scholarly journals Elderly-onset rheumatoid arthritis: an outlook from a practicing rheumatologist

2020 ◽  
Vol 58 (4) ◽  
pp. 447-450
Author(s):  
Ch. Baimukhamedov

All current challenges and concerns associated with rheumatoid arthritis (RA) in the elderly are analyzed from the point of view of a practicing rheumatologist, including issues of terminology and diagnostics, the need to develop classification criteria for RA presenting at old age. This paper also discusses RA management in the elderly during the coronavirus disease 2019 (COVID-19) pandemic. A multicenter international study, initiated by the League of Eurasian Rheumatologists, can provide necessary insight to develop unified recommendations for RAP. 

2016 ◽  
Vol 10 (1) ◽  
pp. 793-796 ◽  
Author(s):  
Takatomo Mine ◽  
Koichiro Ihara ◽  
Hiroyuki Kawamura ◽  
Ryutaro Kuriyama ◽  
Ryo Date

Elderly onset Rheumatoid arthritis (EORA) has important clinical distinctions when compared with younger onset RA (YORA). In knee arthritis of elderly patients, infection, crystal-induced arthritis or EORA should be suspected if elevation of CRP in the preoperative examination and turbid joint effusion in their knee joint are found. Furthermore, if joint swelling and effusion remain after performing total knee arthroplasty (TKA), the infection after TKA, implant debris-related arthritis and EORA should be considered. However, it is difficult to diagnose patients as EORA if Rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody (ACPA) are negative. The differential diagnosis is very important.


2021 ◽  
pp. jrheum.201135
Author(s):  
Sae Ochi ◽  
Fumitaka Mizoguchi ◽  
Kazuhisa Nakano ◽  
Yoshiya Tanaka

Objective Increasing numbers of patients are developing rheumatoid arthritis (RA) at an older age, and optimal treatment of elderly-onset RA (EORA) patients is attracting greater attention. This study aimed to analyze the efficacy and safety of biological/targeted synthetic disease-modifying anti-rheumatic drugs (b/tsDMARDs) in EORA and non-EORA elderly patients. Methods A cohort of RA patients treated with b/tsDMARDs were retrospectively analyzed. Among patients who were ≥60 years old, those who developed RA after age 60 years were categorized as EORA, while others were categorized as non-EORA elderly. Disease activity were compared between the EORA and non-EORA elderly groups. Results In total, 1,040 patients were categorized as EORA and 710 as non-EORA elderly. There were not significant differences in characteristics at baseline between the two groups. The proportion of patients with low and high disease activity was comparable at week 2, 22 and 54 between in the EORA and the non-EORA elderly group. There was not significant difference in reasons of the discontinuation of b/tsDMARDs between the two groups. Elderly onset did not affect changes in CDAI and HAQ-DI as well as reasons of the discontinuation between the two groups. The trajectory analysis on CDAI-responses to b/tsDMARDs for 54 weeks identified three response patterns. The proportions of patients categorized into each group and CDAI-response trajectories to b/tsDMARDs were very similar between EORA and non-EORA elderly patients. Conclusion CDAI response patterns to b/tsDMARDs and hazard ratio of adverse events were similar between EORA and non-EORA elderly patients.


2010 ◽  
Vol 14 (4) ◽  
pp. 227-233 ◽  
Author(s):  
Hyun Ok Kim ◽  
Ho Sung Yoon ◽  
Seung Ki Kwok ◽  
Ji Hyeon Ju ◽  
Kyung Su Park ◽  
...  

2010 ◽  
Vol 77 (4) ◽  
pp. 290-296 ◽  
Author(s):  
Martin Soubrier ◽  
Sylvain Mathieu ◽  
Sarah Payet ◽  
Jean-Jacques Dubost ◽  
Jean-Michel Ristori

Author(s):  
Melania Martínez-Morillo ◽  
águeda Prior-Español ◽  
Anahy Brandy-Garcia ◽  
Susana Holgado ◽  
María Aparicio-Espinar ◽  
...  

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