MATHEMATICAL MODELING OF THE IMPACT OF MALARIA VACCINES ON THE CLINICAL EPIDEMIOLOGY AND NATURAL HISTORY OF PLASMODIUM FALCIPARUM MALARIA: OVERVIEW

2006 ◽  
Vol 75 (2_suppl) ◽  
pp. 1-10 ◽  
Author(s):  
THOMAS SMITH ◽  
GUY HUTTON ◽  
LOUIS MOLINEAUX ◽  
GERRY F. KILLEEN ◽  
FABRIZIO TEDIOSI ◽  
...  
Nature ◽  
2015 ◽  
Vol 528 (7580) ◽  
pp. S94-S101 ◽  
Author(s):  
Hannah C. Slater ◽  
Amanda Ross ◽  
André Lin Ouédraogo ◽  
Lisa J. White ◽  
Chea Nguon ◽  
...  

2012 ◽  
Vol 29 (11) ◽  
pp. 3427-3439 ◽  
Author(s):  
Hsiao-Han Chang ◽  
Daniel J. Park ◽  
Kevin J. Galinsky ◽  
Stephen F. Schaffner ◽  
Daouda Ndiaye ◽  
...  

2003 ◽  
Vol 25 (6) ◽  
pp. 15-18 ◽  
Author(s):  
Andrew Prentice ◽  
Conor Doherty ◽  
Joann McDermid ◽  
Sarah Atkinson ◽  
Sharon Cox

Young children in rural Gambia face constant exposure to gastrointestinal and respiratory infections and, during the rainy season (July–November), suffer recurrent bouts of Plasmodium falciparum malaria. Within living memory, these conditions led to more than half of the children dying before their fifth birthday, providing a graphic demonstration of the impact that infectious diseases have had on our natural selection. Fortunately, these horrific statistics have been decreased greatly by improved medical care, especially through vaccination and anti-malarial therapies, but conditions such as these have inevitably left a powerful imprint on man's genetic make-up.


2015 ◽  
Vol 93 (6) ◽  
pp. 1254-1259 ◽  
Author(s):  
Andrew S. Walker ◽  
José Lourenço ◽  
Adrian V. S. Hill ◽  
Sunetra Gupta

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