Introduction. Alcoholic acute pancreatitis occurs in 10% of alcoholics, who
take more than 80g alcohol daily. Different biochemical markers are used to
diagnose acute pancreatitis, and some of them may help in establishing
etiology of acute pancreatitis. Material and Methods. This study is a
prospective review of 21 patients. All patients were hospitalized at the
Department for Gastroenterology and Hepatology or at the Department for
Surgery of the Clinical Centre of Nis in the period from August 1st 2009 to
March 1st 2010 with diagnosis of acute alcoholic pancreatitis. Detailed
anamnesis, clinical examination, biochemical analyses and ultrasonography of
the upper abdomen were done in all patients. All patients provided data on
alcohol abuse. Results. The analysis of the corresponding biochemical
parameters revealed a statistically significant correlation between the
following values: serum amylase and serum lipase (R=0.964674; p<0.001),
cholesterol and triglycerides (R=0.93789; p<0.001), total and direct
bilirubin (R=0.857899; p<0.001) and between aspartate aminotransferase and
alanine aminotransferase (R=0.824461, p<0.001) in patients with alcoholic
acute pancreatitis. In addition, there was a statistically significant
correlation between the values of serum amylase and urinary amylase
(R=0.582742, p<0.001). Discussion. The analysis of biochemical markers showed
that some of them were significant for beforehand diagnosis of alcoholic
acute pancreatitis, which is in accordance with other studies. Conclusion
Some biochemical parameters can be potential predictors of alcoholic acute
pancreatitis (lipase/amylase ratio >2, greater ratio of aspartate
aminotransferase/ alanine aminotransferase, enhanced triglycerides and values
of mean corpuscular volume.