scholarly journals Recent Landmark Studies on Head and Neck Cancers: Evidence-Based Fundamentals of Modern Therapeutic Approaches

2015 ◽  
Vol 53 (1) ◽  
pp. 26-31
Author(s):  
Utku Aydil
2020 ◽  
Vol 11 (10) ◽  
pp. 637-651 ◽  
Author(s):  
Swatantra Shrivastava ◽  
Ravleen Nagi ◽  
Saurabh Sharma ◽  
Sajid Ahmed Rasul Sanadi ◽  
Elbadri Taha Dafallah ◽  
...  

Cancer is a major public health burden worldwide, affecting millions of people each year. One of the major hallmarks of cancer is rapid growth and progression by evasion of host immune responses. Tumor resistance to conventional anticancer drugs by several mechanisms, such as drug inactivation, efflux pumps and enhanced toxicity to normal cells decreases their clinical efficacy. These limitations resulted in the development of new targeted agents, such as monoclonal antibodies and small molecule inhibitors that have high tumor specificity. This paper discusses the therapeutic applications of novel molecular targeted agents and immunotherapy as an alternative treatment option for head and neck cancers, as well as provides insight into future therapeutic approaches for advanced head and neck cancers.


2006 ◽  
Vol 12 (2) ◽  
pp. 44 ◽  
Author(s):  
JaiPrakash Agarwal ◽  
SarbaniGhosh Laskar ◽  
ShyamKishore Shrivastava ◽  
KetayunArdeshir Dinshaw ◽  
Kaustav Talapatra ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Danhui Wang ◽  
Zhi Li ◽  
Yongjun Wu

With rapid development of science technique and molecular research, a large number of circular RNAs (circRNAs) were discovered. CircRNAs that are a heterogeneous endogenous group of non-coding RNA not only are abundantly and diffusely expressed in mammals but also participate in many biological processes, such as in tumor ingenuity and progress. CircRNAs have rarely open reports in the head and neck cancers (HNC), which are an aggressive malignant tumor with unsatisfactory overall survival rates. The diagnostics and treatments continue to improve while the survival rate of HNC patients has no more obvious improvement. Recent studies that are aimed at exploring the molecular mechanisms of occurrence and progression of circRNAs in HNC provide a valuable insight into potential novel diagnostic and therapeutic approaches. In this review, we summarize the increasing number of published researches on the research progression of circRNAs in HNC, as well as their possible clinical implications on HNC.


2017 ◽  
Vol 16 (4) ◽  
pp. 56-61
Author(s):  
N.S. Grachev ◽  
◽  
I.N. Vorozhtsov ◽  
N.V. Babaskina ◽  
E.Yu. Iaremenko ◽  
...  

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