Chapter-08 Macular Diseases

2010 ◽  
pp. 151-164
Author(s):  
Mahesh Sanmugam
Keyword(s):  
Macular Diseases

Test-Retest-Reliability of Computer-Based Metamorphopsia Measurement in Macular Diseases

2020 ◽  
Author(s):  
Daniela Claessens ◽  
Alexander K. Schuster ◽  
Ronald V. Krüger ◽  
Marian Liegl ◽  
Laila Singh ◽  
...  
Keyword(s):  
Macular Edema ◽  
Correlation Coefficient ◽  
Intraclass Correlation Coefficient ◽  
Intraclass Correlation ◽  
Measuring Method ◽  
Repeated Measurements ◽  
Retest Reliability ◽  
Macular Diseases ◽  
Computer Based ◽  
Test Retest Reliability

AbstractIn this study, the test-retest-reliability as one aspect of reliability of metamorphopsia measurements using a computer-based measuring method was determined in patients with macular diseases. Metamorphopsia amplitude, position, and area were quantified using AMD – A Metamorphopsia Detector software (app4eyes GmbH & Co. KG, Germany) in patients with diabetic, myopic, or uveitic macular edema, intermediate or neovascular age-associated macular degeneration, epiretinal membrane, vitelliform maculopathy, Irvine-Gass syndrome, or macular edema due to venous retinal occlusion. The intraclass correlation coefficient (ICC) was calculated in order to determine the repeatability of two repeated measurements and was used as an indicator of the reliability of the measurements. In this study, metamorphopsia measurements were conducted on 36 eyes with macular diseases. Metamorphopsia measurements made using AMD – A Metamorphopsia Detector software were highly reliable and repeatable in patients with maculopathies. The intraclass correlation coefficient of all indices was excellent (0.95 – 0.97). For diseases of the vitreoretinal interface or macular diseases with intra- or subretinal edema, this metamorphopsia measurement represents a supplement for visual function testing in the clinic, as well as in clinical studies.

A Comparison of Radial and Horizontal Macular Optical Coherence Tomography on Detection of Macular Pathology: A Prospective Study at an Academic Institution

2021 ◽  
pp. 247412642199705
Author(s):  
Halward M.J. Blegen ◽  
Samuel D. Hobbs ◽  
Reggie Taylor ◽  
Andrew L. Plaster ◽  
Paul M. Drayna
Keyword(s):  
Optical Coherence Tomography ◽  
Prospective Study ◽  
Macular Degeneration ◽  
Epiretinal Membrane ◽  
Central Serous Chorioretinopathy ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related ◽  
Macular Diseases ◽  
A Prospective Study

Purpose: Optical coherence tomography (OCT) is useful in diagnosing and monitoring retinal pathology such as age-related macular degeneration, diabetic macular edema (DME), central serous chorioretinopathy, and epiretinal membrane, among others. This study compared the ability of horizontal (H) 25-, 13-, and 7-cut macular OCT vs 24-, 12-, and 6-cut radial (R) macular OCT in identifying various macular pathology. Methods: This was a prospective study of 161 established patients evaluated at Wilford Hall Eye Center Retina Clinic between September and October of 2019. Pathology included age-related macular degeneration, central serous chorioretinopathy, DME, and epiretinal membrane, among others. Patients obtained 25-, 13-, and 7-cut H raster OCT as well as 24-, 12-, and 6-cut R OCT. Primary outcomes were sensitivity in detecting macular fluid and each macular abnormality. Results: The 24-cut radial (R24) OCT equally or out-performed the H25 (horizontal 25-cut OCT) in detecting macular fluid across all pathological groups. Generally, a higher number of cuts correlated with better detection of fluid. In detecting any macular abnormalities, H25, R24, and R12 had 100% sensitivity. R6 OCT had near 100% sensitivity across all groups, except for DME (95%). Overall, R OCT had better sensitivity (0.960) than H OCT (0.907) in detecting macular pathology. Conclusions: R outperformed H macular OCT in detecting fluid and other abnormalities. Clinically, both scanning patterns can be used by ophthalmologists in diagnosis and management of commonly encountered macular diseases. Technicians may be able to use a variety of these scans to screen for pathology prior to physician evaluation.

Effect of blue light-filtering intraocular lens on color vision in patients with macular diseases after vitrectomy

2016 ◽  
Vol 36 (6) ◽  
pp. 829-839
Author(s):  
Kumiko Mokuno ◽  
Tetsu Asami ◽  
Norie Nonobe ◽  
Hirotaka Ito ◽  
Kumi Fujiwara ◽  
...  
Keyword(s):  
Color Vision ◽  
Blue Light ◽  
Intraocular Lens ◽  
Macular Diseases

scholarly journals Incidence and impact factors of intraoperative loss of light perception under sub-Tenon’s anesthesia in patients with macular diseases

Eye ◽  
2019 ◽  
Vol 33 (11) ◽  
pp. 1784-1790 ◽  
Author(s):  
Dezhi Zheng ◽  
Zijing Huang ◽  
Guihua Zhang ◽  
Dingguo Huang ◽  
Guoqiao Lin ◽  
...  
Keyword(s):  
Impact Factors ◽  
Light Perception ◽  
Macular Diseases

scholarly journals Subliminal Laser as Additional Therapy to Reduce Intravitreal Injection Number for the Patients with Macular Diseases

2020 ◽  
Vol 18 (1) ◽  
pp. 45-47
Author(s):  
Liene Muceniece ◽  
Dace Markevica
Keyword(s):  
Visual Acuity ◽  
Macular Edema ◽  
Systemic Disease ◽  
Alternative Therapy ◽  
Treatment Method ◽  
Macular Thickness ◽  
Intravitreal Injections ◽  
Macular Diseases ◽  
Significant Difference ◽  
Additional Therapy

SummaryIntroductionIntravitreal injections have become one of the most performed surgical procedures in ophthalmology. There is a need to look for an effective alternative therapy for patients with anti-VEGF complications and systemic disease contraindications.Aim of the studyTo evaluate Subliminal laser effectiveness on reducing macular disease edema.Materials and methodsSubliminal laser treatment was done three times with three month intervals for patients with macular edema due to retinal diseases. On 1st, 3rd, 6th and 9th month visit the best corrected visual acuity, intraocular pressure, macular thickness and macular volume were registered.ResultsMean visual acuity before treatment was 0,52 (SD=0,31) that changed to 0,56 after the 9 month treatment (p>0,05). Mean central macular thickness from 326,12 μm reduced to 308,15 (p=0,76). Without significant difference, inner cycle volume changed from 1353,80 mm3 to 1297,57 mm3 (p=0,81) and outer cycle volume from 1179,4 mm3 to 1112,56 mm3 (p=0,51).ConclusionsSubliminal laser controls macular edema level and could be a solution for patients who cannot afford or are emotionally distressed by monthly intravitreal injections. This treatment method can be used as additional therapy to reduce the number of intravitreal injections.

Retinal Prosthesis in the Treatment of Retinitis Pigmentosa

2021 ◽  
pp. 140-149
Keyword(s):  
Retinitis Pigmentosa ◽  
Retinal Prosthesis ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Cone Dystrophy ◽  
Research Groups ◽  
Retinal Prostheses ◽  
Retinal Degenerations ◽  
Age Related ◽  
Macular Diseases

Retinal prostheses are devices that receive an environmental visual stimulus, process it, and stimulate the degenerated retinal areas in order to produce a functionally efficient visual perception. Indications for implantation of these devices include hereditary retinal degenerations like retinitis pigmentosa, choroideremia, rod-cone dystrophy, and acquired macular diseases like geographic atrophy or fibrosis due to age-related macular degeneration. Clinically applied retinal prosthesis approaches can be classified as; epiretinal, subretinal, suprachoroidal, and scleral (transscleral suprachoroidal). In this paper, approaches of retinal prosthesis research groups, results of clinical trials, and the latest advances in their projects will be provided.

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