The increasing number of thin malignant melanomas (≤1 mm in thickness) asks for better acknowledgement of prognostic factors of the disease; this is the purpose of this research [1, 2]. The plastic surgery unit of the hospital Spedali Civili of Brescia has collected over 450 cases of thin malignant melanoma over a period of 20 years, from 1990 to 2010, in order to obtain as much information as possible about prognostic factors. These data have been analyzed using the Chi-squared test to reveal the influence on prognosis of each one of the 16 prognostic factors that have been chosen for this study; both the development of a metastasis and the death of the patient were considered for outcome study. The univariate analysis describes the presence of the phase of vertical growth as the only prognostic factor statistically significant for both metastasis development and death.
Primary Sinonasal Malignant Melanoma: Effect of Clinical and Histopathologic Prognostic Factors on Survival
