scholarly journals Erroneous diagnosis of genital lichen planus

2021 ◽  
Vol 2 (3) ◽  
pp. 58-60
Author(s):  
Evgenia V. Dvoryankova ◽  
Keyword(s):  
Lichen Planus ◽  
Case History ◽  
Clinical Case ◽  
Initial Visit ◽  
Dermatology Clinic ◽  
Erroneous Diagnosis ◽  
Repeat Visit ◽  
Topical Emollient

Clinical case of 62 year old patient complaining of rash on the glans of the penis is reported. It was known from the case history that genital rashes first appeared in spring 2020 in the form of two “red dots” associated with no subjective sensations. During the initial visit to dermatology clinic (in London) in June 2020 no diagnosis was established; antibiotics and application of topical emollient were prescribed. The patient did not take treatment as prescribed. During the repeat visit to dermatologist (in Moscow) lichen planus was diagnosed; application of alclometasone dipropionate cream on the rashes 2 times a day was prescribed. Rashes resolved completely in 10 days with treatment.

Fixed Full-Arch Implant-Supported Prostheses in a Patient with Epidermolysis Bullosa: A Clinical Case History Report

2015 ◽  
Vol 28 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Rubén Agustín-Panadero ◽  
Sonia Gomar-Vercher ◽  
David Peñarrocha-Oltra ◽  
Marcelo Guzmán-Letelier ◽  
Miguel Peñarrocha-Diago
Keyword(s):  
Epidermolysis Bullosa ◽  
Case History ◽  
Clinical Case

scholarly journals Branchio-oto-renal syndrome: a clinical case

2019 ◽  
Vol 25 (1) ◽  
pp. 5
Author(s):  
Xavier Lagarde ◽  
Mathilde Fenelon ◽  
Jean Christophe Fricain
Keyword(s):  
Medical History ◽  
Rare Disease ◽  
Genetic Study ◽  
Clinical Case ◽  
Autosomal Dominant ◽  
Clinical Criteria ◽  
Dermatology Clinic ◽  
Family Medical History ◽  
The Family ◽  
Renal Abnormalities

Observation: A 19-week-old patient seen in an oral dermatology clinic had small labial commissures pits associated with auricular abnormalities. Similar clinical elements were found in the family medical history. A diagnosis of branchio-oto-renal syndrome (BOR) was quickly evoked. Commentary: BOR syndrome is a rare disease. This autosomal dominant pathology is characterized by facial lesions and renal abnormalities. Diagnosis is based on many clinical criteria. An optional genetic study can sometimes assist in diagnosis.

scholarly journals Clinicopathological Correlate of Papulosquamous Skin Disorder in a Tertiary Health Care

2020 ◽  
pp. 54-65
Author(s):  
B. A. Ukonu ◽  
P. U. Ibekwe ◽  
B. A. Abimiku
Keyword(s):  
Lichen Planus ◽  
Clinical Diagnosis ◽  
Skin Disorder ◽  
Lymphocytic Infiltrate ◽  
Histopathological Diagnosis ◽  
Dermatology Clinic ◽  
Lichen Simplex Chronicus ◽  
Clinical Description ◽  
Histological Confirmation ◽  
Male To Female

Papulosquamous skin disorder is one of the frequently seen skin dermatoses; but due to clinical and morphological overlap, it is sometimes difficult to make a straight forward clinical diagnosis without histological confirmation. This study seeks to examine the level of correlation between clinical diagnosis and histological confirmation. Medical records of subjects diagnosed at the Dermatology clinic with papulosquamous skin disorder between January 2017 and December 2019 were retrieved. Their bio data, clinical description of their lesions, clinical diagnosis and histopathological report were noted and analyzed with SPSS version 23 of the 88 patients with clinical diagnosis of a papulosquamous skin disease, 62 had record of skin biopsy result; these were included in the data analysis. The mean age was 39.1± 13.8 years (age ranged from 3-64 years). Ratio of male to female was 1.7:1 Thirty-four 34 (54.8%) were clinically diagnosed as lichen planus, 25 (40.3%) as psoriasis, 1(1.6%) each as parapsoriasis, lichen nitidus and lichen simplex chronicus. Histopathological diagnosis was the same in 26 cases of lichen planus, 19 of psoriasis and for the above mentioned disorders. Common histological findings for lichen planus were acanthosis 88.5%, hyperkeratosis (30.8%), parakeratosis (3.8%), papillomatosis (61.5%), hypergranulosis (3.8%) and band-like lymphocytic infiltrate (57.7%). While acanthosis (68.4%), Elongated rete ridges (84.2%); band-like lymphocytic infiltrate (78.9%) and dermal dilated blood vessels (5.3%) were seen in psoriasis. In conclusion: We observed 77.4% accuracy in diagnosis of papulosquamous skin disorder.

Indian Dermoscopic Study of Forty Six Cases of Lichen Planus Pigmentosus - New Dermoscopy Signs Discovered

2018 ◽  
Vol 3 (02) ◽  
Author(s):  
Rahul Kumar Sharma, Rajendra Kumar Sharma
Keyword(s):  
Lichen Planus ◽  
Smart Phone ◽  
Poor Response ◽  
Response To Treatment ◽  
Dermatology Clinic ◽  
Single Marker ◽  
Brownish Black ◽  
Brown Pigmentation ◽  
Black Pigmentation ◽  
Very High

Lichen planus pigmentosus (LPP) is a atypical pigmented variety of lichen planus. Lichen planus pigmentosus is an unpredictable relapsing idiopathic dermatosis with periods of activation and remission with poor response to treatment and may leads to cosmetically disfiguring post inflammatory pigmentation. Aim - To study dermoscopic features of untreated cases of Lichen planus pigmentosus. Study subjects - All the patients who attended the dermatology clinic from November 2015 to November 2017 with the clinical diagnosis of LPP and who fulfilled the inclusion and exclusion criteria. Methodology - All the patients who attended the dermatology clinic with the diagnosis of LPP were examined by a dermatoscope. Dermoscopy was performed with DL4 dermatoscope. The images were further magnified with smart phone. Results - Our study showed various dermoscopic signs in cases of LPP like annular granular pattern (35 cases), annular globular pattern (5 cases), homogeneous brown pigmentation (12 cases), homogeneous brownish black pigmentation (8 cases), brownish ovoid nests (3 cases), bluish blackish fine dots (4 cases), Wickham’s striae(2 cases) and pigmented targetoid globules(3 cases). Discussion - Dermatoscope is an indispensible valuable tool in clinical practice which helps in making early lucid diagnosis of LPP with very high accuracy. Our study showed that annular granular pattern is the commonest pattern in Indian LPP cases followed by homogeneous brown pigmentation. In our Indian LPP dermoscopy study we discovered three novel dermoscopic signs which includes brownish globular nests, pigmented targetoid globules and bluish blackish fine dots. In our study we got few unique cases where Wickham’s striae was also present with other dermoscopic signs which supports the link of LPP to lichen planus. Dermatoscopic diagnosis of LPP is made by combination of various signs and should not be dependent on the presence of single marker.

Clinical Case Study: Muscle Tension Dysphonia

2021 ◽  
pp. 1-3
Author(s):  
Adrianna C. Shembel ◽  
Cory Atkinson ◽  
Lesley Childs
Keyword(s):  
Case History ◽  
Clinical Case ◽  
Muscle Tension ◽  
Problem Based Learning ◽  
Voice Assessment ◽  
Muscle Tension Dysphonia ◽  
Clinical Case Study ◽  
Link Type ◽  
Perceptual Assessment

Purpose: The purpose of this problem-based learning case study is to review and interact with a clinical case involving a patient diagnosed with muscle tension dysphonia. Included in the case study is a case history, a voice sample, and a laryngeal exam. Conclusions: The case study provides an opportunity to practice conducting an auditory-perceptual assessment and acoustic voice assessment on the provided voice sample. The case study also provides the opportunity to rate endoscopic and stroboscopic parameters on the laryngeal exam. Supplemental Material https://doi.org/10.23641/asha.16799641

scholarly journals Topical Calcineurin Inhibitor Tacrolimus in Orabase: an Alternative Treatment for Erosive Oral Lichen Planus

2020 ◽  
Vol 71 (4) ◽  
pp. 438-445
Author(s):  
Mihaela Paula Toader ◽  
Madalina Mocanu ◽  
Stefan Toader ◽  
Roxana Irina Iancu ◽  
Tatiana Taranu
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Large Scale ◽  
Lymphocyte Activation ◽  
Topical Tacrolimus ◽  
Beneficial Effects ◽  
Dermatology Clinic ◽  
Cellular Immune ◽  
The University ◽  
Oral Lichen

Tacrolimus, a macrolide with immunosuppressive properties through the inhibition of T-lymphocyte activation, was approved as a second line topical treatment for atopic dermatitis, but has been largely used with beneficial effects in other dermatological conditions that involve a disregulation of the cellular immune response. Oral lichen planus is a T-cell�mediated autoimmune disease in which autocytotoxic CD8+ T cells trigger apoptosis of oral epithelial cells. Our study aimed to analyze the clinical efficacy of tacrolimus 0.03% and 0.1% in orabase as monotherapy on oral erosive lesions of lichen planus, in a group of 20 patients consulted in the Dermatology Clinic of the University C.F. Hospital Iasi during a period of five years. Our results show total or partial remission of oral erosive lesions in most patients at 3 months follow-up. However, after treatment discontinuation relapses are common, which is why intermittent use of topical tacrolimus is needed for longer periods to prevent recurrences. Further large scale studies are necessary to establish efficacy and safety profile of prolonged use of tacrolimus on mucosal membranes, as well as the most appropriate vehicle and concentration.

scholarly journals Combined dermatological pathology complicated by Gottron’s carcinoid papillomatosis

2020 ◽  
Vol 4 (10) ◽  
pp. 652-658
Author(s):  
M.M. Tlish ◽  
◽  
N.L. Sycheva ◽  
V.V. Starostenko ◽  
O.A. Sidorenko ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Autoimmune Thyroiditis ◽  
Clinical Picture ◽  
Clinical Case ◽  
Pathological Process ◽  
Puva Therapy ◽  
Pathogenetic Mechanism ◽  
Skin Biopsies ◽  
Vegetation Characteristic ◽  
Russian Medical

Combined pathology is quite common and relevant in dermatology, but at the same time it is insufficiently studied. There is a few available literature data on the multimorbidity of immune-dependent dermatitis. The article presents a clinical case of a patient with diseases united by a common pathogenetic mechanism (vitiligo, lichen planus (LP), autoimmune thyroiditis) and then subjected to a causality transformation with the Gottron’s carcinoid papillomatosis (GCP) development at sites of occurred dermatoses. Papillomatous projections and vegetation characteristic of CGP almost completely replaced the original papular rash characteristic of lichen planus. It changed the clinical picture of the main pathological process, complicated its course, which in turn caused difficulties in timely diagnosis. Clinical and histomorphological examinations of skin biopsies were performed to verify the diagnosis. Histologically, GCP was manifested by epidermal pseudoepitheliomatous hyperplasia at the site lichen planus and vitiligo foci. This clinical case is of interest due to the rare combination of lichen planus with vitiligo in the setting of autoimmune thyroiditis; it confirms the previously expressed assumptions about the possibility of immune-dependent diseases combination. KEYWORDS: multimorbidity, vitiligo, lichen planus, Gottron’s carcinoid papillomatosis, autoimmune thyroiditis, histology, PUVA therapy, cryolysis. FOR CITATION: Tlish M.M., Sycheva N.L., Starostenko V.V. et al. Combined dermatological pathology complicated by Gottron’s carcinoid papillomatosis. Russian Medical Inquiry. 2020;4(10):652–658. DOI: 10.32364/2587-6821-2020-4-10-652-658.

scholarly journals Lichen Planus and Hepatitis C Virus Infection: A clinical Evaluation of 168 Cases

2018 ◽  
Vol 10 (2) ◽  
pp. 37-41
Author(s):  
Farrokh Rad ◽  
Ebrahim Ghaderi ◽  
Bahram Nikkhoo ◽  
Mohammad Aziz Rasouli
Keyword(s):  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Chronic Liver Disease ◽  
Lichen Planus ◽  
Chronic Liver ◽  
Hcv Infection ◽  
Common Site ◽  
Hepatitis C Infection ◽  
Dermatology Clinic

Abstract Introduction. Hepatitis C virus (HCV) infection is one of the factors which can lead to a chronic liver disease and hepatocellular carcinoma. There have been several reports on the association of oral lichen planus with hepatic disorders, i.e. hepatitis C infection in particular. Considering the controversies about the association of lichen planus with HCV infection on one hand and considerable impact of hepatitis C on the occurrence of chronic liver disease on the other hand, we investigated the association between lichen planus and HCV infection in Sanandaj City. Methods. This cross sectional study included 168 patients with lichen planus, who were referred to the Dermatology Clinic of Besat Hospital between 2014 and 2016. The diagnosis of lichen planus was made by our dermatologist and HCV antibody titer was determined for every patient. Results. Mean age of the patients was 39.7±13.3 years and mean duration of the disease was 14.8 months. 107 (63.7%) patients were men. The highest frequency of lichen planus was recorded in the housewives (30.4%). In 52 (31%) patients the genital area was involved and it was the most common site. In 6 (3.6%) patients the oral mucosa was involved and it was the least common site in our study. Only 4 (2.7%) patients had family history of lichen planus. None of 168 patients included in this study was found to have HCV infection. Conclusion. In this study, we found no relationship between lichen planus and HCV infection. Yet, the exact mechanism underlying the occurrence of lichen planus in the patients with HCV infection has not been determined. Therefore more studies on this subject are recommended.

Unilateral Vocal Fold Paralysis: The “Trifecta”—Dysphonia, Dysphagia, and Dyspnea

2021 ◽  
pp. 1-4
Author(s):  
Michelle Adessa
Keyword(s):  
Treatment Planning ◽  
Case History ◽  
Vocal Fold ◽  
Clinical Case ◽  
Acoustic Analysis ◽  
Vocal Fold Paralysis ◽  
Unilateral Vocal Fold Paralysis ◽  
Voice Assessment ◽  
Perceptual Analysis ◽  
Audio Files

Purpose: A clinical case of unilateral vocal fold paralysis is presented with case history, auditory-perceptual analysis and accompanying audio files and ratings, videostroboscopic files and ratings, and acoustic analysis, as well as impressions and plan for treatment. Method: A single clinical case of unilateral vocal fold paralysis is presented for learning purposes. Results: Clinical keys are provided for learning. Conclusion: Learners will be able to follow a clinical case to aid in perceptual, videostroboscopic, acoustic, and voice assessment and goal and treatment planning. Supplemental Material https://doi.org/10.23641/asha.16799563

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