scholarly journals Combining non-contrast enhanced magnetic resonance thoracic ductography with vascular contrast-enhanced computed tomography to identify the canine thoracic duct

2020 ◽  
Vol 10 (1) ◽  
pp. 68-73
Author(s):  
Kenji Kutara ◽  
Teppei Kanda ◽  
Noritaka Maeta ◽  
Yohei Mochizuki ◽  
Fumiko Ono ◽  
...  

Background: In humans, visualization of the thoracic duct by magnetic resonance imaging (MRI) has been attempted, and recent advances have enabled clinicians to visualize the thoracic duct configuration in a less invasive manner. Moreover, MRI does not require contrast media, and it enables visualization of morphological details of the thoracic structures. In veterinary practice, the thoracic duct has not been visualized three dimensionally in MRI.Aim: This study aimed to assess the performance of our magnetic resonance thoracic ductography (MRTD) technique to visualize the thoracic duct and the surrounding 3D anatomical structures by combining MRTD and vascular contrastenhanced thoracic computed tomography (CT) images in dogs.Methods: Five adult male beagle dogs (11.4–12.8 kg) were included in this study. Sagittal and transverse T2-weighted images were scanned in MRI. Scanning in MRTD used a single-shot fast spin echo sequence with a respiratory gate. CT was performed after the intravenous injection of contrast medium. All MRTD and CT images were merged using a workstation.Results: The thoracic ducts were identified in MRTD images of all dogs, and the surrounding anatomical structures were located with the aid of contrast-enhanced thoracic CT. In all dogs, the thoracic ducts coursed along the rightdorsal side of the aorta, cranially from the L2 level. Thereafter, these bent to the left side at the aortic arch and curved at the left external jugular vein angle. A comparison of the number of thoracic ducts at each vertebra between transverse T2WI and MRTD did not reveal any significant differences for all vertebrae.Conclusion: The results from our study suggest that MRTD using the single-shot fast spin echo sequence could be a useful tool for visualization of the thoracic duct. Furthermore, the image merged from MRTD and vascular-enhanced images provided detailed anatomical annotation of the thorax. The MRTD protocol described in this study is safe and easily adaptable, without the need for contrast medium injection into the lymph system. In addition, the images fused from MRTD and vascular contrast-enhanced CT image of the thorax could provide detailed anatomical annotations for preoperative planning. Keywords: Computed tomography, Dog, Magnetic resonance imaging, Thoracic duct, Thoracic ductography.

1998 ◽  
Vol 39 (3) ◽  
pp. 435
Author(s):  
Sung Ho Cha ◽  
Jeong Jin Seo ◽  
Hee Yeon Oh ◽  
Jong Hoon Yoon ◽  
Gwang Woo Jeong ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Stefano Palmucci ◽  
Federica Roccasalva ◽  
Marina Piccoli ◽  
Giovanni Fuccio Sanzà ◽  
Pietro Valerio Foti ◽  
...  

Since its introduction, MRCP has been improved over the years due to the introduction of several technical advances and innovations. It consists of a noninvasive method for biliary tree representation, based on heavily T2-weighted images. Conventionally, its protocol includes two-dimensional single-shot fast spin-echo images, acquired with thin sections or with multiple thick slabs. In recent years, three-dimensional T2-weighted fast-recovery fast spin-echo images have been added to the conventional protocol, increasing the possibility of biliary anatomy demonstration and leading to a significant benefit over conventional 2D imaging. A significant innovation has been reached with the introduction of hepatobiliary contrasts, represented by gadoxetic acid and gadobenate dimeglumine: they are excreted into the bile canaliculi, allowing the opacification of the biliary tree. Recently, 3D interpolated T1-weighted spoiled gradient echo images have been proposed for the evaluation of the biliary tree, obtaining images after hepatobiliary contrast agent administration. Thus, the acquisition of these excretory phases improves the diagnostic capability of conventional MRCP—based on T2 acquisitions. In this paper, technical features of contrast-enhanced magnetic resonance cholangiography are briefly discussed; main diagnostic tips of hepatobiliary phase are showed, emphasizing the benefit of enhanced cholangiography in comparison with conventional MRCP.


2008 ◽  
Vol 21 (6) ◽  
pp. 795-799
Author(s):  
E. Tedeschi ◽  
C. Iaccarino ◽  
E.M. Covelli ◽  
A. Rapanà ◽  
M.L. Barretta ◽  
...  

A spontaneous CSF fistula of the sphenoid sinus was preoperatively diagnosed in a young woman presenting with massive pneumocephalus and rhinorrhea. Diagnosis was established by MR cisternography using a heavily T2-weighted 3D single-shot FSE sequence with half-Fourier analysis (3D-EXPRESS®), originally developed for imaging the inner ear. While unenhanced CT failed to detect the site of the fistula, MR permitted complete evaluation of the sellar/sphenoid region and tracked the CSF signal down to the nasal cavity.


2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Andreas Müller ◽  
Katrin Hochrath ◽  
Jonas Stroeder ◽  
Kanishka Hittatiya ◽  
Günther Schneider ◽  
...  

Recently, clinical studies demonstrated that magnetic resonance relaxometry with determination of relaxation times T1 andT2⁎may aid in staging and management of liver fibrosis in patients suffering from viral hepatitis and steatohepatitis. In the present study we investigated T1 andT2⁎in different models of liver fibrosis to compare alternate pathophysiologies in their effects on relaxation times and to further develop noninvasive quantification methods of liver fibrosis. MRI was performed with a fast spin echo sequence for measurement of T1 and a multigradient echo sequence for determination ofT2⁎. Toxic liver fibrosis was induced by injections of carbon tetrachloride (1.4 mL CCl4per kg bodyweight and week, for 3 or 6 weeks) in BALB/cJ mice. Chronic sclerosing cholangitis was mimicked using the ATP-binding cassette transporter B4 knockout(Abcb4 -/-)mouse model. Untreated BALB/cJ mice served as controls. To assess hepatic fibrosis, we ascertained collagen contents and fibrosis scores after Sirius red staining. T1 andT2⁎correlate differently to disease severity and etiology of liver fibrosis.T2⁎shows significant decrease correlating with fibrosis in CCl4treated animals, while demonstrating significant increase with disease severity inAbcb4 -/-mice. Measurements of T1 andT2⁎may therefore facilitate discrimination between different stages and causes of liver fibrosis.


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