Nifuroxazide Pharmaceutical Preparations in the Russian Federation. Publication One: Nomenclature, Chemical and Pharmaceutical Characteristics of the Preparations’ Composition

One of the most used antimicrobial nitrofurans in Russian medical practice is nifuroxazide, which is distinguished by high therapeutic efficacy, drug safety, as well as economic availability in the treatment of acute bacterial diarrhea without deterioration of the general condition, fever, and intoxication. In the Russian Federation (RF), nifuroxazide preparations in general circulation are supplied by 19 domestic and foreign pharmaceutical organizations. The aim of this study was to analyze the nomenclature, as well as chemical and pharmaceutical characteristics of excipients (EXs) in the composition of nifuroxazide preparations, which received state registration in the RF. A comparative study of the chemical and pharmaceutical characteristics of EXs of 42 nifuroxazide preparations in the form of capsules, tablets, and suspension for oral administration was carried out. The pharmaco-economic status is noted and the demand prospects for all forms of nifuroxazide preparations in the RF are outlined. Quantitative and qualitative differences in the composition of the EXs of a number of nifuroxazide preparations in the form of capsules and suspensions has been shown.

Vestibular disorders in elderly people (conference proceedings)

The causes and clinical manifestations of vestibulopathies in elderly people are extremely diverse. The experts of CON-MED.RU, the professional information resource for healthcare specialists, the expert on gerontology Elen A. Mkhitaryan (PhD, head of the laboratory of neurogeriatrics and cognitive impairment under the Science section, Pirogov Russian National Research Medical University, Russian Clinical and Research Center of Gerontology), and one of the most recognized Russian neurologists, the expert on vertigo Maxim V. Zamergrad (D. Sci. (Med.), professor at the Department of Neurology with the course of reflexology and manual therapy, Russian Medical Academy of Continuous Professional Education), clarified this issue, which was difficult for clinicians.

A few words about the state of the Russian medical periodicals in 1922

The war, the revolution and the economic devastation that followed them dealt a heavy blow to the Russian scientific press in general and the Russian medical press in particular. others, after several attempts to come out in a reduced size, they completely ceased to appear in the light. But our scientific medical thought did not die out. Despite the extremely difficult external conditions, it continued to work hard, and as a result, as soon as the slightest opportunity arose, medical journals and newspapers began to reappear in various scientific centers of Russia. and of a special nature. Strictly speaking, there were too many of them in the coming year, if we take into account the available scientific forces and material resources of the country namely, over 50 and, naturally, the quantitative aspect of the matter turned out to be at the expense of the qualitative one. Many of these journals were published in the reporting year in the amount of only 2-3 of a very small volume. not able to boast of either their content or their appearance. Hopefully, they are just seeds from which lush sprouts will subsequently develop.

Russian medical educational resources the era of the Covid-19 pandemic

Издание посвящено вопросам медицинского электронного образования эпохи пандемии в стране. Показан опыт, формы, средства организации современного медицинского образования. Издание адресовано научным работникам, педагогам, студентам, а также широкому кругу читателей, интересующихся проблемами современного медицинского образования.

Export of medical services: how to increase the competitiveness of Russian healthcare organizations

The goal of the Federal Project “Development of the export of medical services, approved by the Government of the Russian Federation in 2019 (included in the national project ‘Healthcare’) is to increase the export of Russian medical services by 4 times (in US dollars) by 2025. In this regard, a special role is played by the professional and ethical characteristics of medical personnel, which can have a significant impact on improving the competitiveness of medical organizations. One of these competitive advantages can be the introduction of a special corporate culture of personnel in Russian medical organizations, which includes taking into account the interests of patients belonging to different ethnic and religious groups. The purpose of the study: to determine the competitiveness of Russia in the field of export of medical services and to consider ways to improve it (competitiveness), in particular, through the introduction of a corporate culture aimed at taking into account the interests of various confessional and ethnic groups of the personnel of medical organizations. Methodology: analysis of secondary data and publications on the research topic. Results: based on the analysis of secondary data, as well as publications on the topic of the study, Russia’s place in the field of medical services export is determined, the competitive advantages and disadvantages of Russian medical services from the point of view of the 5P model of the marketing complex are revealed. It is proposed to improve the corporate culture of the personnel of Russian medical organizations. Discussion: one of the possible ways to improve the basics of corporate culture is to provide additional training for staff on the basics of interaction with patients belonging to different ethnic and religious groups. Conclusion: improving the competitiveness of Russian medical organizations can be achieved by competently promoting the quality characteristics of the staff, such as a tolerant attitude towards patients belonging to different religious and ethnic groups, and taking into account their interests in the process of treatment and interaction.

Consensus of experts from the Russian Medical Society of Arterial Hypertension. Arterial hypertension and erectile dysfunction

Sexual health is an essential part of overall health, and an active and healthy sex life is an important aspect of a good quality of life. Cardiovascular diseases and sexual health disorders have common risk factors (arterial hypertension, diabetes mellitus, dyslipidemia, obesity and smoking) and common pathogenesis (endothelial dysfunction, inflammation and atherosclerosis). All this led to speculations about the pathophysiology and treatment options for sexual dysfunctions. The use of phosphodiesterase type 5 inhibitors has revolutionized the treatment of erectile dysfunction (ED) in men. This article focuses on ED and its relationship with hypertension. This document was created by experts from the Russian Medical Society of Arterial Hypertension with the participation of a member of the European Society of Hypertension Working Group on Sexual Dysfunction and Arterial Hypertension. In recent years, the expert group was very active in educating hypertension specialists and related specialties physicians about ED via numerous lectures at national and international congresses. It has been noted that ED precedes the development of coronary heart disease. The artery diameter hypothesis has been proposed as a possible explanation for this observation. Clinical manifestations of atherosclerotic lesions and/or endothelial dysfunction of the penile arteries may precede those in larger arteries. Patients with hypertension who receive antihypertensive drugs are more likely to suffer from sexual dysfunctions compared to untreated patients. The occurrence of ED appears to be related to the undesirable effects of antihypertensive drugs on the penile tissues. There is information about various effects of antihypertensive drugs on erectile function.

Hypertensic crisis — clinical interpretation of the term

The term «hypertensic crisis» is used to describe a condition that develops over time, and the outcomes depend on both, timing and completeness of medical care and the initial clinical status of the patient. The term «uncontrollable arterial hypertension» in ESC and RSC recommendations (2018–2020) cannot replace the concept of “uncomplicated HC” completely . It is advisable to adhere to the recommendations of the Russian Medical Society for Arterial Hypertension (RMSAH) developed in 2019, in which the division into complicated and uncomplicated HC still remains. In clinical practice, three variants of a signifi cant increase in blood pressure in patients with arterial hypertension should be distinguished: an isolated increase in blood pressure, uncomplicated and complicated HC. It is necessary to stratify patients with uncomplicated HC according to the degree of risk of cardiovascular complications development in order to determine the indications for their hospitalization. The rapid relief of a significant increase in blood pressure should lead to a safe level of patient’s pressure, taking into account the risk of hypotension and hypoperfusion of vital organs and systems.