scholarly journals Synthesis of Glucuronic Acid Conjugates of Linoleic Acid Metabolites

2013 ◽  
Vol 57 (6) ◽  
pp. 738-743
Author(s):  
Dong Wook Kang
Keyword(s):  
Linoleic Acid ◽  
Glucuronic Acid ◽  
Acid Metabolites

scholarly journals Cyclopentanoids from Cyclopentadiene: Synthesis of (-)-Methyl jasmonate and (+)-12-Oxophytodienoic acid

2013 ◽  
Vol 8 (7) ◽  
pp. 1934578X1300800
Author(s):  
Junzo Nokami ◽  
Kazuhiko Fujii ◽  
Yusuke Mizutani ◽  
Rikiya Omatsu ◽  
Kiyoshi Watanabe ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Methyl Jasmonate ◽  
Nucleophilic Substitution ◽  
Dimethyl Malonate ◽  
Cyclopentane Ring ◽  
Acid Metabolites ◽  
Α Chain

Linoleic acid metabolites (-)-methyl jasmonate and (+)-12-oxophytodienoic acid ((+)-12-oxo-PDA) were prepared from the same precursor (1,2-trans, 1,3- cis, 2′ Z)-2-(pent-2′-enyl)-cyclopent-4-en-1,3-diol which was obtained by regioselective pent-2-enylation of cyclopentadiene and following photooxidation to cis −1,3-diol. A methoxycarbonylmethyl substituent was introduced to the cyclopentane ring via alkylation of the π-allyl palladium intermediate derived from (1 R,2 S,3 S,2′ Z)-3-acetoxy-2-(pent-2′-enyl)cyclopent-4-ene-1-ol with dimethyl malonate for (-)-methyl jasmonate. The α-chain was introduced to the cyclopentane ring via the SN2 type nucleophilic substitution of (1 S,2 R,3 R,2′ Z)-3-acetoxy-2-(pent-2′-enyl)cyclopent-4-ene-1-ol with a dialkylcuprate for (+)-12-oxo-PDA.

scholarly journals Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation

2010 ◽  
Vol 48 (10) ◽  
pp. 1311-1320 ◽  
Author(s):  
Lukas Kubala ◽  
Kara R. Schmelzer ◽  
Anna Klinke ◽  
Hana Kolarova ◽  
Stephan Baldus ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Acute Inflammation ◽  
Acid Metabolites ◽  
Deficient Mice

The Effect of some Inducers of Hepatic Xenobiotic-Metabolizing Enzymes on the Urinary Excretion of d-Glucuronic Acid Metabolites in the Rat

1975 ◽  
Vol 3 (1) ◽  
pp. 188-191
Author(s):  
BRIAN G. LAKE ◽  
RONALD C. LONGLAND ◽  
ROSALYN A. HODGSON ◽  
BRIAN J. SEVERN ◽  
SHARAT D. GANGOLLI ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Glucuronic Acid ◽  
Metabolizing Enzymes ◽  
Xenobiotic Metabolizing Enzymes ◽  
Acid Metabolites

scholarly journals Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry

2012 ◽  
Vol 27 (4) ◽  
pp. 422-432 ◽  
Author(s):  
Zhi-Xin Yuan ◽  
Stanley I. Rapoport ◽  
Steven J. Soldin ◽  
Alan T. Remaley ◽  
Ameer Y. Taha ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Linoleic Acid ◽  
Time Of Flight ◽  
Rat Plasma ◽  
Flight Mass Spectrometry ◽  
Acid Metabolites

Linoleic Acid Metabolites Act to Increase Contractility in Isolated Rat Heart

2002 ◽  
Vol 2 (3) ◽  
pp. 219-230 ◽  
Author(s):  
Lex A. Mitchell ◽  
David F. Grant ◽  
Russell B. Melchert ◽  
Nathan M. Petty ◽  
Richard H. Kennedy
Keyword(s):  
Linoleic Acid ◽  
Rat Heart ◽  
Isolated Rat Heart ◽  
Acid Metabolites ◽  
Isolated Rat
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