To improve the efficiency and accuracy of relay setting calculation of power system, this paper proposed and developed a schematized and open-ended software platform in integrative relay setting. Through the advanced development of the Visio software, the graphical input of the target system topology and component parameters are made possible. The platform can automatically generate PSCAD simulation model according to the topology information and device parameters through an interface program to PSCAD, and use this power system simulation software to improve the accuracy of short-circuit current calculation. With the help of the Bookmark mechanism of WORD software, the platform provides a setting template with general protection components, which forms the basis to realize the open-ended platform. The platform also uses the API interface provided by WORD software to automatically generate the final relay protection setting report document according to the results of short-circuit current calculation and the selected protection setting components. This paper gives in detail the overall framework of the proposed platform, as well as the principle and practice of all the above parts. Moreover, the validity and practicality in improving the automation degree of the relay setting of power plant are shown through practical applications.