Idiopathic Harlequin syndrome – case report

Here we present a unique case of Harlequin syndrome without Horner syndrome after contralateral Th3 intradural tumor resection. Harlequin sign in our case presented probably to resection of sympathetic nerves while removing meningioma. Syndrome is rare in neurosurgical procedure, but we think that surgeons must be aware of it.

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Therapeutic effect of OnabotulinumtoxinA in harlequin syndrome and episodic migraine: A case report

Journal of the Neurological Sciences ◽

10.1016/j.jns.2021.118861 ◽

2021 ◽

Vol 429 ◽

pp. 118861

Author(s):

Jose Ricardo Lopez Castellanos ◽

Jose Lopez-Contreras

Keyword(s):

Case Report ◽

Therapeutic Effect ◽

Episodic Migraine ◽

Harlequin Syndrome

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Concomitant Congenital Horner and Harlequin Syndromes: Case Report and Review of Literature

Journal of Pediatric Neurology ◽

10.1055/s-0040-1709461 ◽

2020 ◽

Author(s):

Ayman G. Elnahry ◽

Aisha A. Gamal Eldin ◽

Aya G. Elnahry ◽

Gehad A. Elnahry

Keyword(s):

Case Report ◽

Autonomic Dysfunction ◽

Rare Case ◽

Rare Condition ◽

Male Infant ◽

The Other ◽

Review Of Literature ◽

Harlequin Syndrome ◽

Congenital Condition ◽

Autonomic Disturbances

AbstractHarlequin syndrome is a condition characterized by autonomic dysfunction leading to hemifacial flushing on one side with pallor and impaired sweating on the other side. It is a rare condition that can be both congenital and acquired, with congenital cases being rarer, comprising ∼6% of all Harlequin syndrome cases. Harlequin syndrome is usually associated with other autonomic disturbances including Horner syndrome especially when presenting as a congenital condition. We reported the findings of a rare case of concomitant congenital Horner and Harlequin syndromes in an otherwise healthy 4-month-old male infant patient and provided a review of the current literature.

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Idiopathic harlequin syndrome: a case report and literature review

Pan African Medical Journal ◽

10.11604/pamj.2019.33.141.18102 ◽

2019 ◽

Vol 33 ◽

Author(s):

Khadija Elboukhari ◽

Hanane Baybay ◽

Sara Elloudi ◽

Zakia Douhi ◽

Fatima Zahra Mernissi

Keyword(s):

Case Report ◽

Literature Review ◽

Harlequin Syndrome

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Idiopathic Harlequin Syndrome in a Young Women during Physical Exercise: A Case report and literature review

Integrative Journal of Medical Sciences ◽

10.15342/ijms.2021.317 ◽

2021 ◽

Vol 8 ◽

Author(s):

Amal Hajjij ◽

Madiha El Jazouli ◽

Othmane Haddani ◽

Fouad Benariba

Keyword(s):

Case Report ◽

Young Women ◽

Treatment Options ◽

Sympathetic Nerves ◽

The Other ◽

Harlequin Syndrome ◽

The Face ◽

Surgical Options ◽

Botulinum Toxin Injections ◽

Rule Out

The Harlequin syndrome is a rare and benign disorder of the sympathetic nerves that is mostly idiopathic. It is characterized by an erythema associated with an intense sweating of one side of the face, and a pallor and anhidrosis of the other side. A complete workup to rule out secondary organic causes should be done properly. The medical or surgical options are only required if the patient is in demand of treatment. Psychological and social impacts of this condition should be considered while consulting patients for treatment options. We report a case of a 24 years old female patient who presented this syndrome during exercise and heat stress. She improved considerably after botulinum toxin injections.

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Harlequin syndrome: A case report in Uyo, southern Nigeria

Journal of the Neurological Sciences ◽

10.1016/j.jns.2019.10.1351 ◽

2019 ◽

Vol 405 ◽

pp. 282-283

Author(s):

B. Ekeh ◽

D.O. Okeke ◽

E.M. Nyoyoko

Keyword(s):

Case Report ◽

Harlequin Syndrome ◽

Southern Nigeria

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Idiopathic Harlequin Syndrome Manifesting during Exercise: A Case Report and Review of the Literature

Case Reports in Medicine ◽

10.1155/2017/5342593 ◽

2017 ◽

Vol 2017 ◽

pp. 1-3 ◽

Cited By ~ 4

Author(s):

Hussein Algahtani ◽

Bader Shirah ◽

Raghad Algahtani ◽

Abdulah Alkahtani

Keyword(s):

Case Report ◽

Botulinum Toxin ◽

Psychological Factors ◽

Botulinum Toxin Injection ◽

Medical Conditions ◽

Review Of The Literature ◽

Facial Flushing ◽

Harlequin Syndrome ◽

Surgical Treatments

Harlequin syndrome is a rare autonomic disorder characterized by unilateral facial flushing and sweating with contralateral anhidrosis induced by exercise, heat, and emotion. It is usually idiopathic but could be the first manifestation of several serious underlying medical conditions. Medical or surgical treatments are not required for idiopathic Harlequin syndrome, but social and psychological factors may indicate sympathectomy or botulinum toxin injection. In this article, we report a case of idiopathic Harlequin syndrome and review the literature.

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Harlequin syndrome in childhood: case report

Anais Brasileiros de Dermatologia ◽

10.1590/s0365-05962012000600015 ◽

2012 ◽

Vol 87 (6) ◽

pp. 907-909 ◽

Cited By ~ 6

Author(s):

Juliano de Avelar Breunig ◽

Mariana Hartmann ◽

Cristiano Firpo Freire ◽

Hiram Larangeira de Almeida Jr

Keyword(s):

Case Report ◽

Literature Review ◽

Neurological Examination ◽

Emotional Factors ◽

Harlequin Syndrome ◽

The Face ◽

History Of

Harlequin syndrome happens in only one side of the face. In the affected half, the face does not sweat or flush even with simulation. Arms and trunk could also be affected. This condition is induced by heat, exercise and emotional factors. The article reports a case of a nine-year-old female with a 3-year history of unilateral flushing and sweating after exercise; a brief literature review is included. Despite the rarity of this syndrome, dermatologists should recognize this condition and refer these patients to ophthalmological and neurological examination.

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