Improvement of Fertilization Rates of In Vitro Cultured Human Embryos by Exposure to Sound Vibrations

2015 ◽  
Vol 03 (04) ◽  
Author(s):  
M Lopez Teijon ◽  
C Castello ◽  
M Asensio
Keyword(s):  
Human Embryos ◽  
Fertilization Rates

scholarly journals IN VITRO PERI-IMPLANTATION DEVELOPMENT OF GOOD QUALITY HUMAN EMBRYOS IS AFFECTED BY BLASTOCYST MORPHOLOGICAL GRADE AND MATERNAL AGE

2020 ◽  
Vol 114 (3) ◽  
pp. e315
Author(s):  
Deirdre M. Logsdon ◽  
Rachel C. West ◽  
Rebecca Kile ◽  
Courtney K. Grimm ◽  
Mandy G. Katz-Jaffe ◽  
...  
Keyword(s):  
Maternal Age ◽  
Human Embryos

Advancing maternal age compromises control of cell cycle checkpoint for aneuploidies in human embryos cultured in vitro

2002 ◽  
Vol 78 ◽  
pp. S181
Author(s):  
H Asakura ◽  
K.P Katayama ◽  
E.F Stehlik ◽  
J.C Stehlik ◽  
K Winchester-Peden
Keyword(s):  
Cell Cycle ◽  
Maternal Age ◽  
Cell Cycle Checkpoint ◽  
Human Embryos ◽  
Cycle Checkpoint

scholarly journals Why we should not extend the 14-day rule

2021 ◽  
pp. medethics-2021-107317
Author(s):  
Bruce Philip Blackshaw ◽  
Daniel Rodger
Keyword(s):  
Scientific Research ◽  
Human Embryos ◽  
Limit Pressure ◽  
Potential Benefits

The 14-day rule restricts the culturing of human embryos in vitro for the purposes of scientific research for no longer than 14 days. Since researchers recently developed the capability to exceed the 14-day limit, pressure to modify the rule has started to build. Sophia McCully argues that the limit should be extended to 28 days, listing numerous potential benefits of doing so. We contend that McCully has not engaged with the main reasons why the Warnock Committee set such a limit, and these still remain valid. As a result, her case for an extension of the 14-day rule is not persuasive.

Comparison of implantation and early development of human embryos fertilized in vitro versus in vivo using transvaginal ultrasound.

1991 ◽  
Vol 10 (1) ◽  
pp. 31-35 ◽  
Author(s):  
A Pellicer ◽  
C Calatayud ◽  
F Miro ◽  
R M Castellvi ◽  
A Ruiz ◽  
...  
Keyword(s):  
Early Development ◽  
Transvaginal Ultrasound ◽  
Human Embryos

scholarly journals Protocol for controlled modeling of human epiblast and amnion development using stem cells

2019 ◽  
Author(s):  
Yi Zheng ◽  
Jianping Fu
Keyword(s):  
Stem Cells ◽  
Primordial Germ Cells ◽  
Primitive Streak ◽  
Human Embryos ◽  
Vitro Fertilization ◽  
Human Embryology ◽  
Post Implantation ◽  
Advance Knowledge ◽  
Early Human

Abstract Due to the inaccessibility of post-implantation human embryos and the restriction on in-vitro fertilization (IVF) embryos cultured beyond 14 days, the knowledge of early post-implantation human embryogenesis remains extremely limited. Recently, we have developed a microfluidic in-vitro platform, based on human pluripotent stem cells (hPSCs), which is capable of recapitulating several key developmental landmarks of early human post-implantation embryonic development, including lumenogenesis of the epiblast (EPI), amniogenesis, and specification of primordial germ cells (PGCs) and of primitive streak (PS) cells. Given its controllability and reproducibility, the microfluidic platform provides a powerful experimental platform to advance knowledge of human embryology and reproduction. This protocol describes the preparation of the microfluidic device and its implementation for modeling human post-implantation epiblast and amnion development using hPSCs.

scholarly journals Robust Metabolomics Approach For The Evaluation Of Human Embryos From In-Vitro Fertilization.

2021 ◽  
Author(s):  
Cecilia Figoli ◽  
Marcelo Garcea ◽  
Claudio Bisioli ◽  
Valeria Tafintseva ◽  
Volha Shapaval ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
In Vitro Fertilization ◽  
Selection Criterion ◽  
Human Embryos ◽  
Spectral Features ◽  
Success Rates ◽  
Vitro Fertilization ◽  
Main Challenge ◽  
Culture Supernatants

Abstract The identification of the most competent embryos for transfer to the uterus constitutes the main challenge of in-vitro fertilization (IVF). We established a metabolomic-based approach applying Fourier Transform Infrared spectroscopy (FTIR) on 130 samples of 3-days embryo culture supernatants from 26 embryos that implanted and 104 that failed. Examining the internal structure of the data by unsupervised multivariate analysis, it was observed that the supernatants of nonimplanted embryos contained highly heterogeneous spectral features. These features were overlapping with metabolic-implantation fingerprints, thus demonstrating that in establishing embryo-assessment models a one-class modelling involving only the samples with positive-implantation outcomes should be applied. Analysis of variance confirmed that the women´s age (>40 years) undermined the implantation of the embryos exhibiting implantation metabolomics, and also that constituted a condition triggering embryos to express nonimplantation metabolomics. We conclude that IVF-success rates can be significantly improved if FTIR spectroscopy is used as an embryo-selection criterion.

scholarly journals élethez való jog néhány jogelméleti kérdéséről

2013 ◽  
Vol 10 (1) ◽  
pp. 65-73
Author(s):  
Judit Vörös
Keyword(s):  
Case Law ◽  
Point Of View ◽  
In Vitro Fertilisation ◽  
Human Embryos ◽  
Constitutional Court ◽  
Right To Life ◽  
The Subject ◽  
The Right

Nowadays in vitro fertilisation raises relevant controversies at the point of view of jurisprudence as well. The distinct approximations of in vitro embryos, such as to be considered as personae or objects, are also resources of several theoretical and pragmatical questions. It is essential to give a compendious summary about what kind of jurisprudental environment had been contributed to the intrumental comprehension of human embryos too, otherwise it is difficult to understand the scientific quandaries connected to the subject correctly. Merely thereafter the international and the Hungarian regulation of in vitro embryo’s status seems to able to be dissected, in particular the case-law of the Hungarian Constitutional Court related to the right to life and the constitutional funds of the oncurrent re-regulation in our country.

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