Risk Factors Associated with Life-threatening Rickettsial Infections

2008 ◽  
Vol 78 (6) ◽  
pp. 973-978 ◽  
Author(s):  
Nelson Lee ◽  
Owen Tak Yin Tsang ◽  
Grace Lui ◽  
Sik To Lai ◽  
Bonnie Wong ◽  
...  
Blood ◽  
2012 ◽  
Vol 120 (3) ◽  
pp. 528-537 ◽  
Author(s):  
Karina Yazdanbakhsh ◽  
Russell E. Ware ◽  
France Noizat-Pirenne

Abstract Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious complications for the patient including life-threatening delayed hemolytic transfusion reactions and difficulty in finding compatible units, which can cause transfusion delays. In this review, we discuss the risk factors associated with alloimmunization with emphasis on possible mechanisms that can trigger delayed hemolytic transfusion reactions in sickle cell disease, and we describe the challenges in transfusion management of these patients, including opportunities and emerging approaches for minimizing this life-threatening complication.


2012 ◽  
Vol 97 (Suppl 2) ◽  
pp. A245-A245
Author(s):  
Z. Badiei ◽  
M. Alami ◽  
M. Khalesi ◽  
H. Farhangi ◽  
A. Banihashem ◽  
...  

2021 ◽  
Vol 2 (5) ◽  
pp. 159-162
Author(s):  
Chris Kim ◽  
Andrea Hladik

Introduction: A well-documented complication of administering tissue plasminogen activator (tPA) in stroke patients is acute intracranial bleeding. A lesser known but still significant complication is angioedema secondary to tPA administration, which can develop in certain individuals with risk factors such as angiotensin converting enzyme (ACE) inhibitor use and location of the stroke. Knowing the potential for this life-threatening complication and being prepared for its proper management is vital for emergency physicians. Case Report: We report a 53-year-old Black female who presented to the emergency department with sudden onset of slurred speech and a facial droop. She was found to have an acute ischemic stroke and tPA was administered. She subsequently developed angioedema. Retrospectively, the patient was found to have risk factors that are thought to predispose patients to tPA-induced angioedema. Conclusion: Risk factors associated with angioedema secondary to tPA administration have been documented in patients taking ACE inhibitors, as well as patients who develop strokes in the frontal lobe. While many cases may be mild, some patients may develop life-threatening angioedema. Although this complication does not necessarily contraindicate tPA use, it is prudent for the emergency physician to be vigilant for its development, prepared for its treatment, and to be diligent in assessing the need for control of the patient’s airway.


2011 ◽  
Vol 33 (1) ◽  
pp. e9-e12 ◽  
Author(s):  
Zahra Badiei ◽  
Maryam Khalesi ◽  
Mohammad Hasan Alami ◽  
Hamid Reza Kianifar ◽  
Abdollah Banihashem ◽  
...  

Author(s):  
Cory M. Furse ◽  
Matthew D. McEvoy

Laryngospasm is one of the most vexing problems in anesthesia and perioperative care. The onset of which carries the risk of oxygen desaturation, bradycardia, aspiration, and cardiac arrest. In this chapter, the mechanisms involved in producing laryngospasm are covered in detail, and an anatomical review of both sensory and motor innervation is included. Risk factors associated with the development of laryngospasm, including those specific to the patient, the type of surgery, and/or the anesthesia techniques are discussed. Proper patient assessment and prompt treatment for this life-threatening emergency are essential skills needed for safe patient care in the peri-operative arena.


2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Ubong Akpan ◽  
Chinyere Akpanika ◽  
Victor Nwagbara ◽  
Udeme Asibong ◽  
Saturday Etuk

Uterine rupture is a life threatening obstetric emergency and is associated with high maternal and perinatal mortality. There are some risk factors associated with uterine rupture which may include: prolonged obstructed labour, previous scarred uterus, grand-multiparity, macrosomic baby, abnormal lie, instrumental delivery, induction of labour, oxytocin stimulation and excessive uterine manipulation. Its modes of presentation have been widely reported. Here, we present a case with an unusual mode of presentation where about two-third of the small intestines protruded through the vagina following some manipulations by an unskilled birth attendant. This highlights the fact that when uterine rupture is suspected, the cord-like structure protruding per vaginum may not always be umbilical cord.


Author(s):  
Angharad Walters ◽  
Ronan Lyons ◽  
Damon Berridge

ABSTRACTObjectivesCritical care provides specialist treatment for patients with life-threatening illnesses and injuries. Outcomes data are fundamental to identify where resources need to be focused to provide safer care; we can determine long term survival after critical care and identify the risk factors of mortality by linking the critical care data with a mortality register, thereby building on previous survival reporting which is constrained to mortality within the admission. The objective is to identify the factors that increase the risk of mortality following discharge from critical care.ApproachAnonymised critical care data reported from 1st April 2006 are held within the Secure Anonymised Information Linkage (SAIL) databank and will be linked with ONS mortality data, inpatients data and the Welsh Demographic Service dataset. Details of patient care during the critical care admission such as duration of level 2/3 support, the organs supported and discharge details such as the time of day, along with patient demographics such as age, sex and socioeconomic factors are available for analysis. Adult Welsh patients alive at the discharge date and with a discharge date from critical care on or before 31.12.2013 will be followed up until 31.12.2014, outward migration or death. ResultsSurvival analysis techniques will be used to determine the risk of death at certain time points after discharge from critical care and to identify the risk factors associated with mortality. ConclusionDetermining the factors associated with mortality will allow patients at highest risk of death to be identified. If these risk factors are modifiable, then preventive interventions can be introduced to reduce the number of avoidable deaths.


2014 ◽  
Author(s):  
Ariel M. Barber ◽  
Alexandra Crouch ◽  
Stephen Campbell

1992 ◽  
Vol 68 (03) ◽  
pp. 261-263 ◽  
Author(s):  
A K Banerjee ◽  
J Pearson ◽  
E L Gilliland ◽  
D Goss ◽  
J D Lewis ◽  
...  

SummaryA total of 333 patients with stable intermittent claudication at recruitment were followed up for 6 years to determine risk factors associated with subsequent mortality. Cardiovascular diseases were the underlying cause of death in 78% of the 114 patients who died. The strongest independent predictor of death during the follow-up period was the plasma fibrinogen level, an increase of 1 g/l being associated with a nearly two-fold increase in the probability of death within the next 6 years. Age, low ankle/brachial pressure index and a past history of myocardial infarction also increased the probability of death during the study period. The plasma fibrinogen level is a valuable index of those patients with stable intermittent claudication at high risk of early mortality. The results also provide further evidence for the involvement of fibrinogen in the pathogenesis of arterial disease.


2013 ◽  
Author(s):  
Giovanni Corona ◽  
Giulia Rastrelli ◽  
Emmanuele Jannini ◽  
Linda Vignozzi ◽  
Edoardo Mannucci ◽  
...  

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