scholarly journals Advanced POEMS syndrome treated with high-dose melphalan followed by autologous blood stem cell transplantation: a single-center experience

2014 ◽  
Vol 49 (1) ◽  
pp. 42 ◽  
Author(s):  
Il-Young Jang ◽  
Dok Hyun Yoon ◽  
Shin Kim ◽  
Kyoungmin Lee ◽  
Kwang-Kuk Kim ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Autologous Blood ◽  
Poems Syndrome ◽  
High Dose ◽  
Single Center ◽  
Single Center Experience ◽  
High Dose Melphalan ◽  
Blood Stem Cell Transplantation

POEMS syndrome treated with melphalan high-dose therapy and autologous blood stem cell transplantation: a single-institution experience

2012 ◽  
Vol 91 (9) ◽  
pp. 1419-1425 ◽  
Author(s):  
Gabriela B. Thoennissen ◽  
Nils H. Thoennissen ◽  
Fleur Fritz ◽  
Andreas Hilbig ◽  
Andrea Kerkhoff ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Autologous Blood ◽  
Poems Syndrome ◽  
High Dose ◽  
Single Institution ◽  
High Dose Therapy ◽  
Dose Therapy ◽  
Blood Stem Cell Transplantation

High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome

Blood ◽  
2002 ◽  
Vol 99 (8) ◽  
pp. 3057-3059 ◽  
Author(s):  
Arnaud Jaccard ◽  
Bruno Royer ◽  
Dominique Bordessoule ◽  
Jean-Claude Brouet ◽  
Jean-Paul Fermand
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Plasma Cell ◽  
Autologous Blood ◽  
Poems Syndrome ◽  
High Dose ◽  
High Dose Therapy ◽  
Dose Therapy ◽  
Blood Stem Cell Transplantation

Abstract We treated 5 patients with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome and multifocal bone lesions or diffuse bone marrow plasmacytic infiltration with high-dose therapy (HDT) and autologous blood stem cell transplantation. In all cases, the treatment produced remission of plasma cell proliferation associated with marked improvement in the patients' performance status, neurologic symptoms, and other manifestations of the syndrome. HDT with stem cell support should be investigated further as a therapeutic option in patients with POEMS syndrome and disseminated plasma cell dyscrasia.

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