Henan Oilfield Xiaermen Qianbei block is the medium-deep heavy oil reservoir. Due to the high viscosity of crude oil, formation cementation loose, sand production and reservoir water-sensitive, the pre-trial is less effective. The problem is the inefficiency of steam injection, poor oil-steam ratio, sand production serious, the poor pump efficiency and the abnormal productions. It is important to improve the mobility of heavy oil in the formation and wellbore for the development. According to the reservoir characteristics and the experience of the primary development, the measures which include the high-pressure gravel packing sand control, insulated tubing of steam injection, anti-swelling agent reservoir protection, formation and wellbore viscosity reducer and rod sucker-rod pumping system are carried out in a pilot test of the four wells. After the pilot test, the oil-steam ratio increases from 0.08 to 0.55, the average daily oil production increases from 0.5 tons to 8.0 tons. The pilot test has achieved great success and promoted the application in medium-deep heavy oil thermal recovery in the entire block, simultaneously provided the basis for the efficient development of other similar blocks.