Hepatitis B Vaccine in national immunization schedule: A preventive step in India

2011 ◽  
Vol 7 (12) ◽  
pp. 1387-1388 ◽  
Author(s):  
Ramesh Verma ◽  
Pardeep Khanna ◽  
Shankar Prinja ◽  
Meena Rajput ◽  
Suraj Chawla ◽  
...  
PEDIATRICS ◽  
1996 ◽  
Vol 97 (1) ◽  
pp. 143-143
Author(s):  

The Recommended Childhood Immunization Schedule for 1995 was developed by the Committee on Infectious Diseases (COID) of the American Academy of Pediatrics in collaboration with the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention (CDC) and the American Academy of Family Physicians (AAFP).1 Since the January 1995 publication, the AAP, ACIP, and AAFP have agreed on the following revisions: 1. The revised schedule is dated January-June 1996 and will be reprinted in July 1996 with any indicated changes. Incorporating dates in the chart will assure health care providers that they are using the most current schedule. 2. A column has been added to indicate that the second dose of hepatitis B vaccine can be administered at 1 month of age, provided that at least 1 month has elapsed since the first dose was given. Also, the doses of vaccine are provided in micrograms by individual product instead of volume, as several different concentrations of recombivax-HB (Merck, Sharp and Dohme) vaccine are available. 3. A bar has been added at 11-12 years of age to indicate that adolescents who have not previously received three doses of hepatitis B vaccine should initiate or complete the three-dose series. 4. Varicella zoster virus vaccine (Var) has been added to the schedule. In addition to the previously issued Academy recommendations, answers to commonly asked questions are addressed in a recent AAP News article.2,3 5. Information on inactivated poliomyelitis vaccine (IPV) has been added to reflect the Academy's current policy.


Author(s):  
C. F. T. Yoshida ◽  
C. Takahashi ◽  
L. A. C. Mercadante ◽  
I. F. Camargo ◽  
H. G. Schatzmayr

Immune response against hepatitis B vaccine (CLB 3mg) was evaluated in 59 hemodialysis patients and 20 occupational risk personnel. Seroconversion was induced in 52.5% and 70.0% respectively. Twelve months after the first dose, 37.5% of patients and 60.0% of occupational risk personnel had detectable anti-HBs level. Antibody level was expressed in sample ratio units (SRU). Considering only the responders, in the patients group 38.7% had a low anti-HBs response (2.1-9.9 SRU) 32.3% a medium response (10-99.9 SRU) and 29.0% a high response (>100 SRU) while in occupational risk personnel these values were 14.3%, 64.3% and 21.4% respectively. The authors suggest the use of HBV vaccines with more elevated HBsAg concentration or a reinforced immunization schedule to improve the anti-HBs response not only for patients but also for healthy persons.


2021 ◽  
Vol 46 (1) ◽  
pp. 4
Author(s):  
Sudip Bhattacharya ◽  
Ozden Gokdemir ◽  
MdAbu Bashar ◽  
Arulmani Thiyagarajan ◽  
Amarjeet Singh

Author(s):  
Dmitriy S. Yasakov ◽  
Natalya E. Tkachenko ◽  
Andrey P. Fisenko ◽  
Svetlana G. Makarova ◽  
Marina G. Vershinina ◽  
...  

Introduction. Vaccination is the primary method of preventing hepatitis B (HBV). Immunization performed according to the standard schedule often provides protective level of antibodies against HBV. However, the frequency deviation of the immunization schedule in children due to unjustified medical contraindication is the current problem in Russia. At the same time, there is currently no clear strategy for patients with significant deviations of the vaccination schedule, especially regarding extending the interval between the first and third administration of the HBV vaccine. The aim is to evaluate the immunological effects of vaccination against hepatitis B in the vaccination schedule deviation in healthy children and children with chronic diseases. Materials and methods. Eighty-one 0.7-11.7 year child with a disrupted schedule of vaccination against HBV was observed. The children were divided into two groups: children vaccinated within 12-35 months (group 1, n = 48) and children immunized more than 36 months after the first vaccination (group 2, n = 33). Children with chronic forms of pathology were included in both study groups. Blood tests for HBV antibodies after vaccination were performed 1-3 months after the third vaccination. Results. The average concentration of antibodies in the range of 10-1000 mMEd/ml in children of group 1 was significantly higher than in children of group 2 (p = 0.037). In addition, children with chronic diseases were significantly more likely to have an anti-HBs titer higher than 1000 mMEd/ml after the third vaccination than healthy children (p = 0.012). Conclusion. An increase in the interval between the first and third administration of the hepatitis B vaccine leads to a rise in the number of children who are not immune to hepatitis B. Chronic diseases fail to affect the immune response due to the introduction of the hepatitis B vaccine, even if the immunization schedule is disrupted.


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