scholarly journals Isoniazid Preventive Therapy Associated Hepatotoxicity among Children Living with HIV: Descriptive Case Series at Mildmay Uganda HIV/AIDS Clinic, Uganda

2015 ◽  
Vol 06 (06) ◽  
pp. 384-391
Author(s):  
Lawrence Nsobya ◽  
Henry Nsobya ◽  
Jane Nakaweesi ◽  
Esther Kawuma ◽  
Mary Odiit ◽  
...  
2015 ◽  
Vol 68 ◽  
pp. S297-S305 ◽  
Author(s):  
Melissa A. Briggs ◽  
Courtney Emerson ◽  
Surbhi Modi ◽  
Nicholas Kenji Taylor ◽  
Anand Date

Author(s):  
Christopher Dye

This chapter examines the dual epidemic of tuberculosis and HIV/AIDS. There have been some major successes in the control of both HIV/AIDS and TB. The discovery and widespread use of antiretroviral therapy (ART) is among the greatest advances in public health during the past thirty years. The rise of TB cases in Africa and elsewhere and on the discovery and implementation of control measures raise a series of questions about the population biology of TB linked to HIV/AIDS. The chapter first provides an overview of HIV infection as a risk factor for TB before discussing the global epidemiology of TB linked to HIV/AIDS. It then describes the anatomy of a TB-HIV epidemic, along with TB control in the presence of HIV. In particular, it considers ART and isoniazid preventive therapy. The chapter concludes with the argument that the DOTS strategy is necessary but not sufficient for TB–HIV control.


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