scholarly journals Penatalaksanaan Kanker Payudara pada Kehamilan

2021 ◽  
Vol 35 (2) ◽  
pp. 38-42
Author(s):  
Daniel Sampepajung
Keyword(s):  

Kanker payudara pada kehamilan atau pregnancy-associated breast cancer (PABC) merupakan kanker yang paling sering ditemukan pada wanita hamil. Insiden kanker payudara akan meningkat seiring dengan peningkatan umur. Variasi jenis PABC sama dengan kanker payudara pada wanita yang tidak hamil. Pada umumnya PABC asimptomatis dan lebih dari 90% ditemukan oleh pasien pada saat melakukan pemeriksaan payudara sendiri. Peningkatan ukuran, berat, vaskularisasi, dan densitas payudara selama kehamilan menyebabkan kesulitan dalam mendeteksi massa dalam payudara baik secara klinis maupun dengan mammografi. Keterlambatan diagnosis kanker payudara pada wanita hamil dapat terjadi 1 sampai 3 bulan atau lebih sehingga PABC sering ditemukan pada stadium lebih lanjut. Keterlambatan diagnosis kanker payudara ini dapat disebabkan oleh faktor pasien maupun dokter. Biopsi merupakan baku emas untuk menegakkan diagnosis kanker payudara pada kehamilan. Strategi penanganan PABC memerlukan pertimbangan dampaknya terhadap fetus dan kehamilan itu sendiri. Penanganan dilakukan secara multidisiplin dan operasi merupakan pilihan utama untuk PABC. Indikasi kemoterapi untuk PABC sama dengan indikasi untuk kanker payudara pada wanita tidak hamil, kecuali pada trimester pertama kemoterapi tidak dianjurkan. Radioterapi tidak diberikan selama kehamilan dan terminasi kehamilan tidak akan memperbaiki survival penderita tetapi perlu dipertimbangkan apabila prognosis penderita sangat buruk. Prognosis penderita PABC sama dengan kanker payudara pada wanita yang tidak hamil.

Author(s):  
G. Kasnic ◽  
S. E. Stewart ◽  
C. Urbanski

We have reported the maturation of an intracisternal A-type particle in murine plasma cell tumor cultures and three human tumor cell cultures (rhabdomyosarcoma, lung adenocarcinoma, and osteogenic sarcoma) after IUDR-DMSO activation. In all of these studies the A-type particle seems to develop into a form with an electron dense nucleoid, presumably mature, which is also intracisternal. A similar intracisternal A-type particle has been described in leukemic guinea pigs. Although no biological activity has yet been demonstrated for these particles, on morphologic grounds, and by the manner in which they develop within the cell, they may represent members of the same family of viruses.


Author(s):  
John L. Swedo ◽  
R. W. Talley ◽  
John H. L. Watson

Since the report, which described the ultrastructure of a metastatic nodule of human breast cancer after estrogen therapy, additional ultrastructural observations, including some which are correlative with pertinent findings in the literature concerning mycoplasmas, have been recorded concerning the same subject. Specimen preparation was identical to that in.The mitochondria possessed few cristae, and were deteriorated and vacuolated. They often contained particulates and fibrous structures, sometimes arranged in spindle-shaped bundles, Fig. 1. Another apparent aberration was the occurrence, Fig. 2 (arrows) of linear profiles of what seems to be SER, which lie between layers of RER, and are often recognizably continuous with them.It was noted that the structure of the round bodies, interpreted as within autophagic vacuoles in the previous communication, and of vesicular bodies, described morphologically closely resembled those of some mycoplasmas. Specifically, they simulated or reflected the various stages of replication reported for mycoplasmas grown on solid nutrient. Based on this observation, they are referred to here as “mycoplasma-like” structures, in anticipation of confirmatory evidence from investigations now in progress.


2010 ◽  
Vol 34 (8) ◽  
pp. S49-S49
Author(s):  
Lei Wang ◽  
Xun Zhou ◽  
Lihong Zhou ◽  
Yong Chen ◽  
Xun Zhu ◽  
...  

2010 ◽  
Vol 34 (8) ◽  
pp. S47-S47
Author(s):  
Guopei Zheng ◽  
Sisi Yi ◽  
Yafei Li ◽  
Fangren Kong ◽  
Yanhui Yu ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A741-A741
Author(s):  
P ANG ◽  
D SCHRAG ◽  
K SCHNEIDER ◽  
K SHANNON ◽  
J JOHNSON ◽  
...  

Ob Gyn News ◽  
2005 ◽  
Vol 40 (8) ◽  
pp. 39
Author(s):  
Bruce Jancin
Keyword(s):  

Ob Gyn News ◽  
2008 ◽  
Vol 43 (2) ◽  
pp. 18
Author(s):  
BRUCE JANCIN
Keyword(s):  

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