A Novel Targeting Drug Delivery System Based on Self-Assembled Peptide Hydrogel

A novel RNA-triple-helix hydrogel for treatment of triple negative breast cancers (TNBCs) by incorporating RNA-triple-helix and siRNA duplexes of CXCR4 into the same RNA nanoparticles was developed, without the synthetic polycationic reagents.

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Self-assembled pH-responsive supramolecular hydrogel for hydrophobic drug delivery

RSC Advances ◽

10.1039/c8ra06064a ◽

2018 ◽

Vol 8 (55) ◽

pp. 31581-31587 ◽

Cited By ~ 6

Author(s):

Lin Wang ◽

Xuefeng Shi ◽

Jian Zhang ◽

Yuejun Zhu ◽

Jinben Wang

Keyword(s):

Drug Delivery ◽

Cancer Cells ◽

Drug Delivery System ◽

Delivery System ◽

Hydrophobic Drug ◽

Ph Responsive ◽

Supramolecular Hydrogel ◽

Self Assembled

Supramolecular hydrogel, AGC16/NTS, was used to encapsulate hydrophobic drug curcumin (Cur), constructing a pH-responsive drug delivery system; the uptake of released Cur by cancer cells also occurred.

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Supramolecular self-assembled drug delivery system (SADDs) of vancomycin and tocopherol succinate as an antibacterial agent: in vitro, in silico and in vivo evaluations

Pharmaceutical Development and Technology ◽

10.1080/10837450.2020.1797786 ◽

2020 ◽

Vol 25 (9) ◽

pp. 1090-1108

Author(s):

Mohammed Salih ◽

Calvin A. Omolo ◽

Nikita Devnarain ◽

Ahmed A. Elrashedy ◽

Chunderika Mocktar ◽

...

Keyword(s):

Drug Delivery ◽

Drug Delivery System ◽

Delivery System ◽

In Silico ◽

Antibacterial Agent ◽

Self Assembled

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Dual response to pH and chiral microenvironments for the release of a flurbiprofen-loaded chiral self-assembled mesoporous silica drug delivery system

Colloids and Surfaces B Biointerfaces ◽

10.1016/j.colsurfb.2020.111501 ◽

2021 ◽

Vol 199 ◽

pp. 111501

Author(s):

Lulu Wu ◽

Kaijun Gou ◽

Xianmou Guo ◽

Yingyu Guo ◽

Muyun Chen ◽

...

Keyword(s):

Drug Delivery ◽

Mesoporous Silica ◽

Drug Delivery System ◽

Delivery System ◽

Dual Response ◽

Self Assembled

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Highly uniform self-assembled microspheres from single macromolecule self-recognition for enhanced cancer immunotherapy

Chemical Communications ◽

10.1039/d0cc04255b ◽

2020 ◽

Vol 56 (64) ◽

pp. 9190-9193

Author(s):

Xin Shen ◽

Zhenxia Zhou ◽

Dongmei Qi ◽

Yanchao Li ◽

Zhiying Zeng ◽

...

Keyword(s):

Drug Delivery ◽

Cancer Immunotherapy ◽

Drug Delivery System ◽

Delivery System ◽

Local Drug Delivery ◽

Self Recognition ◽

Self Assembled ◽

Local Drug Delivery System ◽

Highly Uniform ◽

Single Macromolecule

Self-assembled highly uniform microspheres has been developed as a local drug delivery system for effective synergistic immunotherapy.

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Pharmaceutically Active Ionic Liquid Self-Assembled Vesicles for the Application as an Efficient Drug Delivery System

ChemPhysChem ◽

10.1002/cphc.201300509 ◽

2013 ◽

Vol 14 (15) ◽

pp. 3454-3457 ◽

Cited By ~ 22

Author(s):

Longlong Zhang ◽

Jing Liu ◽

Tingting Tian ◽

Ya Gao ◽

Xiaoqing Ji ◽

...

Keyword(s):

Drug Delivery ◽

Ionic Liquid ◽

Drug Delivery System ◽

Delivery System ◽

Self Assembled

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Development of Core-Crosslinked Micelles for Drug Delivery System

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.486.449 ◽

2012 ◽

Vol 486 ◽

pp. 449-454 ◽

Cited By ~ 1

Author(s):

Yue Zhao ◽

Ming Tao Liang ◽

Yoseop Kim ◽

Xin Tan ◽

Ling Zhang ◽

...

Keyword(s):

Drug Delivery ◽

Drug Delivery System ◽

Delivery System ◽

Raft Polymerization ◽

Poly Ethylene Glycol ◽

Reversible Addition ◽

Self Assembled ◽

Poly Ethylene ◽

Crosslinked Micelles ◽

Glycol Methyl Ether

A polymer drug delivery system was developed using crosslinked self-assembled micelles, which form stable coreshell particles. The block copolymer, composed of poly [poly (ethylene glycol) methyl ether methacrylat-block-[poly (methyl methacrylate-p-nitrophenyl acrylate)] [P(PEGMEMA)-b-P(MMA-NPA)], was synthesized via reversible addition fragmentation chain transfer (RAFT) polymerization. The self-assembled micelles were stabilized by core crosslinking through the reaction of p-nitrophenyl acrylate with 1,8-octandiamine forming stable coreshell particles.

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