scholarly journals Increased Expression of miR-146a in Children With Allergic Rhinitis After Allergen-Specific Immunotherapy

2016 ◽  
Vol 8 (2) ◽  
pp. 132 ◽  
Author(s):  
Xi Luo ◽  
Haiyu Hong ◽  
Jun Tang ◽  
Xingmei Wu ◽  
Zhibin Lin ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Specific Immunotherapy ◽  
Allergen Specific Immunotherapy

Effects of allergen-specific immunotherapy on functions of helper and regulatory T cells in patients with seasonal allergic rhinitis

2011 ◽  
Vol 22 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Cengiz Kirmaz ◽  
Ozlem Ozenturk Kirgiz ◽  
Papatya Bayrak ◽  
Ozge Yilmaz ◽  
Seda Vatansever ◽  
...  
Keyword(s):  
T Cells ◽  
Allergic Rhinitis ◽  
Regulatory T Cells ◽  
Seasonal Allergic Rhinitis ◽  
Specific Immunotherapy ◽  
Allergen Specific Immunotherapy

Long-term effects of allergen-specific subcutaneous immunotherapy for house dust mite induced allergic rhinitis

2017 ◽  
Vol 131 (11) ◽  
pp. 997-1001 ◽  
Author(s):  
E Sahin ◽  
D Dizdar ◽  
M E Dinc ◽  
A A Cirik
Keyword(s):  
Allergic Rhinitis ◽  
House Dust ◽  
House Dust Mite ◽  
Specific Immunotherapy ◽  
Subcutaneous Immunotherapy ◽  
Long Term Effects ◽  
Allergen Specific Immunotherapy ◽  
Dust Mite ◽  
Symptom Scores

AbstractBackground:Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based on a 10-year follow up of patients with allergic rhinitis.Methods:The study was conducted between 2001 and 2015. Skin prick test results and symptom scores were evaluated before (26 patients) and after 3 years (20 patients) of allergen-specific immunotherapy (using data from a previously published study), and 10 years after allergen-specific immunotherapy had ended (20 of 26 patients).Results:The symptom scores before allergen-specific immunotherapy were significantly higher than those obtained after 3 years of allergen-specific immunotherapy and 10 years after allergen-specific immunotherapy (p < 0.0175). There were no significant differences between the scores obtained at 3 years and 10 years after allergen-specific immunotherapy (p > 0.0175).Conclusion:Subcutaneous immunotherapy is an effective treatment for house dust mite induced allergic rhinitis.

GA2LEN/EAACI pocket guide for allergen-specific immunotherapy for allergic rhinitis and asthma

Allergy ◽  
2010 ◽  
Vol 65 (12) ◽  
pp. 1525-1530 ◽  
Author(s):  
T. Zuberbier ◽  
C. Bachert ◽  
P. J. Bousquet ◽  
G. Passalacqua ◽  
G. Walter Canonica ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Specific Immunotherapy ◽  
Allergen Specific Immunotherapy

The effects of allergen-specific immunotherapy on polymorphonuclear leukocyte functions in patients with seasonal allergic rhinitis

2005 ◽  
Vol 5 (4) ◽  
pp. 661-666 ◽  
Author(s):  
Ümran Soyoğul Gürer ◽  
Suna Büyüköztürk ◽  
Şükrü Palandüz ◽  
Erkan Rayaman ◽  
Bahattin Çolakoglu ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Polymorphonuclear Leukocyte ◽  
Seasonal Allergic Rhinitis ◽  
Specific Immunotherapy ◽  
Allergen Specific Immunotherapy

scholarly journals Mechanisms of allergen-specific immunotherapy for allergic rhinitis and food allergies

2020 ◽  
Vol 40 (4) ◽  
Author(s):  
Hiu Yan Lam ◽  
Vinay Tergaonkar ◽  
Kwang Seok Ahn
Keyword(s):  
Allergic Rhinitis ◽  
Specific Immunotherapy ◽  
Food Allergies ◽  
Potential Treatment ◽  
Allergen Specific Immunotherapy ◽  
Detailed Mechanism ◽  
Ige Mediated ◽  
Immunological Changes ◽  
Underlying Mechanisms ◽  
Specific Allergen

Abstract Allergen-specific immunotherapy (AIT) is currently the only potential treatment for allergies including allergic rhinitis (AR) and food allergies (FA) that can modify the underlying course of the diseases. Although AIT has been performed for over a century, the precise and detailed mechanism for AIT is still unclear. Previous clinical trials have reported that successful AIT induces the reinstatement of tolerance against the specific allergen. In this review, we aim to provide an updated summary of the knowledge on the underlying mechanisms of IgE-mediated AR and FA as well as the immunological changes observed after AIT and discuss on how better understanding of these can lead to possible identification of biomarkers and novel strategies for AIT.

scholarly journals Allergen-Specific Immunotherapy Against Allergic Respiratory Diseases

2020 ◽  
Vol 95 (6) ◽  
pp. 370-376
Author(s):  
Sung-Yoon Kang ◽  
Min-Suk Yang ◽  
Sang Min Lee ◽  
Sang Pyo Lee
Keyword(s):  
Allergic Rhinitis ◽  
Respiratory Diseases ◽  
Randomized Clinical Trials ◽  
Specific Immunotherapy ◽  
Term Treatment ◽  
Therapeutic Modality ◽  
Double Blind ◽  
Allergen Specific Immunotherapy ◽  
Long Term Treatment ◽  
Meta Analyses

Allergen-specific immunotherapy (AIT) can alter the natural course of an allergic disease. It is widely held that the efficacy of a given therapeutic modality should be proven by well-designed double-blind placebo-controlled randomized clinical trials and meta-analyses. In this article, the therapeutic efficacy of AIT for allergic respiratory diseases, such as allergic rhinitis and asthma, is reviewed. In addition, potential clinical and experimental predictors of the treatment response are reviewed for AITs requiring long-term treatment, and for some allergic rhinitis and asthma patients who show no response to AIT.

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