scholarly journals CT-Scan vs MRI in Diagnosing Laryngeal Carcinoma

2020 ◽  
Vol 8 (1) ◽  
pp. 54-57
Author(s):  
Mohammed Nizamuddin ◽  
Mohammed Naseeruddin ◽  
Anand Abkari
Keyword(s):  
Ct Scan ◽  
Laryngeal Carcinoma ◽  
Ct Scanning ◽  
High Rate ◽  
Pathological Examination ◽  
Glottic Cancer ◽  
Mri Imaging ◽  
Early Glottic Cancer ◽  
Preoperative Stage ◽  
Larynx Surgery

Background: MRI imaging offers more sensitivity than CT to cartilage invasion but results in a high rate of false-positive studies which decreases their overall accuracy. The objective is to compare accuracy of CT scan vs MRI in the laryngeal carcinoma. Subjects and Methods: All patients have been diagnosed, with and without contrast, including neck MRI and CT. In order to prevent invalidation, before laryngeal biopsy, MRI and CT scanning have been done such that the images are not altered by peri tumorous inflammation. Results: The MRI classification was right  for 20 out of 25 patients (80 percent) and 5 outsized cases: three cT1b lesions were pT1a and two cT1a lesions were squamous cell papilloma’s during pathological examination. CT was accurately identified in 17 out of 25 patients (68%), with 8 understated cases: 3 cT1a lesions by     CT were pT1b, 3 cT1a lesions were pT3, and 2 tumours had not been found in the CT scan. Conclusion: Our research showed that MRI in preoperative stage early glottic cancer is more sensitive than CT to accurately select eligible patients for conservatory larynx surgery like super cricoid laryngectomy and cordectomy.

Comparison of Voice Outcomes in Early Glottic Cancer Patients after Laser Surgery or Radiotherapy

2012 ◽  
Vol 55 (11) ◽  
pp. 701 ◽  
Author(s):  
Su Hyun Ahn ◽  
Jun Hyun Kim ◽  
Su Hyun Lee ◽  
Woo Jin Kim ◽  
Dong-Hoon Kim ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Laser Surgery ◽  
Glottic Cancer ◽  
Early Glottic Cancer

scholarly journals Evolution of voice after transoral laser cordectomy for precancerous lesions and early glottic cancer

2021 ◽  
Author(s):  
Lucia Staníková ◽  
Karol Zeleník ◽  
Martin Formánek ◽  
Jana Seko ◽  
Radana Walderová ◽  
...  
Keyword(s):  
Precancerous Lesions ◽  
Voice Quality ◽  
Quality Parameters ◽  
Substantial Improvement ◽  
Glottic Cancer ◽  
Early Glottic Cancer ◽  
Post Surgery ◽  
Group I ◽  
Group Ii ◽  
Laser Cordectomy

Abstract Purpose To evaluate voice quality evolution after a transoral laser cordectomy (TLC) for precancerous lesions and early glottic cancer. Methods This prospective study enrolled 18 patients scheduled for TLC for high-grade dysplasia, Tis, T1, and T2 glottic squamous cell cancers, from May 2017 to March 2020. Patients were grouped according to the extent of TLC: Group I (n = 11, 61.1%): unilateral subepithelial or subligamental cordectomy; Group II (n = 7, 38.9%): unilateral transmuscular, total, or extended cordectomy. Voice quality parameters, including dysphonia grade (G), roughness (R), breathiness (B), maximal phonation time (MPT), jitter, and shimmer, were evaluated before, and at 6 weeks and 6 months after the TLC. Results In Group I, the degree of G and R items remained without substantial improvement 6 weeks after surgery; however, improved above the pre-surgery level up to 6 months after surgery. The MPT, jitter, and shimmer did not change significantly at 6 weeks or 6 months post-TLC. In Group II, G, R, and B remained significantly impaired even 6 months post-surgery. Jitter, and shimmer worsened at 6 weeks, but reached preoperative levels at 6 months post-surgery. MPT was significantly worse at 6 weeks and remained deteriorated at 6 months post-surgery. All measured parameters were significantly worse in Group II than in Group I at 6 weeks and 6 months post-surgery. No patient required a phonosurgical procedure. Conclusion After a TLC, voice quality evolution depended on the extent of surgery. It did not improve at 6 weeks post-surgery. Improvements in less extent cordectomies occurred between 6 weeks and 6 months post-surgery. Understanding voice development over time is important for counseling patients when considering phonosurgical procedures.

Transoral laser microsurgery in early glottic cancer involving the anterior commissure

2019 ◽  
Vol 276 (3) ◽  
pp. 837-845 ◽  
Author(s):  
Christian Jacobi ◽  
Raffaela Freundorfer ◽  
Maximilian Reiter
Keyword(s):  
Anterior Commissure ◽  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Early Glottic Cancer

scholarly journals Image Registration of 18F-FDG PET/CT Using the MotionFree Algorithm and CT Protocols through Phantom Study and Clinical Evaluation

Healthcare ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 669
Author(s):  
Deok-Hwan Kim ◽  
Eun-Hye Yoo ◽  
Ui-Seong Hong ◽  
Jun-Hyeok Kim ◽  
Young-Heon Ko ◽  
...  
Keyword(s):  
Ct Scan ◽  
Ct Scanning ◽  
Motion Artifacts ◽  
Scanning Time ◽  
Pet Ct ◽  
Static Images ◽  
Type C ◽  
Natural Breathing ◽  
Fdg Pet Ct ◽  
Patient Studies

We evaluated the benefits of the MotionFree algorithm through phantom and patient studies. The various sizes of phantom and vacuum vials were linked to RPM moving with or without MotionFree application. A total of 600 patients were divided into six groups by breathing protocols and CT scanning time. Breathing protocols were applied as follows: (a) patients who underwent scanning without any breathing instructions; (b) patients who were instructed to hold their breath after expiration during CT scan; and (c) patients who were instructed to breathe naturally. The length of PET/CT misregistration was measured and we defined the misregistration when it exceeded 10 mm. In the phantom tests, the images produced by the MotionFree algorithm were observed to have excellent agreement with static images. There were significant differences in PET/CT misregistration according to CT scanning time and each breathing protocol. When applying the type (c) protocol, decreasing the CT scanning time significantly reduced the frequency and length of misregistrations (p < 0.05). The MotionFree application is able to correct respiratory motion artifacts and to accurately quantify lesions. The shorter time of CT scan can reduce the frequency, and the natural breathing protocol also decreases the lengths of misregistrations.

Expression and mutational analysis of Cip/Kip family in early glottic cancer

2015 ◽  
Vol 129 (2) ◽  
pp. 168-173 ◽  
Author(s):  
D-K Kim ◽  
J H Lee ◽  
O J Lee ◽  
C H Park
Keyword(s):  
Dna Methylation ◽  
Polymerase Chain Reaction ◽  
Kinase Inhibitors ◽  
Mutational Analysis ◽  
Glottic Cancer ◽  
Cyclin Dependent Kinase ◽  
Chain Reaction ◽  
Single Strand Conformational Polymorphism ◽  
Early Glottic Cancer ◽  
Polymerase Chain

AbstractBackground:Genetic alteration of cyclin-dependent kinase inhibitors has been associated with carcinogenesis mechanisms in various organs.Objective:This study aimed to evaluate the expression and mutational analysis of Cip/Kip family cyclin-dependent kinase inhibitors (p21CIP1/WAF1, p27KIP1 and p57KIP2) in early glottic cancer.Methods:Expressions of Cip/Kip family and p53 were determined by quantitative reverse transcription polymerase chain reaction and densitometry. For the analysis of p21 inactivation, sequence alteration was assessed using single-strand conformational polymorphism polymerase chain reaction. Additionally, the inactivation mechanism of p27 and p57 were investigated using DNA methylation analysis.Results:Reduced expression of p27 and p57 were detected in all samples, whereas the expression of p21 was incompletely down-regulated in 6 of 11 samples. Additionally, single-strand conformational polymorphism polymerase chain reaction analysis showed the p53 mutation at exon 6. Methylation of p27 and p57 was detected by DNA methylation assay.Conclusion:Our results suggest that the Cip/Kip family may have a role as a molecular mechanism of carcinogenesis in early glottic cancer.

scholarly journals Prognostic significance of the DNA ploidy of the early glottic cancer.

1990 ◽  
Vol 93 (8) ◽  
pp. 1171-1178 ◽  
Author(s):  
NORIO YASUDA ◽  
ATSUKO OMORI ◽  
TATSUYA GOTO ◽  
YASUO HISA ◽  
YASUSHI MURAKAMI ◽  
...  
Keyword(s):  
Dna Ploidy ◽  
Prognostic Significance ◽  
Glottic Cancer ◽  
Early Glottic Cancer

Contemporary Surgical Management of Early Glottic Cancer

2015 ◽  
Vol 48 (4) ◽  
pp. 611-625 ◽  
Author(s):  
Dana M. Hartl ◽  
Daniel F. Brasnu
Keyword(s):  
Surgical Management ◽  
Glottic Cancer ◽  
Early Glottic Cancer

scholarly journals ‘Peripheric’ pancreatic cysts: performance of CT scan, MRI and endoscopy according to final pathological examination

HPB ◽  
2015 ◽  
Vol 17 (6) ◽  
pp. 485-489 ◽  
Author(s):  
P. Duconseil ◽  
O. Turrini ◽  
J. Ewald ◽  
J. Soussan ◽  
A. Sarran ◽  
...  
Keyword(s):  
Ct Scan ◽  
Pathological Examination ◽  
Pancreatic Cysts
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