Sporidesmium sclerotivorum Uecker, Ayers, & Adams is mycoparasite of sclerotia with potential for biocontrol. Sclerotia of fungi in the sclerotial lineage of the Sclerotiniaceae, including species of Sclerotinia, Botrytis, Amphobotrys, and Monilinia, stimulated germination of macroconidia of Sp. sclerotivorum. The mycoparasite readily colonized sclerotia of Sclerotinia spp. and Amphobotrys ricini (Buchwald) Hennebert both in soil and in vitro. Sclerotia of Botrytis spp. were parasitized only occasionally, and some Sclerotiniaceae were not parasitized. The limits on the ability of Sp. sclerotivorum to parasitize sclerotia support its classification as fastidious. Not even the first step in mycoparasitism, germination of Sp. sclerotivorum macroconidia, was triggered by sclerotia of fungi outside of the family. Amphobotrys ricini, the causal agent of gray mold of castor bean (Ricinus communis L.), is a newly recognized host of Sp. sclerotivorum, and sclerotia of this pathogen were destructively colonized by the mycoparasite.Key words: Amphobotrys ricini, biocontrol, host-parasite interaction, Sclerotiniaceae, Sclerotium cepivorum, signal.