scholarly journals Optimizing Adjuvant Radiation Planning Outcomes in Patients with Synchronous Bilateral Breast Cancer

2021 ◽  
Vol 10 (03) ◽  
pp. 110-119
Author(s):  
Mohamed M. Alhefny ◽  
Hany S. Attallah ◽  
Mahmoud Abdallah ◽  
Adel Yassin ◽  
Khaled M. El-Shahat ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bilateral Breast Cancer ◽  
Adjuvant Radiation ◽  
Synchronous Bilateral Breast Cancer ◽  
Radiation Planning

scholarly journals Synchronous Bilateral Breast Cancer: Implications for Adjuvant Radiation

2019 ◽  
pp. 1-3
Author(s):  
Susanna Nguy ◽  
Naamit K. Gerber
Keyword(s):  
Breast Cancer ◽  
Early Stage ◽  
Bilateral Breast Cancer ◽  
Left Breast ◽  
Adjuvant Radiation ◽  
Axillary Lymph ◽  
Nodal Disease ◽  
Excellent Teaching ◽  
Synchronous Bilateral Breast Cancer ◽  
Nodal Burden

We present the case of a 55-year old postmenopausal female with bilateral early stage clinically node negative breast cancer who was treated with bilateral lumpectomy with axillary lymph node dissection revealing N1a nodal disease in her right breast with extra-nodal extension and micrometastatic disease in her left breast. Given the controversy in management for low nodal burden for macroscopic and microscopic nodal disease, we review the key trials in regional nodal management that have included patients with low nodal burden to explain our reasoning for treatment decisions. Our patient was treated with both hypofractionation and conventional treatment. She is an excellent teaching case to demonstrate how much of an impact the decision regarding fractionation can have on long term breast cosmesis and toxicity.

scholarly journals Quantitative and dosimetric analysis for treating synchronous bilateral breast cancer using two radiotherapy planning techniques

2021 ◽  
Vol 27 (3) ◽  
pp. 201-206
Author(s):  
Özlem Mermut ◽  
Aysun Ozsoy Ata ◽  
Didem Can Trabulus
Keyword(s):  
Breast Cancer ◽  
Early Stage ◽  
Organs At Risk ◽  
Bilateral Breast Cancer ◽  
Radiotherapy Planning ◽  
Conformity Index ◽  
Treatment Unit ◽  
Significant Difference ◽  
Synchronous Bilateral Breast Cancer ◽  
The Right

Abstract Objective: We compared mono-isocenter and dual-isocenter plans in synchronous bilateral breast cancer (SBBC), which is defined as tumours occurring simultaneously in both breasts, and evaluated the effects of these differences in plans on organs-at-risk (OARs). Materials and methods: We evaluated 10 women with early stage, nod negative (Tis-2N0M0) SBBC. The treatment dose was determined to be 50 Gy. We used mean dose and VXGy to evaluate the OARs. To evaluate the effectiveness of treatment plans, Homogeneity index (HI), conformity index (CI) and sigma index (SI) and monitor units (MU) of monoisocenter (MIT) and dual-isocenter (DIT) plans were compared. During bilateral breast planning, for the single-centre plan, the isocenter was placed at the center of both breasts at a depth of 3-4 cm. For the two-center plan, dual-isocenters were placed on the right and left breasts. Results: No significant difference between the techniques in terms of the scope of the target volume was observed. Statistically significant results were not achieved in MIT and DIT plans for OARs. Upon comparing MIT and DIT, the right-side monitor unit (MU) value in DIT (p = 0.011) was statistically significantly lower than that in MIT. Upon comparing right-left side MIT and DIT, the MU value (p = 0.028) was significantly lower in DIT than MIT. Conclusion: SBBC irradiation is more complex than unilateral breast radiotherapy. No significant difference between both techniques and OARs was observed. However, we recommend MIT as a priority technique due to the ability to protect OARs, ease of administration during treatment, and the fact that the patient stays in the treatment unit for a shorter period of time.

141 Breast-conserving therapy (BCT) in stage I–II synchronous bilateral breast cancer (SBBC)

1995 ◽  
Vol 32 ◽  
pp. 211 ◽  
Author(s):  
Smitha V. Gollamudi ◽  
Rebecca S. Gelman ◽  
Gloria Peiro ◽  
Lindsey Schneider ◽  
James L. Connolly ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bilateral Breast Cancer ◽  
Breast Conserving Therapy ◽  
Stage I ◽  
Synchronous Bilateral Breast Cancer

A CASE OF SYNCHRONOUS BILATERAL BREAST CANCER WITH DISCORDANT ESTROGEN RECEPTOR STATUS

2021 ◽  
pp. 72-73
Author(s):  
B Santhi ◽  
S Savitha ◽  
S Sujitha
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Estrogen Receptor Status ◽  
Bilateral Breast Cancer ◽  
Breast Conservation ◽  
Time Interval ◽  
Rare Entity ◽  
Synchronous Bilateral Breast Cancer ◽  
Metachronous Breast Cancer ◽  
Degree Of Differentiation

Synchronous bilateral breast cancer is dened as two tumours diagnosed within 6 month interval and those above 6 months termed as metachronous breast cancer though there is difference in time interval specied by various clinicians. SBBC is a rare entity with incidence of 0.3 – 1.2% though it is recently increasing due to improved life expectancy after treatment and routine use of contralateral mammography. It is considered that synchronous breast tumours are independent tumours than to be secondary to metastatic spread from primary. Presence of indraductal component, different histology and different degree of differentiation implies that 2 they are independent tumors. Mostly women with BSBC are treated with aggressive measures as they are thought to be aggressive. Recently overall consensus is that bilateral breast cancer is amenable to breast conservation surgeries 1 without compromising surviva

Determining the prognosis of women with synchronous bilateral breast cancer

2007 ◽  
Vol 33 (9) ◽  
pp. 1123-1123
Author(s):  
T IRVINE ◽  
D ALLEN ◽  
C GILLETT ◽  
I FENTIMAN ◽  
H HAMED
Keyword(s):  
Breast Cancer ◽  
Bilateral Breast Cancer ◽  
Synchronous Bilateral Breast Cancer

Trends in the diagnosis of synchronous bilateral breast cancer

2018 ◽  
Vol 44 (6) ◽  
pp. 909
Author(s):  
Yan Yu Tan ◽  
Mihir Chandarana ◽  
Frank Liaw ◽  
Sadaf Jafferbhoy ◽  
Sekhar Marla ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bilateral Breast Cancer ◽  
Synchronous Bilateral Breast Cancer
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