Latest advances in artificial intelligence, computer-aided cancer detection and machine learning in radiology and oncology

2018 ◽  
Vol 07 ◽  
Author(s):  
Sanjay Gandhi
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Cancer Detection ◽  
Computer Aided

Virtual Screening Meets Deep Learning

2018 ◽  
Vol 15 (1) ◽  
pp. 6-28 ◽  
Author(s):  
Javier Pérez-Sianes ◽  
Horacio Pérez-Sánchez ◽  
Fernando Díaz
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Virtual Screening ◽  
Great Increase ◽  
New Drugs ◽  
Learning Approach ◽  
Screening Strategies ◽  
Computer Aided ◽  
Recent Developments

Background: Automated compound testing is currently the de facto standard method for drug screening, but it has not brought the great increase in the number of new drugs that was expected. Computer- aided compounds search, known as Virtual Screening, has shown the benefits to this field as a complement or even alternative to the robotic drug discovery. There are different methods and approaches to address this problem and most of them are often included in one of the main screening strategies. Machine learning, however, has established itself as a virtual screening methodology in its own right and it may grow in popularity with the new trends on artificial intelligence. Objective: This paper will attempt to provide a comprehensive and structured review that collects the most important proposals made so far in this area of research. Particular attention is given to some recent developments carried out in the machine learning field: the deep learning approach, which is pointed out as a future key player in the virtual screening landscape.

scholarly journals Retrosynthetic Accessibility Score (RAscore) - Rapid Machine Learned Synthesizability Classification from AI Driven Retrosynthetic Planning

2020 ◽  
Author(s):  
Amol Thakkar ◽  
Veronika Chadimova ◽  
Esben Jannik Bjerrum ◽  
Ola Engkvist ◽  
Jean-Louis Reymond
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Virtual Screening ◽  
Generative Models ◽  
Synthetic Route ◽  
Synthetic Accessibility ◽  
Wide Range ◽  
Computer Aided ◽  
Synthesis Planning ◽  
Retrosynthetic Analysis

<p>Computer aided synthesis planning (CASP) is part of a suite of artificial intelligence (AI) based tools that are able to propose synthesis to a wide range of compounds. However, at present they are too slow to be used to screen the synthetic feasibility of millions of generated or enumerated compounds before identification of potential bioactivity by virtual screening (VS) workflows. Herein we report a machine learning (ML) based method capable of classifying whether a synthetic route can be identified for a particular compound or not by the CASP tool AiZynthFinder. The resulting ML models return a retrosynthetic accessibility score (RAscore) of any molecule of interest, and computes 4,500 times faster than retrosynthetic analysis performed by the underlying CASP tool. The RAscore should be useful for the pre-screening millions of virtual molecules from enumerated databases or generative models for synthetic accessibility and produce higher quality databases for virtual screening of biological activity. </p>

Artificially Intelligent Physiotherapy

2021 ◽  
Vol 10 (1) ◽  
pp. 77-88
Author(s):  
Sachin Pandurang Godse ◽  
Shalini Singh ◽  
Sonal Khule ◽  
Shubham Chandrakant Wakhare ◽  
Vedant Yadav
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Range Of Motion ◽  
Real Time ◽  
Severe Pain ◽  
User Performance ◽  
Computer Aided ◽  
To Come ◽  
And Performance ◽  
At Home

Physiotherapy is the trending medication for curing bone-related injuries and pain. In many cases, due to sudden jerks or accidents, the patient might suffer from severe pain. Therefore, it is the miracle medication for curing patients. The aim here is to build a framework using artificial intelligence and machine learning for providing patients with a digitalized system for physiotherapy. Even though various computer-aided assessment of physiotherapy rehabilitation exist, recent approaches for computer-aided monitoring and performance lack versatility and robustness. In the authors' approach is to come up with proposition of an application which will record patient physiotherapy exercises and also provide personalized advice based on user performance for refinement of therapy. By using OpenPose Library, the system will detect angle between the joints, and depending upon the range of motion, it will guide patients in accomplishing physiotherapy at home. It will also suggest to patients different physio-exercises. With the help of OpenPose, it is possible to render patient images or real-time video.

scholarly journals Artificial intelligence, machine learning, computer-aided diagnosis, and radiomics: advances in imaging towards to precision medicine

2019 ◽  
Vol 52 (6) ◽  
pp. 387-396 ◽  
Author(s):  
Marcel Koenigkam Santos ◽  
José Raniery Ferreira Júnior ◽  
Danilo Tadao Wada ◽  
Ariane Priscilla Magalhães Tenório ◽  
Marcello Henrique Nogueira Barbosa ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Diagnostic Imaging ◽  
Precision Medicine ◽  
Quantitative Information ◽  
Computer Aided Diagnosis ◽  
Rapid Expansion ◽  
Computer Aided ◽  
The Impact ◽  
Aided Diagnosis

Abstract The discipline of radiology and diagnostic imaging has evolved greatly in recent years. We have observed an exponential increase in the number of exams performed, subspecialization of medical fields, and increases in accuracy of the various imaging methods, making it a challenge for the radiologist to “know everything about all exams and regions”. In addition, imaging exams are no longer only qualitative and diagnostic, providing now quantitative information on disease severity, as well as identifying biomarkers of prognosis and treatment response. In view of this, computer-aided diagnosis systems have been developed with the objective of complementing diagnostic imaging and helping the therapeutic decision-making process. With the advent of artificial intelligence, “big data”, and machine learning, we are moving toward the rapid expansion of the use of these tools in daily life of physicians, making each patient unique, as well as leading radiology toward the concept of multidisciplinary approach and precision medicine. In this article, we will present the main aspects of the computational tools currently available for analysis of images and the principles of such analysis, together with the main terms and concepts involved, as well as examining the impact that the development of artificial intelligence has had on radiology and diagnostic imaging.

A Review of Artificial Intelligence in Cerebrovascular Disease Imaging: Applications and Challenges

2021 ◽  
Vol 19 ◽  
Author(s):  
Xi Chen ◽  
Yu Lei ◽  
Jiabin Su ◽  
Heng Yang ◽  
Wei Ni ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Medical Imaging ◽  
Arteriovenous Malformation ◽  
Moyamoya Disease ◽  
Cerebrovascular Diseases ◽  
Machine Learning Techniques ◽  
Computer Aided Detection ◽  
Computer Aided

Background: A variety of emerging medical imaging technologies based on artificial intelligence have been widely applied in many diseases, but they are still limited used in the cerebrovascular field even though the diseases can lead to catastrophic consequences. Objective: This work aims to discuss the current challenges and future directions of artificial intelligence technology in cerebrovascular diseases through reviewing the existing literature related to applications in terms of computer-aided detection, prediction and treatment of cerebrovascular diseases. Methods: Based on artificial intelligence applications in four representative cerebrovascular diseases including intracranial aneurysm, arteriovenous malformation, arteriosclerosis and moyamoya disease, this paper systematically reviews studies published between 2006 and 2021 in five databases: National Center for Biotechnology Information, Elsevier Science Direct, IEEE Xplore Digital Library, Web of Science and Springer Link. And three refinement steps were further conducted after identifying relevant literature from these databases. Results: For the popular research topic, most of the included publications involved computer-aided detection and prediction of aneurysms, while studies about arteriovenous malformation, arteriosclerosis and moyamoya disease showed an upward trend in recent years. For the algorithms, both conventional machine learning and deep learning algorithms were utilized in these publications, but machine learning techniques accounted for a larger proportion. Conclusion: Algorithms related to artificial intelligence, especially deep learning, are promising tools for medical imaging analysis and will enhance the performance of computer-aided detection, prediction and treatment of cerebrovascular diseases.

scholarly journals Machine Learning Method for Pancreatic Cancer Detection using Naïve Bayes and Decision Tree Algorithm

2020 ◽  
Vol 9 (7) ◽  
pp. 1137-1141
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Pancreatic Cancer ◽  
Cancer Detection ◽  
Pancreatic Tumors ◽  
Hybrid Technique ◽  
Mri Scan ◽  
Morphological Process ◽  
Clustering Model ◽  
Machine Learning Approach

Machine Learning is the study of algorithms and application of artificial intelligence. Artificial Intelligence is said to be the superset of machine learning. It aims to develop those programs which can learn and improves it upon increasing experience. It is designed to learn by itself. The aim is to detect pancreatic cancer using machine learning approach. Pancreas is responsible for secreting insulin which helps to control the blood glucose level in the human body. The paper aims to detect pancreatic cancer with the help of machine learning. The tumor is detected using image processing and is to be detected at the premature stage so that proper medication and treatment can be provided to increase the survival rate of the patient. The MRI image of pancreas obtained after MRI scan will be preprocessed and its noise is removed. The segmentation of MRI images will be performed using FCM algorithm. The tumor present in the image will be detected with the help of morphological process and multi clustering model. After Segmentation the image will be divided into various regions. With the help of the hybrid technique the primary and secondary regions are compressed and are used for telemedicine application. DWT is used for DE noising the image. GLCM features are extracted. The image then compared with the database images of pancreatic tumors and is classified as abnormal and normal with the help of BPN based classifier. The image is classified into abnormal and normal. The malignant image is considered as abnormal. The abnormal image is then segmented using SFCM and tumor part is clustered. After clustering the tumor part validation about the presence of pancreatic cancer is given.

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