scholarly journals AYURVEDIC MANAGEMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS

2021 ◽  
Vol 9 (12) ◽  
pp. 3158-3162
Author(s):  
Vatsal Dhudashiya ◽  
Radhikaba Zala ◽  
Pooja B.A ◽  
Sangamitra Pattnaik

Systemic Lupus Erythematosus is a systemic autoimmune connective tissue disease. Arthralgia is a common symptom, occurring in 90% of patients, and is often associated with early morning stiffness. Considering symp- tomatology, In Ayurveda classics, it can be compared with amavata1. This is the case report of a female patient aged 19 years suffering from multiple joints pain associated with swelling and tenderness and finger deformities, Diagnosed as Systemic lupus erythematosus (SLE). Visited the Department of Panchakarma, SAMC&H, Banga- lore for the treatment. Virechana karma followed by Shamana Aushadhi was administered. Significant improve- ment in the signs and symptoms was observed clinically. Keywords: Systemic Lupus Erythematosus, SLE, Amavata, Virechana, Shamana Auaushadhi

2016 ◽  
Vol 10 (1) ◽  
pp. 122-128 ◽  
Author(s):  
Emily C. Milam ◽  
Jacobo Futran ◽  
Andrew G. Franks Jr.

Background: Dermatomyositis (DM) is an autoimmune connective tissue disease that primarily targets the muscle, skin, and lungs. Many patients have autoantibodies that correspond to distinct clinical phenotypes. Melanoma differentiation-associated gene 5 (anti-MDA5) antibody, a specific antibody that targets the melanoma differentiation-associated gene 5 (MDA5), has been reported in DM cases and is significant for a distinct cutaneous presentation and rapidly progressive interstitial lung disease. Objective: Herein, we describe a patient with DM with a positive anti-MDA5 antibody and characteristic clinical phenotype, who subsequently developed coexisting systemic lupus erythematosus (SLE). A diagnosis of SLE was supported by his clinical phenotype, positive serologies, hypocomplementemia, and progression to glomerulonephritis and lupus cerebritis, features of which fulfilled the American College of Rheumatology criteria for SLE. Conclusion: DM is known to overlap with other autoimmune diseases, including SLE, and coexistence can lead to a wide variety of clinical presentations. SLE overlapping with anti-MDA5 positive DM may present with distinct clinical features.


2014 ◽  
Vol 20 (12) ◽  
pp. e256-e259
Author(s):  
Po-Hsun Chen ◽  
Jun-Sing Wang ◽  
Jen-I Hwang ◽  
Shih-Yi Lin ◽  
Wayne H.-H. Sheu ◽  
...  

2021 ◽  
Vol 7 (2) ◽  
pp. 5
Author(s):  
Yunia Duana ◽  
Lucia Kris Dinarti ◽  
Dyah Wulan Anggrahini ◽  
Anggoro Budi Hartopo ◽  
Bambang Irawan

One of the causes of pulmonary arterial hypertension (PAH) is connective tissue disease, including systemic lupus erythematosus (SLE). The prevalence of PAH in patients with SLE according to cohort studies varies widely between 0.5% and 43%. In some cases, PAH is the initial manifestation leading to the diagnosis of SLE. However, PAH can develop as a complication in patients who are initially diagnosed with SLE. We report two cases with a different approach to the diagnosis of pulmonary hypertension in SLE patients. These cases emphasize the importance of investigating examination results according to the guidelines to establish the diagnosis of PAH in SLE.


2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Austin Anderson

Systemic Lupus Erythematosus (SLE) is an autoimmune disorder characterized by multiorgan system involvement. Hematologic manifestations are common in SLE and include thrombocytopenia in as many as 50% of patients. Thrombocytosis is much less common in SLE, occurring in less than 5% of patients, and is typically reported in association with autosplenectomy. The following case report describes a 35-year-old female patient who presented for evaluation with extreme thrombocytosis of unclear etiology. The patient was diagnosed with reactive thrombocytosis due to active SLE for which treatment with corticosteroids and plaquenil was provided with subsequent decline in platelet counts. This report highlights the importance of considering SLE in the differential for thrombocytosis despite its classic association with thrombocytopenia.


2019 ◽  
Vol 12 (12) ◽  
pp. e230869
Author(s):  
Satyendra Kumar Sonkar ◽  
Satish Kumar ◽  
Virendra Atam ◽  
Shyam Chand Chaudhary

Digital dry gangrene is commonly seen in cases of connective tissue disease such as systemic sclerosis. In systemic lupus erythematosus (SLE) digital gangrene is rare. As initial manifestation, it is again a rare phenomenon because it occurs late in the course of disease. Here we are reporting the case of a woman who was having extensive cutaneous gangrene of her fingers and toes, as a first and foremost presentation without any other typical signs and symptoms of SLE. Her serology was positive for SLE. The patient was treated conservatively and responded well.


2021 ◽  
Vol 12 ◽  
Author(s):  
Ewa Stelmach ◽  
Jolanta Masiak

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease that leads to a chronic inflammatory process in tissues and organs. The neuropsychiatric systemic lupus erythematosus (NPSLE) is a set of neuropsychiatric symptoms that derive from the central and peripheral nervous system and are observed in the course of SLE.Case Report and Final Diagnostic and Therapeutic Results: A diagnostic and therapeutic process in a patient with the signs and symptoms of SLE and bipolar disorder (BD) has been described. Bipolar disorder has been diagnosed as a primary disorder while SLE as a comorbid disease.Discussion: Common immunological mechanisms in BD and SLE are the reason for difficulties in diagnosing BD with co-occurring SLE. It should be determined whether BD is a primary disorder or a secondary component of a clinical picture of SLE (NPSLE) or whether mood and/or psychotic disorders are the result of steroid therapy in the course of SLE (steroid-induced mood and psychotic disorders, SIMPD).Conclusion and the Patient's Perspective: The presented case report is a unique description of a patient with a primary diagnosis of BD with comorbid SLE.


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