Absorption and metabolism of Chuanxiong Rhizoma decoction with multi-component sequential metabolism method

2019 ◽  
Vol 2019 (4) ◽  
Author(s):  
Anthony P. Davenport ◽  
Amy E. Monaghan

Nomenclature for the chemerin receptors is presented as recommended by NC-IUPHAR [14, 41]). The chemoattractant protein and adipokine, chemerin, has been shown to be the endogenous ligand for both chemerin family receptors. Chemerin1 was the founding family member, and when GPR1 was de-orphanised it was re-named Chermerin2 [41]. Chemerin1 is also activated by the lipid-derived, anti-inflammatory ligand resolvin E1 (RvE1), which is formed via the sequential metabolism of EPA by aspirin-modified cyclooxygenase and lipoxygenase [2, 3]. In addition, two GPCRs for resolvin D1 (RvD1) have been identified: FPR2/ALX, the lipoxin A4 receptor, and GPR32, an orphan receptor [43].


2011 ◽  
Vol 41 (7) ◽  
pp. 492-502 ◽  
Author(s):  
Bradley J. Stevenson ◽  
Jaclyn Bibby ◽  
Patricia Pignatelli ◽  
Sant Muangnoicharoen ◽  
Paul M. O’Neill ◽  
...  

2015 ◽  
Vol 30 (6) ◽  
pp. 902-912 ◽  
Author(s):  
Lei Zhang ◽  
Haiyu Zhao ◽  
Yang Liu ◽  
Honghuan Dong ◽  
Beiran Lv ◽  
...  

2002 ◽  
Vol 30 (12) ◽  
pp. 1436-1440 ◽  
Author(s):  
Hiroshi Hasegawa ◽  
Takehisa Matsukawa ◽  
Yoshihiko Shinohara ◽  
Takao Hashimoto

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