scholarly journals Antibiotic Resistance Phenotypes of <i>Enterobacteriaceae</i> Isolated from Household Wastewater in Brazzaville, Republic of Congo

2021 ◽  
Vol 11 (01) ◽  
pp. 27-36
Author(s):  
Rachel Moyen ◽  
Tarcisse Baloki Ngoulou ◽  
Etienne Nguimbi ◽  
Gabriel Ahombo
Keyword(s):  
Antibiotic Resistance ◽  
Republic Of Congo ◽  
Household Wastewater

scholarly journals Results from the Survey of Antibiotic Resistance (SOAR) 2011–14 in the Democratic Republic of Congo, Ivory Coast, Republic of Senegal and Kenya

2016 ◽  
Vol 71 (suppl 1) ◽  
pp. i21-i31 ◽  
Author(s):  
A. Kacou-Ndouba ◽  
G. Revathi ◽  
P. Mwathi ◽  
A. Seck ◽  
A. Diop ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Ivory Coast ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Republic Of Congo

scholarly journals General practitioners’ knowledge, attitudes and practices on antibiotic prescribing for acute respiratory infections in children in Lubumbashi, Democratic Republic of Congo

2020 ◽  
Vol 4 (1) ◽  
pp. 011-017
Author(s):  
Wembonyama Kasongo Aubin Ndjadi ◽  
Mukuku Olivier ◽  
Kanteng Gray A-Wakamb ◽  
Shongo Mick Ya-Pongombo ◽  
Mutombo André Kabamba ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
General Practitioners ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Antibiotic Prescribing ◽  
Motivation To Change ◽  
Cross Sectional Survey ◽  
Republic Of Congo ◽  
Attitudes And Practices ◽  
Knowledge Attitudes And Practices

Objective: To assess the knowledge, attitudes and practices declared among general practitioners (GPs) concerning the use of antibiotics for the treatment of ARI in children under 5 years in Lubumbashi. Methods: A cross-sectional survey was conducted to assess the level of knowledge, attitude and practices concerning antibiotic prescribing among 67 GPs working in the pediatric setting in various health structures in Lubumbashi city, in the Democratic Republic of Congo. Data were collected from April 1st to June 30th, 2020. Results: GPs had limited knowledge about antibiotic prescriptions (mean of 46% correct answers to 8 questions). Although they are generally concerned about antibiotic resistance (mean ± SD = 0.50 ± 0.68), and are unwilling to submit to pressure to prescribe antibiotics to meet patient demands and expectations (mean ± SD = –1.78 ± 0.31) and the requirements to prescribe antibiotics for fear of losing patients (mean ± SD = –1.67 ± 0.47), there was a lack of motivation to change prescribing practices (mean ± SD = −0.37 ± 0.94) and strong agreement that they themselves should take responsibility for tackling antibiotic resistance (mean ± SD = 1.24 ± 0.74). Multiple linear regression results showed that higher knowledge scores were associated with less avoidance of responsibility when prescribing antibiotics (β = 0.919; p = 0.000). Conclusion: To curb the over-prescription of antibiotics, it is not enough to improve knowledge in itself. The lack of motivation of physicians to change must be addressed through a systematic approach. These data show the need for interventions that support the rational prescribing of antibiotics.

scholarly journals Biofilm Formation and Antibiotic resistance of Enterobacteriaceae isolates from Surgical Site infections in Hôpital de Référence Saint Joseph, Kinshasa, Democratic Republic of Congo

2020 ◽  
Author(s):  
Jean-Marie Liesse Iyamba ◽  
Rodriguez Musomoni Mabankama ◽  
Cyprien Mbundu Lukukula ◽  
Joseph Welo Unya ◽  
Daniel Tassa Okombe ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Biofilm Formation ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Surgical Site Infections ◽  
Multidrug Resistant ◽  
Diffusion Method ◽  
Republic Of Congo ◽  
E Coli ◽  
Multidrug Resistant Organisms

Abstract Background: Enterobacteriaceae are one of the most predominant pathogen in surgical site infections. In recent years we oberved increase in resistance among bacteria from surgical site infections. The aim of this study was to evaluate antimicrobial suceptibility pattern of Enterobacteriaceae isolates from surgical site infections, the biofilm formation and the production of OXA-48 carbapenemase.Methods: A total of 41 Enterobacteriaceae (19 Escherchia coli, 8 Enterobacter sp., 9 Citrobacter sp., and 5 Serratia sp. ) clinical isolates were collected from patients with SSI in Hôpital Saint Joseph (Kinshasa) for diagnostic purposes. The pus samples were cultured and the antibiotic susceptibility profile of the isolates were determined by disk-diffusion method following Clinical and Laboratory Standards Institute 2012 recommendations. OXA-48-producing Enterobacteriaceae were detected using ChromaticTM OXA-48 chromogenic medium. Crystal Violet Staining Method was used to assess the ability of bacteria strains to form a biofilm. Results: All Enterobacteriacea isolates studied were biofilm producers and highly resistant to the majority of antibiotics tested. E. coli, Enterobacter sp., Citrobacter sp., and Serratia sp. were 100 % resistant cefotaxime, imipenem, and amoxicillin-clavulanic acid, and ampicillin. Serratia sp. isolates were 100% and 80% sensitive to norfloxacine and amikacine respectively. There was relationship between antibiotic resistance and biofilm production. E. coli, Enterobacter sp., and Citrobacter sp. strains were all OXA-48 producers.Conclusion: The results of the present study demonstrate the emergence of multidrug resistant organisms, the correlation between antibiotic resistance- biofilm formation and OXA-48 production. These results suggest the implementation of antimicrobial resistance survey programm in order to prevent and combat the spread of multidrug resistant organisms in hospital and community in Democratic Republic of Congo.

scholarly journals Study of Biofilm Formation and Antibiotic Resistance Pattern of Bacteria Isolated from Diabetic Foot Ulcers in Hôpital de Référence Saint Joseph, Kinshasa, Democratic Republic of Congo

2021 ◽  
Vol 11 (05) ◽  
pp. 283-295
Author(s):  
Jean-Marie Liesse Iyamba ◽  
Victoire Marie Hermine Ngo Bassom ◽  
Cyprien Mbundu Lukukula ◽  
Joseph Welo Unya ◽  
Benjamin Kodondi Ngbandani ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Diabetic Foot ◽  
Biofilm Formation ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Foot Ulcers ◽  
Resistance Pattern ◽  
Diabetic Foot Ulcers ◽  
Republic Of Congo ◽  
Antibiotic Resistance Pattern

A battle against antibiotic resistance

Nature ◽  
2019 ◽  
Author(s):  
Virginia Gewin
Keyword(s):  
Antibiotic Resistance
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