scholarly journals Non-invasive real-time assessment of hepatic macrovesicular steatosis in liver donors: Hypothesis, design and proof-of-concept study

2021 ◽  
Vol 13 (10) ◽  
pp. 1208-1214
Author(s):  
Allwyn S Rajamani ◽  
Ashwin Rammohan ◽  
VV Raghavendra Sai ◽  
Mohamed Rela
Keyword(s):  
Real Time ◽  
Proof Of Concept ◽  
Concept Study ◽  
Non Invasive ◽  
Macrovesicular Steatosis ◽  
Time Assessment ◽  
Liver Donors

scholarly journals Evaluation of a micro-spectrometer for the real-time assessment of liver graft with mild-to-moderate macrosteatosis: A proof of concept study

2019 ◽  
Vol 70 (3) ◽  
pp. 423-430 ◽  
Author(s):  
Nicolas Golse ◽  
Cyril Cosse ◽  
Marc-Antoine Allard ◽  
Andrea Laurenzi ◽  
Michele Tedeschi ◽  
...  
Keyword(s):  
Real Time ◽  
Liver Graft ◽  
Proof Of Concept ◽  
The Real ◽  
Concept Study ◽  
Time Assessment

scholarly journals Real-time Neurofeedback Using Functional MRI Could Improve Down-Regulation of Amygdala Activity During Emotional Stimulation: A Proof-of-Concept Study

2013 ◽  
Vol 27 (1) ◽  
pp. 138-148 ◽  
Author(s):  
Annette Beatrix Brühl ◽  
Sigrid Scherpiet ◽  
James Sulzer ◽  
Philipp Stämpfli ◽  
Erich Seifritz ◽  
...  
Keyword(s):  
Real Time ◽  
Functional Mri ◽  
Proof Of Concept ◽  
Down Regulation ◽  
Concept Study ◽  
Amygdala Activity

scholarly journals Classification of complex emotions using EEG and virtual environment: proof of concept and therapeutic implication

2020 ◽  
Author(s):  
Eleonora De Filippi ◽  
Mara Wolter ◽  
Bruno Melo ◽  
Carlos J. Tierra-Criollo ◽  
Tiago Bortolini ◽  
...  
Keyword(s):  
Real Time ◽  
Cross Validation ◽  
Support Vector ◽  
Spectral Features ◽  
Emotional States ◽  
Proof Of Concept ◽  
Neurofeedback Training ◽  
Concept Study ◽  
Complex Emotions

AbstractDuring the last decades, neurofeedback training for emotional self-regulation has received significant attention from both the scientific and clinical communities. However, most studies have focused on broader emotional states such as “negative vs. positive”, primarily due to our poor understanding of the functional anatomy of more complex emotions at the electrophysiological level. Our proof-of-concept study aims at investigating the feasibility of classifying two complex emotions that have been implicated in mental health, namely tenderness and anguish, using features extracted from the electroencephalogram (EEG) signal in healthy participants. Electrophysiological data were recorded from fourteen participants during a block-designed experiment consisting of emotional self-induction trials combined with a multimodal virtual scenario. For the within-subject classification, the linear Support Vector Machine was trained with two sets of samples: random cross-validation of the sliding windows of all trials; and 2) strategic cross-validation, assigning all the windows of one trial to the same fold. Spectral features, together with the frontal-alpha asymmetry, were extracted using Complex Morlet Wavelet analysis. Classification results with these features showed an accuracy of 79.3% on average when doing random cross-validation, and 73.3% when applying strategic cross-validation. We extracted a second set of features from the amplitude time-series correlation analysis, which significantly enhanced random cross-validation accuracy while showing similar performance to spectral features when doing strategic cross-validation. These results suggest that complex emotions show distinct electrophysiological correlates, which paves the way for future EEG-based, real-time neurofeedback training of complex emotional states.Significance statementThere is still little understanding about the correlates of high-order emotions (i.e., anguish and tenderness) in the physiological signals recorded with the EEG. Most studies have investigated emotions using functional magnetic resonance imaging (fMRI), including the real-time application in neurofeedback training. However, concerning the therapeutic application, EEG is a more suitable tool with regards to costs and practicability. Therefore, our proof-of-concept study aims at establishing a method for classifying complex emotions that can be later used for EEG-based neurofeedback on emotion regulation. We recorded EEG signals during a multimodal, near-immersive emotion-elicitation experiment. Results demonstrate that intraindividual classification of discrete emotions with features extracted from the EEG is feasible and may be implemented in real-time to enable neurofeedback.

Non-invasive diagnosis of non-alcoholic steatohepatitis and fibrosis with the use of omics and supervised learning: A proof of concept study

Metabolism ◽  
2019 ◽  
Vol 101 ◽  
pp. 154005 ◽  
Author(s):  
Nikolaos Perakakis ◽  
Stergios A. Polyzos ◽  
Alireza Yazdani ◽  
Aleix Sala-Vila ◽  
Jannis Kountouras ◽  
...  
Keyword(s):  
Supervised Learning ◽  
Proof Of Concept ◽  
Concept Study ◽  
Non Invasive ◽  
Alcoholic Steatohepatitis

Non-invasive optical method for real-time assessment of intracorneal riboflavin concentration and efficacy of corneal cross-linking

2018 ◽  
Vol 11 (7) ◽  
pp. e201800028 ◽  
Author(s):  
Giuseppe Lombardo ◽  
Valentina Villari ◽  
Norberto L. Micali ◽  
Nancy Leone ◽  
Cristina Labate ◽  
...  
Keyword(s):  
Real Time ◽  
Optical Method ◽  
Cross Linking ◽  
Non Invasive ◽  
Time Assessment

scholarly journals Non-Invasive Venous waveform Analysis (NIVA) for volume assessment during complex cranial vault reconstruction: A proof-of-concept study in children

PLoS ONE ◽  
2020 ◽  
Vol 15 (7) ◽  
pp. e0235933 ◽  
Author(s):  
Jenna H. Sobey ◽  
Srijaya K. Reddy ◽  
Kyle M. Hocking ◽  
Monica E. Polcz ◽  
Christy M. Guth ◽  
...  
Keyword(s):  
Cranial Vault ◽  
Waveform Analysis ◽  
Proof Of Concept ◽  
Concept Study ◽  
Non Invasive ◽  
Volume Assessment

scholarly journals Non-Invasive Estimation of Intracranial Pressure by Diffuse Optics: A Proof-of-Concept Study

2020 ◽  
Vol 37 (23) ◽  
pp. 2569-2579
Author(s):  
Jonas B. Fischer ◽  
Ameer Ghouse ◽  
Susanna Tagliabue ◽  
Federica Maruccia ◽  
Anna Rey-Perez ◽  
...  
Keyword(s):  
Intracranial Pressure ◽  
Proof Of Concept ◽  
Diffuse Optics ◽  
Concept Study ◽  
Non Invasive
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