Relationships among the Genotypes of Malassezia Globosa Colonizing Patients with Atopic Dermatitis, the Clinical Severity of the Disease, and the Level of Specific IgE Antibodies

2014 ◽  
Vol 4 (5) ◽  
Author(s):  
Otomi Cho
Keyword(s):  
Atopic Dermatitis ◽  
Specific Ige ◽  
Clinical Severity ◽  
Ige Antibodies ◽  
Malassezia Globosa ◽  
Specific Ige Antibodies ◽  
Severity Of The Disease

scholarly journals Anti-Malassezia-Specific IgE Antibodies Production in Japanese Patients with Head and Neck Atopic Dermatitis: Relationship between the Level of Specific IgE Antibody and the Colonization Frequency of Cutaneous Malassezia Species and Clinical Severity

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Enshi Zhang ◽  
Takafumi Tanaka ◽  
Mami Tajima ◽  
Ryoji Tsuboi ◽  
Hiroshi Kato ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Head And Neck ◽  
Japanese Patients ◽  
Specific Ige ◽  
Clinical Severity ◽  
Ige Antibodies ◽  
Malassezia Species ◽  
Colonization Frequency ◽  
Specific Ige Antibodies ◽  
Species Specific

Atopic dermatitis of the head and neck (HNAD) is recognized as a separate condition. Malassezia, the predominant skin microbiota fungus, is considered to exacerbate atopic dermatitis (AD), especially HNAD. In the present study, we investigated the relationships between the levels of specific IgE antibodies, colonization frequency of eight predominant Malassezia species, and clinical severity in 61 patients with HNAD (26 mild, 24 moderate, and 11 severe cases). As clinical severity increased, the levels of specific IgE antibodies against eight Malassezia species also increased. Species diversity of the Malassezia microbiota in scale samples from patients was analyzed by nested PCR using species-specific primers. The clinical severity of HNAD was correlated with the total level of specific IgE antibodies against Malassezia species and the number of Malassezia species detected.

scholarly journals CLINICAL SIGNIFICANCE OF DETERMINATION OF IGE ANTIBODIES TO STAPHYLOCOCCUS AUREUS AND MALASSEZIA SPECIES IN SERUM OF CHILDREN WITH ATOPIC DERMATITIS

2018 ◽  
Vol 63 (4) ◽  
pp. 84-88
Author(s):  
T. S. Okuneva ◽  
M. V. Kushnareva ◽  
A. N. Pampura ◽  
E. E. Varlamov ◽  
N. G. Konyukova
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Clinical Significance ◽  
Specific Ige ◽  
Frequency Of Occurrence ◽  
Ige Antibodies ◽  
Malassezia Species ◽  
Specific Ige Antibodies ◽  
Malassezia Spp

We studied the frequency of occurrence and concentration of allergen-specific IgE antibodies (asIgE) to enterotoxins A, B, C and TSST-1 of Staphylococcus aureus and Malassezia spp. in the serum of children with atopic dermatitis in the acute period of the disease. The determination of asIgE levels was performed in 84 children aged from 5 months to 17 years using the immunochemiluminescent method on the UniCAP 100 analyzer (Phadia, Sweden). The level of asIgE was evaluated on a scale of 6 classes.The sensitization to S. aureus enterotoxins was detected in 29 children with аsIgE concentration from 0.35 to 25.8 kU/L (I–IV classes). In 16 children were observed 8 polysensitization options to S. aureus allergens. Combinations of asIgE to A + B and A + B + C enterotoxins were most common – in every fourth and fifth child,respectively. Sensitization to Malassezia spp. was observed in 41 children with concentration from 0.38 to 98.9 KU/L (I–V classes). Polysensitization to both S. aureus and Malassezia spp. allergens was observed in one of two children. A higher degree of sensitisation to Malassezia spp allergens has been established compared to S. aureus.Conclusion. To improve the specific diagnostics of atopic dermatitis, it is advisable to examine the serum for a complete panel of recombinant S. aureus enterotoxins in combination with the determination of asIgE to Malassezia spp. 

Specific IgE antibodies and serum eosinophil cationic protein in children with atopic dermatitis alone

1994 ◽  
Vol 36 (2) ◽  
pp. 146-149 ◽  
Author(s):  
ATSUO URISU ◽  
YASUTO KONDO ◽  
EIKO WADA ◽  
FUMIYA HORIBA ◽  
MITSUTOSI TSURUTA ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Eosinophil Cationic Protein ◽  
Specific Ige ◽  
Cationic Protein ◽  
Ige Antibodies ◽  
Specific Ige Antibodies

scholarly journals Evaluation of criteria for diagnosis of atopic dermatitis and detection of allergen specific IgE antibodies in dogs allergic to Ambrosia artemisiifolia pollen

2013 ◽  
Vol 63 (4) ◽  
pp. 437-451 ◽  
Author(s):  
Natalija Milcic-Matic ◽  
Jana Ognjenovic ◽  
Lidija Burazer ◽  
G. Blagojevic ◽  
N. Popovic ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Specific Ige ◽  
Ambrosia Artemisiifolia ◽  
Ige Antibodies ◽  
Specific Ige Antibodies ◽  
Criteria For Diagnosis

The sweat of patients with atopic dermatitis contains specific IgE antibodies to inhalant allergens

1996 ◽  
Vol 21 (5) ◽  
pp. 347-350 ◽  
Author(s):  
K. JUNG ◽  
G. SCHLENVOIGT ◽  
K. LADWIG ◽  
D. HERRMANN ◽  
C. MOTHS ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Specific Ige ◽  
Ige Antibodies ◽  
Specific Ige Antibodies ◽  
Inhalant Allergens

Staphylococcal enterotoxin-specific IgE antibodies in atopic dermatitis

2004 ◽  
Vol 46 (3) ◽  
pp. 337-341 ◽  
Author(s):  
Fumihito Ide ◽  
Tomoyo Matsubara ◽  
Miho Kaneko ◽  
Takashi Ichiyama ◽  
Tokuko Mukouyama ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Specific Ige ◽  
Staphylococcal Enterotoxin ◽  
Ige Antibodies ◽  
Specific Ige Antibodies

Specific IgE Antibodies in Young Children with Atopic Dermatitis - Correlation of Multiple Allergen Simultaneous Immunoblot Test and ImmunoCap System

2016 ◽  
Vol 62 (05/2016) ◽  
Author(s):  
Ewa Konopka ◽  
Aldona Ceregra ◽  
Elzbieta Maciorkowska ◽  
Barbara Surowska ◽  
Ilona Trojanowska ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Young Children ◽  
Specific Ige ◽  
Ige Antibodies ◽  
Specific Ige Antibodies

scholarly journals Staphylococcal superantigen-specific IgE antibodies: degree of sensitization and association with severity of asthma

2016 ◽  
Vol 42 (5) ◽  
pp. 356-361 ◽  
Author(s):  
José Elabras Filho ◽  
Fernanda Carvalho de Queiroz Mello ◽  
Omar Lupi ◽  
Blanca Elena Rios Gomes Bica ◽  
José Angelo de Souza Papi ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Persistent Asthma ◽  
Serum Levels ◽  
Specific Ige ◽  
Clinical Severity ◽  
University Hospital ◽  
Ige Antibodies ◽  
Staphylococcal Toxin ◽  
Quantitative Results ◽  
Specific Ige Antibodies

ABSTRACT Objective: To determine the presence of staphylococcal superantigen-specific IgE antibodies and degree of IgE-mediated sensitization, as well as whether or not those are associated with the severity of asthma in adult patients. Methods: This was a cross-sectional study involving outpatients with asthma under treatment at a tertiary care university hospital in the city of Rio de Janeiro, Brazil. Consecutive patients were divided into two groups according to the severity of asthma based on the Global Initiative for Asthma criteria: mild asthma (MA), comprising patients with mild intermittent or persistent asthma; and moderate or severe asthma (MSA). We determined the serum levels of staphylococcal toxin-specific IgE antibodies, comparing the results and performing a statistical analysis. Results: The study included 142 patients: 72 in the MA group (median age = 46 years; 59 females) and 70 in the MSA group (median age = 56 years; 60 females). In the sample as a whole, 62 patients (43.7%) presented positive results for staphylococcal toxin-specific IgE antibodies: staphylococcal enterotoxin A (SEA), in 29 (20.4%); SEB, in 35 (24.6%); SEC, in 33 (23.2%); and toxic shock syndrome toxin (TSST), in 45 (31.7%). The mean serum levels of IgE antibodies to SEA, SEB, SEC, and TSST were 0.96 U/L, 1.09 U/L, 1.21 U/L, and 1.18 U/L, respectively. There were no statistically significant differences between the two groups in terms of the qualitative or quantitative results. Conclusions: Serum IgE antibodies to SEA, SEB, SEC, and TSST were detected in 43.7% of the patients in our sample. However, neither the qualitative nor quantitative results showed a statistically significant association with the clinical severity of asthma.

Sign in / Sign up

Export Citation Format

Share Document