scholarly journals Iron deficiency anemia and associated factors among pregnant women in a tertiary care hospital, in Sargodha District, Pakistan

2021 ◽  
Vol 18 (10) ◽  
pp. 2183-2187
Author(s):  
Sumbul Qamar ◽  
Saira Azhar ◽  
Saadoon Mazhar ◽  
Khush Bakht ◽  
Ghulam Murtaza
Keyword(s):  
Risk Factors ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Tertiary Care Hospital ◽  
Binding Capacity ◽  
Tertiary Care ◽  
Deficiency Anemia ◽  
Care Hospital ◽  
Total Blood

Purpose: To evaluate iron deficiency anemia and other concomitant risk factors among pregnant women in a tertiary care hospital in Sargodha District of Pakistan. Methods: An observational cross-sectional study on pregnant women over a six-month period from December 2016, was conducted in the gynaecology and obstetrics department of the District Headquarters Hospital, Sargodha, Pakistan. All women with renal failure, heart disease and surgical history were excluded from the study, while all pregnant women visiting the out-patient department (OPD) were included in the investigation. Blood sampling and analysis were performed, following standard laboratory operating procedures to determine the haemoglobin (Hb) levels of the patients. Results: Fifty pregnant women were enrolled in this study. They had a mean age of 27.85 ± 4.99 years with a range of 20 – 46 years. Almost half, i.e., 26 (52 %), were aged 20 – 30 years; 18 (36 %) 31 – 40 years and six (12 %) > 40 years of age. Regarding occupational status, 45 (90 %) of the respondents were housewives. In total, 86 % of the women were anemic, while the remaining 14 % were non-anemic and had an Hb level slightly > 11 g/dL. Among the anemic women, 13 (26 %) had mild anemia, 33 (66 %) moderate anemia, and 4 (8 %) were severely anemic. Conclusion: Iron deficiency and anemia have major health impacts on pregnant women. Steps should be taken during ante-natal care to monitor Hb levels in pregnant women and apply appropriate remedy where necessary. Other biomarkers and related risk factors such as total iron binding capacity (TIBC) and total blood count (TBC) have previously been found to be linked to anemia

scholarly journals Association of Iron Deficiency Anemia with Febrile Seizure in Children in a Tertiary Care Hospital

2021 ◽  
Vol 19 (1) ◽  
pp. 66-70
Author(s):  
Brajesh Raj Chaudhary ◽  
Kalpana Karmacharya Malla ◽  
Binod Gaire
Keyword(s):  
Risk Factors ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Febrile Seizure ◽  
Binding Capacity ◽  
Tertiary Care ◽  
Transferrin Saturation ◽  
Deficiency Anemia ◽  
Seizure Threshold ◽  
Care Hospital

Background: Febrile seizure is the most common cause of seizure in children. Iron deficiency, by lowering seizure threshold, is proposed to be one of the risk factors for febrile seizure. Many studies have been done to determine the association of iron deficiency anemia with febrile seizure but the results are controversial. Hence, the present study was conducted to evaluate the association of iron deficiency anemia with febrile seizure in Nepalese children. Methods: A prospective age and sex matched case control study was performed in 68 cases of febrile seizures and 68 controls of febrile illness without seizure after calculating the sample size. The study was conducted from October 21, 2019 to October 20, 2020 in Pediatric ward and intensive care unit of College of Medical Sciences, Bharatpur, Nepal after obtaining ethical clearance from institutional review committee. Data entry was done in statistical packages for the social science version 20.Results: Mean of haematological parameters (haemoglobin and mean corpuscular volume) as well as mean of serum iron, ferritin and transferrin saturation were significantly less and total iron binding capacity was significantly high in cases as compared to controls (P <0.05). Iron deficiency anemia was significantly associated with cases (59.7%), with odds ratio of 2.5 (95% confidence interval =1.24 – 5.01) as compared to control (40.3%) (P <0.05).Conclusions: Iron deficiency anemia may be considered one of the risk factors for febrile seizure in children. Hence, Children with febrile seizure should be investigated and treated for Iron deficiency anemia.Keywords: Children; febrile seizure; iron deficiency anemia

scholarly journals Role of ferric carboxymaltose in the treatment of postpartum anemia in a tertiary care hospital in Andhra Pradesh

2021 ◽  
Vol 10 (10) ◽  
pp. 3889
Author(s):  
Kirtan Krishna ◽  
Achint Krishna ◽  
Divya Teja G. N.
Keyword(s):  
Iron Deficiency ◽  
Patient Compliance ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Deficiency Anemia ◽  
Ferric Carboxymaltose ◽  
Care Hospital ◽  
Parenteral Iron

Background: Postpartum iron deficiency anemia is common in India as a consequence of postpartum hemorrhage.  Recent studies have evaluated the use of parenteral iron as a better tolerated treatment modality. Compared with oral iron supplements, parenteral iron is associated with a rapid rise in serum ferritin and hemoglobin and improved maternal fatigue scores in the postpartum period.  Parenteral iron may be considered for the treatment of postpartum anemia. The objective of the study was to evaluate the efficacy, safety, and tolerability of intravenous ferric carboxymaltose, in women with postpartum anemia.Methods: A clinical observational study was undertaken in a tertiary care hospital,  50 women within six weeks of delivery with Hb ≥6 gm/dl and ≤10 gm/dl received 1000 mg/week,  over 15 minutes or less, repeated weekly to a calculated replacement dose (maximum 2500 mg) . Hemoglobin and serum ferritin levels were recorded prior to treatment and on day 21 after completion of treatment.Results: Ferric carboxymaltose-treated subjects achieved a hemoglobin greater than 12 gm/dL in a short time period (21 days), achieve a hemoglobin rise of ≥3 gm/dL more quickly, and attain higher serum ferritin levels. It is also associated with better patient compliance, and shorter treatment period. Drug-related adverse events occurred less frequently with ferric carboxymaltose. The only noted disadvantage was that it is more expensive when compared to other iron preperations.Conclusions: Intravenous ferric carboxymaltose was safe and well tolerated with good efficacy and better patient compliance in the treatment of postpartum iron deficiency anemia.

scholarly journals Study of Prevalence, Risk Factors and Hematological Parameters in Children Suffering from Iron Deficiency Anemia in a Tertiary Care Centre in Pokhara

2018 ◽  
Vol 1 (2) ◽  
pp. 79-82
Author(s):  
Amrita Ghimire Paudel ◽  
Kalpana Karmacharya Malla ◽  
Shree Krishna Shrestha ◽  
Suresh Raj Paudel ◽  
Deepak Raj Paudel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Binding Capacity ◽  
Hematological Parameters ◽  
Tertiary Care ◽  
Transferrin Saturation ◽  
Dietary Factors ◽  
Physical Growth ◽  
Deficiency Anemia

Introduction: Iron deficiency anemia (IDA) is the most common anemia worldwide. It adversely affects the physical growth, cognition, behavior and the immune status of infants and children. There are limited number of studies in Nepal analyzing its prevalence, risk factors and diagnosis in pediatric population. Restriction of analgesics intake, increased intake of iron rich food and deworming are important determinants in the disease management. Methods: Hospital based prospective comparative study was conducted in the Department of Pediatrics in Manipal Teaching Hospital from December 2014 to December 2016 enrolling all children aged 6 months to 5 years with anemia. Demographic profile, clinical features and information regarding risk factors were noted along with detailed physical examination. Iron profile was done to confirm diagnosis of IDA. Data was analyzed using SPSS 21. Results: Out of 168 anemic children, 110 (65.45%) children were diagnosed as IDA. Dietary factors, pica and intake of analgesics/antipyretics were major risk factors. Serum iron, serum ferritin, transferrin saturation were low whereas total iron binding capacity was high in IDA. Conclusion: Iron deficiency anemia is a common, preventable and easily treatable disease which has potentially serious consequences if not treated. Non compliance to exclusive breastfeeding in the first 6 months of life, introduction of cow’s/buffalo’s milk in the first year, pica and rampant use of analgesics/antipyretics are major risk factors.  

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