. 995-996
Author(s):  
Feng Zhang ◽  
Daqing Zhao ◽  
Guangsheng Chen ◽  
Qing Li
Keyword(s):  
Stem Cells ◽  
Gene Mutation ◽  
Adult Stem Cells ◽  
Asymmetric Division

Neuroblasts: a model for the asymmetric division of stem cells

1997 ◽  
Vol 13 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Haifan Lin ◽  
Trista Schagat
Keyword(s):  
Stem Cells ◽  
Asymmetric Division

scholarly journals Mesenchymal stem cells suppress B-cell terminal differentiation

2009 ◽  
Vol 37 (5) ◽  
pp. 604-615 ◽  
Author(s):  
Sadaki Asari ◽  
Shin Itakura ◽  
Kevin Ferreri ◽  
Chih-Pin Liu ◽  
Yoshikazu Kuroda ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
B Cell ◽  
Terminal Differentiation

scholarly journals Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1

2016 ◽  
Vol 23 (4) ◽  
pp. 494-507 ◽  
Author(s):  
Andrei Ursu ◽  
Damir J. Illich ◽  
Yasushi Takemoto ◽  
Arthur T. Porfetye ◽  
Miao Zhang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Casein Kinase ◽  
Casein Kinase 1 ◽  
Epiblast Stem Cells

scholarly journals Terminal differentiation of ectodermal epithelial stem cells of Hydra can occur in G2 without requiring mitosis or S phase.

1990 ◽  
Vol 110 (4) ◽  
pp. 939-945 ◽  
Author(s):  
S Dübel ◽  
H C Schaller
Keyword(s):  
Cell Cycle ◽  
Stem Cells ◽  
Epithelial Cells ◽  
Terminal Differentiation ◽  
S Phase ◽  
Epithelial Stem Cells ◽  
Proliferating Cells ◽  
Specific Differentiation ◽  
G2 Phase

Using bromodeoxyuridine incorporation to label cells in S phase we found that ectodermal epithelial cells of Hydra can start and complete their terminal differentiation in the G2 phase of the cell cycle. Most of the cells traversed their last S phase before the signal for differentiation, namely excision of head or foot, was given. The S phase inhibitor aphidicolin accordingly did not inhibit head or foot specific differentiation. The results show that differentiation to either head- or foot-specific ectodermal epithelial cells can start and is completed within the same G2 phase. This is therefore the first description of a complete differentiation from a population of proliferating cells to terminally differentiated, cell cycle-arrested cells without the necessity of passing through an S phase or mitosis.

scholarly journals Inflammation-mediated age-dependent effects of casein kinase 2-interacting protein-1 on osteogenesis in mesenchymal stem cells

2020 ◽  
Vol 133 (16) ◽  
pp. 1935-1942
Author(s):  
Xiao-Guang Tian ◽  
Fei-Fei Gong ◽  
Xi Li ◽  
Fan-Hao Meng ◽  
Zheng Zhou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Casein Kinase ◽  
Casein Kinase 2 ◽  
Interacting Protein ◽  
Age Dependent

Abstract 11: Asymmetric division via nonrandom chromosomal cosegregation potentially defines a novel class of universal cancer stem cells

2010 ◽  
Author(s):  
Hong-Wu Xin ◽  
Danielle M. Hari ◽  
Kshama R. Jaiswal ◽  
Bo-Kyu Kim ◽  
Satyajit Ray ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Asymmetric Division

scholarly journals Purified interleukin-3 and erythropoietin support the terminal differentiation of hemopoietic progenitors in serum-free culture

Blood ◽  
1986 ◽  
Vol 67 (4) ◽  
pp. 1002-1006 ◽  
Author(s):  
J Suda ◽  
T Suda ◽  
K Kubota ◽  
JN Ihle ◽  
M Saito ◽  
...  
Keyword(s):  
Stem Cells ◽  
Progenitor Cells ◽  
Terminal Differentiation ◽  
Cell Transfer ◽  
Erythroid Cells ◽  
Spleen Cells ◽  
Serum Free ◽  
Interleukin 3 ◽  
Specific Factors ◽  
Late Stages

Abstract We studied the effect of purified interleukin-3 (IL-3) and erythropoietin on colony formation by hemopoietic progenitors in serum- free cultures of spleen cells from 5-fluorouracil (5-FU)-treated mice. In the presence of IL-3 alone, most of the multilineage (three or more lineages) colonies did not contain erythroid cells. However, in the presence of IL-3 and erythropoietin, most of the multilineage colonies contained various numbers of erythroid cells. Replating experiments suggest that IL-3 maintains the growth of the progenitor cells, which could differentiate into erythroid cells. Erythropoietin facilitated the terminal differentiation and amplification of erythroid cells, although it did not sustain the growth of multipotential stem cells. Single-cell transfer experiments demonstrate that IL-3 supported the late stages of differentiation of neutrophils, macrophages, eosinophils, and megakaryocytes in the absence of lineage-specific factors. Therefore, IL-3 supports the differentiation of multilineage hemopoietic progenitors, and the terminal differentiation of most hemopoietic lineages, with the exception of the erythroid lineage.

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