Comparison of Cutting Diathermy and Scalpel in Terms of Delay in Wound Healing and Scar Appearance in Skin Incision: A Prospective Observational Study

Background: The study was conducted to determine the diagnostic accuracy of ankle branchial pressure index (ABPI) in predicting major amputation and duration of wound healing in diabetic foot ulcers.Methods: 105 participants (30-85 years) admitted in general surgery inpatient with diabetic foot ulcers during 18 months were enrolled in the present prospective observational study. Institutional ethics committee approved the study and written informed consent was obtained from all study participants. Data was analyzed using R and the tests of significance were chi square test and ANOVA. Area under curve (AUC) of receiver operator characteristic (ROC) was used to describe the diagnostic accuracy of ABPI. P<0.05 was considered statistically significant.Results: The mean ABPI of study participants was 0.7 with 23.8% participants having normal ABPI. Lower ABPI was associated with longer duration of ulcer healing (p=0.003). All participants with ABPI <0.3 required more than 120 days for wound healing (p<0.001) and required above knee amputation (p<0.001). AUC ROC of ABPI and major amputation is 0.987 with 92.9% sensitivity and 98.9% specificity. Significantly higher proportion of participants with ABPI ≤0.48 underwent major amputation. The AUC of ROC of ABPI on duration of wound healing was 0.953 with 84.9% sensitivity and 98.1% specificity. Conclusions: ABPI can be used as a routine tool in all patients with diabetic foot ulcers for screening peripheral arterial disease so that the decision for amputation can be made early during diabetic foot ulcers.

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Accuracy, Precision, and Trending Ability of Electrical Cardiometry Cardiac Index versus Continuous Pulmonary Artery Thermodilution Method: A Prospective, Observational Study

BioMed Research International ◽

10.1155/2017/2635151 ◽

2017 ◽

Vol 2017 ◽

pp. 1-8 ◽

Cited By ~ 3

Author(s):

P. B. W. Cox ◽

A. M. den Ouden ◽

M. Theunissen ◽

L. J. Montenij ◽

A. G. H. Kessels ◽

...

Keyword(s):

Cardiac Index ◽

Observational Study ◽

Pulmonary Artery ◽

Prospective Observational Study ◽

Skin Incision ◽

Percentage Error ◽

Quadrant Analysis ◽

Polar Plot ◽

Electrical Cardiometry ◽

Trending Ability

Introduction. Evaluation of accuracy, precision, and trending ability of cardiac index (CI) measurements using the Aesculon™ bioimpedance electrical cardiometry (Aesc) compared to the continuous pulmonary artery thermodilution catheter (PAC) technique before, during, and after cardiac surgery. Methods. A prospective observational study with fifty patients with ASA 3-4. At six time points (T), measurements of CI simultaneously by continuous cardiac output pulmonary thermodilution and thoracic bioimpedance and standard hemodynamics were performed. Analysis was performed using Bland-Altman, four-quadrant plot, and polar plot methodology. Results. CI obtained with pulmonary artery thermodilution and thoracic bioimpedance ranged from 1.00 to 6.75 L min−1 and 0.93 to 7.25 L min−1, respectively. Bland-Altman analysis showed a bias between CIBIO and CIPAC of 0.52 liters min−1 m−2, with LOA of [−2.2; 1.1] liters min−1 m−2. Percentage error between the two techniques was above 30% at every time point. Polar plot methodology and 4-quadrant analysis showed poor trending ability. Skin incision had no effect on the results. Conclusion. CI obtained by continuous PAC and CI obtained by Aesculon bioimpedance are not interchangeable in cardiac surgical patients. No effects of skin incision were found. International clinical trial registration number is ISRCTN26732484.

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Prospective observational study comparing burn surgeons’ estimations of wound healing after skin grafting to photo-assisted methods

Burns ◽

10.1016/j.burns.2019.05.013 ◽

2019 ◽

Vol 45 (7) ◽

pp. 1562-1570 ◽

Cited By ~ 1

Author(s):

K.S. Koetsier ◽

J.N. Wong ◽

L.A. Muffley ◽

G.J. Carrougher ◽

T.N. Pham ◽

...

Keyword(s):

Wound Healing ◽

Observational Study ◽

Prospective Observational Study ◽

Skin Grafting

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Single Dose Prophylactic Antibiotic in Caesarean Delivery and its Effect on Maternal Infectious Morbidity: A Prospective Observational Study

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2020/45474.13988 ◽

2020 ◽

Author(s):

Shreedevi Somashekhar Kori ◽

Aruna Mallangouda Biradar ◽

Dayanand Biradar ◽

Subhash Mudanur ◽

Neelamma Patil ◽

...

Keyword(s):

Single Dose ◽

Observational Study ◽

Caesarean Delivery ◽

Prospective Observational Study ◽

Skin Incision ◽

Research Centre ◽

Wound Infections ◽

Cord Clamping ◽

Group A ◽

Group B

Introduction: Caesarean delivery is the most common surgery performed in obstetrics. Antibiotics have revolutionised the surgical practise in this era. But multidrug resistance is a challenging issue in day to day practise. So, antibiotics have to be administered judiciously at the appropriate time with respect to surgery. Aim: To determine whether the administration of single dose injection ceftriaxone 1 gm intravenously prior to skin incision was superior to administration at the time of cord clamping for prevention of post-caesarean maternal infection. Materials and Methods: A prospective observational study was conducted in BLDE (DU) Shri BM Patil Medical College and Research Centre, Vijayapura, Karnataka, India. Patients undergoing caesarean sections for singleton term pregnancies both elective and emergency with intact membranes were included in study during one-year period. Alternatively, group A received 1 gm injection ceftriaxone intravenously 60 minutes before skin incision and group B received at the time of cord clamping during surgery. Chi-square (χ2) test was used for association between two categorical variables. Results: Incidence of obstetric complications such as nausea (0.5% vs 0.0%) and wound infections (6.6% vs 4.1%) were more in patients who received a single dose of ceftriaxone at cord clamping than patients receiving the same antibiotic, preoperatively whereas, incidence of postoperative fever was more in group A (4.1%) than group B (3.3%) which was although not significant but is an important finding in this study. Conclusion: Administration of single dose antibiotic either preoperatively or at the time of cord clamping was not statistically significant in reducing the incidence of wound infections.

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