A Study on The Left Ventricular Diastolic Dysfunction in Ischemic Heart Disease: Influence of Left Ventricular Diastolic Dysfunction on Left Atrium

1995 ◽  
Vol 3 (2) ◽  
pp. 121
Author(s):  
Joon Woo Kim ◽  
Joo Han Kim ◽  
Sung Hee Kim ◽  
Jay Young Rhew ◽  
Youl Bae ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Diastolic Dysfunction ◽  
Left Atrium ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Ventricular Diastolic Dysfunction

scholarly journals Left ventricular diastolic dysfunction in women with nonobstructive ischemic heart disease: insights from magnetic resonance imaging and spectroscopy

2017 ◽  
Vol 313 (4) ◽  
pp. R322-R329 ◽  
Author(s):  
Michael D. Nelson
Keyword(s):  
Heart Failure ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Diastolic Dysfunction ◽  
Obstructive Coronary Artery Disease ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Major Adverse Cardiovascular Events ◽  
Ventricular Diastolic Dysfunction

Ischemic heart disease, in the absence of obstructive coronary artery disease, is prevalent in women and constitutes a major risk factor for developing major adverse cardiovascular events, including myocardial infarction, stroke, and heart failure. For decades, diagnosis was considered benign and often minimized; however, it is now known that this etiology carries much risk and is a significant burden to the health care system. This review summarizes the current state of knowledge on nonobstructive ischemic heart disease (NOIHD), the association between NOIHD and left ventricular diastolic dysfunction, potential links between NOIHD and the development of heart failure with preserved ejection fraction (HFpEF), and therapeutic options and knowledge gaps for patients living with NOIHD.

scholarly journals Left ventricular diastolic dysfunction in primary hypertension and ischemic heart disease-evaluation by doppler echocardiography

2021 ◽  
Vol 8 (6) ◽  
pp. 770
Author(s):  
Rahul Kumar ◽  
Sanjeev Diwakar ◽  
Srinivas .
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Diastolic Dysfunction ◽  
Diastolic Function ◽  
Doppler Echocardiography ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Filling Fraction ◽  
Ventricular Diastolic Dysfunction

Background: Congestive heart failure caused by a predominant abnormality in diastolic function is both common and causes significant morbidity and mortality. The objective of the study was to evaluate application of doppler echocardiography in determining left ventricular diastolic dysfunction in ischemic heart disease and essential hypertension.Methods: Present study is based on analysis of 75 patients of hypertension and 60 patients of IHD (UA, AMI, IMI) admitted to Bapuji and Chigateri general hospital during December 2019 to November 2020. Detailed history and physical examination were done. Every patient was subjected to ECG, CXR, routine investigations and Doppler Echo cardiography.Results: A total of 75 patients of primary hypertension were studied. 37 patients showed diastolic dysfunction with E/A ratio <1, with increased atrial filling fraction. Out of 37 patients, 24 showed LVH and 13 cases did not have LVH. A total of 60 patients of ischemic heart disease were studied. 23 patients showed diastolic dysfunction with E/A ratio <1, with increased atrial filling fraction and prolonged isovolumetric relaxation time.Conclusions: Our findings suggest that myocardial damage in patients with HTN and IHD affects diastolic dysfunction before systolic dysfunction. Doppler echocardiography is a valuable non-invasive method to detect left ventricular diastolic impairment and the intentional assessment of diastolic function is advisable for early detection of LV dysfunction before clinical symptoms appear.

scholarly journals Ischemic heart disease: structural changes of the atria in preinfarction and postinfarction stages

Medicina ◽  
2007 ◽  
Vol 43 (2) ◽  
pp. 125
Author(s):  
Dalia Pangonytė ◽  
Kristina Morkūnaitė ◽  
Elena Stalioraitytė ◽  
Jolanta Zaikauskienė
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Left Atrium ◽  
Structural Changes ◽  
Volume Ratio ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Cardiomyocyte Hypertrophy ◽  
Fibrillar Collagen ◽  
Collagen Network

Objective. The aim of this study was to determine atrial structural remodeling during the development of ischemic heart disease. Material and methods. Quantitative histomorphometric parameters of interstitial collagen network (the percentage volume, perimeter, number of fibers per field and collagen–cardiomyocyte volume ratio) of the atria of 132 autopsied men (mean age 49.7±8.9 years) who had died suddenly (within 6 hours since the onset of terminal heart attack symptoms) due to the first (no postinfarction scars) and repeated (postinfarction scars present) acute “pure” ischemic heart disease were investigated. Results. The main remodeling feature of the wall of the both atria among ischemic heart disease subjects is hypertrophy of cardiomyocytes and hyperplasia of interstitial fibrillar collagen network with the maintenance of the same proportion of contractile myocardium and fibrillar collagen network volume. This proportion in the case of the left atrium persists in both pre- and postinfarction ischemic heart disease groups, while myocardium of the right atrium in preinfarction group subjects is characterized by an excess increase of collagen network as compared to cardiomyocyte hypertrophy, which levels again with that of the control in postinfarction group. Conclusions. At preinfarction stage of ischemic heart disease, remodeling of both atria develops and progresses in the left atrium at postinfarction stage in the relationship with increase of left ventricular dysfunction.

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